A5005680258- Coccidia and coccidiosis research
- Veterinary Oncology Research
- Animal Nutrition and Physiology
- IL-33, ST2, and ILC Pathways
- Veterinary medicine and infectious diseases
- Antimicrobial Peptides and Activities
- Helminth infection and control
- Parasitic Infections and Diagnostics
- Microbial infections and disease research
- Parasitic infections in humans and animals
- Gut microbiota and health
- Asthma and respiratory diseases
- Animal Disease Management and Epidemiology
- Respiratory viral infections research
- Polyamine Metabolism and Applications
- Bacterial biofilms and quorum sensing
- Immune Response and Inflammation
- Tracheal and airway disorders
- Vector-Borne Animal Diseases
- Berberine and alkaloids research
- Human-Animal Interaction Studies
- Viral Infections and Vectors
- Virology and Viral Diseases
- Viral Infections and Immunology Research
- Mycobacterium research and diagnosis
Gyeongsang National University
2017-2024
Abstract Background Coccidiosis is a poultry disease that occurs worldwide and caused by Eimeria species. The infection associated with reduced feed efficiency, body weight gain, egg production. This study aimed to investigate the current status of coccidiosis anticoccidial resistance drugs used as part control strategies for this in Korean chicken farms. Results An overall prevalence 75% (291/388) was found. Positive farms contained several species (mean = 4.2). Of positive samples, E....
Avian coccidiosis has a major economic impact on the poultry industry, it is caused by 7 species of Eimeria, and been primarily controlled using chemotherapeutic agents. Due to emergence drug-resistant strains, alternative control strategies are needed. We assessed anticoccidial effects berberine-based diets in broiler chickens following oral infection with 5 Eimeria (E. acervulina, E. maxima, tenella, mitis, praecox). When 0.2% berberine, concentration that does not affect weight gain, was...
Riemerella anatipestifer (RA) is an economically important pathogen in the duck industry worldwide that causes high mortality and morbidity infected birds. We previously found upregulated IL-17A expression ducks with RA participates pathogenesis of disease, but this mechanism not linked to IL-23, which primarily promotes Th17 cell differentiation proliferation. RNA sequencing analysis was used study investigate other mechanisms upregulation infection. A possible interaction IL-26 IL-17...
Avian coccidiosis is a disease caused by members of the genus Eimeria. Huge economic losses incurred global poultry industry due to have increased need for cost-effective and easily available recombinant vaccines. Microneme protein 2 (MIC2) surface antigen 1 (SAG1) E. tenella been recognised as potential vaccine candidates. However, genetic diversity antigens in field isolates, which affects efficacy, has yet be largely investigated. Here, we analysed natural selection etmic2 etsag1 Korean...
R. anatipestifer (RA) is one of the most harmful bacterial pathogens affecting duck industry, and infection associated with production proinflammatory cytokines, including IL-17A. Another cytokine, IL-23, critical for development Th17 cells, which produce IL-17. However, IL-23 roles have not been studied in this infection. Here, we describe identification mRNA expression analysis IL-23p19 (duIL-23p19) splenic lymphocytes macrophages stimulated killed RA spleens RA-infected ducks. Expression...
Riemerella anatipestifer is one of the most devastating pathogens affecting global duck farms. Infection involved in secretion proinflammatory cytokines, including interleukin- (IL-) 17A. During immune response to infection, IL-22 and IL-17A are often produced concurrently at high levels inflamed tissues. Little known about (duIL-22) during R. infection. We describe characterization duIL-22 its mRNA expression analysis splenic lymphocytes macrophages treated with heat-killed spleens livers...
Coccidiosis in chickens is an intestinal parasitic disease caused by protozoan parasites named Eimeria spp. In some infections, lymphocytes are known to highly express chicken NK-lysin (cNK-lysin), antimicrobial peptide with anticoccidial activity. Therefore, this study aims investigate the expression of cNK-lysin E. necatrix-infected and its role necatrix infection. The transcript was significantly increased sporozoites-treated lymphocytes. infection, induced but not spleen. recombinant...
Avian influenza virus (AIV) is a pathogen with zoonotic and pandemic potential. Migratory birds are natural reservoirs of all known subtypes AIVs, except for H17N10 H18N11, they have been implicated in previous highly pathogenic avian outbreaks worldwide. This study identified characterized the first isolate H13N6 subtype from Vega gull (Larus vegae mongolicus) South Korea. The amino acid sequence hemagglutinin gene showed low AIV various substitutions were found compared to reference H13...
The spread of antibiotic-resistant Enterococcus in the poultry industry poses significant public health challenges due to multidrug resistance and biofilm formation. We investigated antibiotic profiles characteristics E. faecalis faecium isolates from chicken meat slaughterhouses South Korea. Ninety-six (forty-eight each faecium) were collected between March September 2022. Both species analyzed using MALDI-TOF, PCR, susceptibility testing, assays. A high level was observed (95.8%) (93.8%),...
Live coccidiosis vaccines have mainly been used to reduce Eimeria species infection, which is considered the most economically important disease in poultry industry. Evaluation data on vaccine effectiveness through large-scale field experiments are lacking, especially broilers. Thus, of a commercial was evaluated approximately 900,000 chicks reared three open-broiler farms where prevalent. The vaccine’s after vaccination 1-day-old monitored using parameters (lesion score, fecal oocyst...
Nipah virus (NiV), of the Paramyxoviridae family, causes highly fatal infections in humans and is associated with severe neurological respiratory diseases. Currently, no commercial vaccine available for human use. Here, eight structure-based mammalian-expressed recombinant proteins harboring NiV surface proteins, fusion glycoprotein (F), major attachment (G) were produced. Specifically, prefusion NiV-F and/or NiV-G glycoproteins expressed monomeric, multimeric (trimeric F tetra G), or...
Riemerella (R . ) anatipestifer poses a significant threat to ducks, resulting in mortality rates ranging from 5–75%. This disease is highly infectious and economically consequential for domestic ducks. Although other avian species, such as chickens, also display susceptibility, the impact comparatively less severe than IL-17A has pronounced correlation with R infection which chickens. study performed an vitro transcriptome analysis using chicken splenic lymphocytes collected at 4-, 8-,...
Three parameters, body weight gain (BWG), intestinal lesion score (LS) and fecal oocyst shedding, were compared in broilers infected with major parasitic species; Eimeria acervulina, E. maxima, tenella. First, two- three-week-old chickens infection showed LS of approximately 3, but two-week-old more correlated BWG. Second, significant differences BWG observed between male female challenged Eimeria. Finally, maxima-infected among three species a higher relationship LS, suggesting...
3,3’-Diindolylmethane (DIM) is found in cruciferous vegetables and used to treat various inflammatory diseases because of its potential anti-inflammatory effects. To investigate effects DIM Riemerella anatipestifer- infected ducks which induce upregulation cytokines, were treated orally with at dose 200 mg/kg/day the following day R . anatipestifer Infected DIM-treated exhibited 14% increased survival rate significantly decreased bacterial burden compared untreated ducks. Next, effect on...
Abstract Background: Avian coccidiosis is a major disease within the poultry industry caused by species of Eimeria, an intestinal protozoan parasite. Body weight gain, lesion score, and fecal oocyst shedding are parameters that have been used to assess protective effects various treatments in Eimeria -infected chickens. The objective this study was compare aforementioned broiler chickens infected with parasitic such as E. acervulina , maxima tenella . Results: results body showed similar...