Abstract Typhoon Haiyan, which struck the Philippines in November 2013, was an extremely intense tropical cyclone that had a catastrophic impact. The minimum central pressure of Haiyan 895 hPa, making it strongest typhoon to make landfall on major island western North Pacific Ocean. characteristics and its related storm surge are estimated by numerical experiments using weather prediction models model. Based analysis best hindcast results, level 5–6 m local amplification water surface...

The N-linked oligosaccharide structures on the envelope glycoprotein gp120 of human immunodeficiency virus 1 derived from chronically infected lymphoblastoid (H9) cells have been investigated by enzymatic microsequencing after release protein hydrazinolysis, labeling with NaB3H4, and chromatography adsorbent columns Phaseolus vulgaris erythrophytohemagglutinin Ricinus communis agglutinin (Mr 120,000) Bio-Gel P-4. A substantially greater diversity was detected than among those released...

Abstract Increases of tropical cyclone intensity with global warming have been demonstrated by historical data studies and theory. This raises great concern regarding future changes in typhoon intensity. The present study addressed the problem to what extent supertyphoons will become intense climate late 21st century. Very high resolution downscale experiments using a cloud‐resolving model without convective parameterizations were performed for 30 most typhoons obtained from 20 km mesh...

Abstract Precipitation in excess of 100 mm h−1 Hiroshima, Japan, on 19 August 2014, caused a flash flood that resulted 75 deaths and destroyed 330 houses. This study examined the meteorological background this fatal flood. During event, considerable filamentary transport water vapor from Indochina Peninsula to Japanese islands occurred, forming so-called atmospheric river (AR). AR had deep structure with an amount free tropospheric moisture comparable boundary layer. Furthermore, cutoff low...

Abstract This study focused on an explosive cyclone migrating along the southern periphery of Kuroshio/Kuroshio Extension in middle January 2013 and examined how those warm currents played active role rapid development using a high-resolution coupled atmosphere–ocean regional model. The evolutions surface fronts simulated resemble Shapiro–Keyser At time maximum deepening rate, strong mesoscale diabatic heating areas appear over bent-back front east center. Diabatic eastern is mainly induced...

Flavanone 3-hydroxylase (F3H), a key enzyme in the flavonoid biosynthetic pathway, plays an important role regulation of flavonols and anthocyanidins accumulation. Citrus fruit is rich source flavonoids with varied compositions among different varieties. To date, study on F3H limited citrus, its roles regulating accumulation citrus are still unclear.In this study, we isolated CitF3H from three varieties, Satsuma mandarin (Citrus unshiu Marc.), Ponkan (C. reticulata Blanco) blood orange...

The nuclear magnetic specific heat of bcc solid $^{3}\mathrm{He}$ molar volume 24.15 ${\mathrm{cm}}^{3}$/mole has been measured as a function temperature $T$ and field $B$ for $0.6 \mathrm{mK} <T<40 \mathrm{mK}$ $B<8.0$ T. discontinuous change in entropy following the high-field to low-field phase transition also measured. diagram determined. observed specific-heat peak at ordering ${T}_{N}$ is discussed connection with nature transition.

FBXW 7 is a ubiquitin ligase that mediates ubiquitylation of oncoproteins, such as c‐Myc, cyclin E, Notch and c‐Jun. known tumor‐suppressor gene, mutations in have been reported various human malignancies. In this study, we examined the sequences p53 genes 57 ovarian cancer clinical samples. Interestingly, found no associated with amino acid changes. We also investigated expression levels 126 epithelial tumors. was negatively correlated malignant potential That to say, samples were...

Abstract The dynamical response of rapidly developing extratropical cyclones to sea surface temperature (SST) variations over the western Kuroshio–Oyashio confluence (WKOC) region was examined by using regional cloud‐resolving simulations. This study specifically highlights an explosive cyclone that occurred in early February 2014 and includes a real SST experiment (CNTL run) two sensitivity experiments with warm cool anomalies WKOC (warm runs). results derived from CNTL run indicated...

Aquatic Coleoptera and Hemiptera insects primarily inhabit lentic waters, many of which are at risk extinction due to development, agriculture, invasive alien species. Environmental DNA (eDNA) analysis has recently emerged as a powerful tool for conducting comprehensive distribution surveys. The cytochrome c oxidase subunit I (COI) universal primers conventionally used barcoding by non-specific amplification frequent failures. Primers in the mitochondrial 16S region that alleviate these...

Three hyperthermophilic sulfur-dependent heterotrophs were isolated from a shallow submarine hydrothermal system at an inlet of Kodakara-jima island, Kagoshima, Japan. The isolates grew 60 to 97 degrees C, with the optimum temperatures 85 90 C. Sensitivity rifampin and existence ether lipids indicated that are archaea. Partial sequencing genes coding for 16S rRNA showed three closely related genus Thermococcus. They on proteinaceous mixtures, such as yeast extract, Casamino Acids, purified...

Carotenoid derived volatiles are important fragrance compounds, which contribute to the scents of flowers from diverse taxa. A famous example is represented by Osmanthus fragrans where apocarotenoids account for more than 20% all volatiles. In recent years, bio-degradation carotenoids has been shown be an route formation. Here, we report on contribution O. carotenoid cleavage dioxygenase 1 synthesis two predominant C(13)-apocarotenoids, α- and β-ionone, α-and β-carotene, respectively.

Abstract Intense tropical cyclones (TCs) sometimes cause huge disasters, so it is imperative to explore the impacts of climate change on such TCs. Therefore, authors conducted numerical simulations most destructive historical TC in Japanese history, Typhoon Vera (1959), current and a global warming climate. The used four nonhydrostatic models with horizontal resolution 5 km: cloud-resolving storm simulator, fifth-generation Pennsylvania State University–National Center for Atmospheric...

d4PDFから得た降水量データを用い,極値降水量の確率分布の将来変化を分析するとともに,降雨流出モデルを介して推定した極値流量の確率分布の将来変化を分析した.また,再現期間1000年相当の流量規模を調べ,それらをもたらす降水要因を考察した.対象流域は荒川流域,庄内川流域,淀川流域である.以下の結果を得た.1) 観測値とd4PDF過去実験から得られる年最大24時間降水量の頻度分布は非超過確率0.95以下ではよく対応した.2) 4度上昇実験の200年確率年最大24時間降水量は,過去実験のそれの1.3~1.4倍,年最大時間流量では1.5~1.7倍となった.3) 4度上昇実験の200年確率年最大降水量と過去実験の900年確率年最大降水量とがほぼ同じ値となった.4) 既往大洪水をもたらした降水要因とd4PDFで再現・予測される大洪水の降水要因はよく適合した.

Abstract Using a cloud‐resolving regional model and Lagrangian diagnostics, we assess positive feedback process between tropical cyclone (TC) intensity the moisture conveyor belt (MCB), which connects TC Indian Ocean (IO), South China Sea (SCS), Philippine (PS) vapors, from macroscopic view. We performed sensitivity experiments that modified observed sea surface temperature field over IO SCS to regulate MCB behavior, examined remote response of prototypical TC. The results show connection...

The prognosis of patients with high-grade or advanced-stage endometrial cancer remains poor. As stem-like cells (CSCs) are thought to be associated cancers, it is essential investigate the molecular mechanisms that regulate CSCs. Dual-specificity phosphatase 6 (DUSP6) functions as a negative-feedback regulator MAPK-ERK1/2 signaling, but its role in unknown. We investigated whether DUSP6 involved cell stemness using lines and specimens from patients. induced expression CSC-related genes...

We report here the complete nucleotide sequence of pEntH10407 (65 147 bp), an enterotoxigenic Escherichia coli enterotoxin plasmid (Ent plasmid), which is self-transmissible at low frequency. Within plasmid, we identified 100 open reading frames (ORFs) could encode polypeptides. These ORFs included regions encoding heat-labile (LT) and heat-stable (STIa) enterotoxins, tools for replication incomplete tra (conjugation) region. The LT STIa region was located 13.5 kb apart surrounded by three...

Abstract Although Y14 is known to be a component of the exon junction complex, we previously reported that regulates IL-6–induced STAT3 activation. In this study, showed endogenous positively regulated TNF-α–induced IL-6 expression in HeLa cells. Small interfering RNA–mediated Y14-knockdown reduced and NF-κB–mediated transcriptional activity, phosphorylation/degradation IκBα, nuclear localization NF-κB/p65. As case stimuli, enhanced phosphorylation, which important for its retention....

Abstract The structure of mesoscale precipitation within monsoon depressions is still not as well‐known the synoptic‐scale composite cloud and structure. Here, using observational data from multi‐satellite sensors a cloud‐resolving regional model, we investigate three‐dimensional systems in different stages life cycle depression. Effects latent heating Bay Bengal (BoB) on development depression are also evaluated sensitivity experiments with model. A typical developed 17 August 2016 over...

Inelastic neutron measurements have been performed on a quasi-one-dimensional spin-gap system CuNb 2 O 6 . From the dispersion curve of triplet excitation, compound has found to ferromagnetic-antiferromagnetic alternating bond chain. The temperature ( T ) dependence magnetic excitation spectra indicates that both singlet correlation and antiferromagnetic begin grow with decreasing at around 0 , where spin susceptibility becomes maximum.

Electron-impact ionization-rate coefficients are obtained for lithiumlike, heliumlike, and hydrogenlike ions by the plasma spectroscopy method. The is produced in a 140-kJ large-bore theta pinch, electron density temperature determined 90\ifmmode^\circ\else\textdegree\fi{} Thomson scattering. basic requirements of evaluation technique employed briefly discussed results compared with other measurements theoretical calculations.

Temperature‐dependent compositional changes of phospholipids and their fatty acids were analysed in Yersinia enterocolitica grown at 5°, 25° 37°C. The relative amounts the four phospholipids, phosphatidylethanolamine (75–78%), phosphatidylglycerol (10–11%), cardiolipin (<7%) lysophosphatidylethanolamine (<5%), essentially same all growth temperatures. degree acid unsaturation increased with decrease temperature, mainly due to an increase C16:1 C18:1 a corresponding C16;0, C18:0 cyclo C17:0....

A granulation experiment was conducted using different granulator and formulation. The purpose of the to clarify end-point gain high yields spherical, well-compacted granules fine granules, investigate agitation-granulating process. fluctuation electric-power consumption continuously measured during operation, it determined that measurement power helpful for determining process end point.One results divided into four phases, at initial stage phase IV are possibly produced (granulation...