Andrew D. McRae

ORCID: 0000-0003-2743-4290
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About
Contact & Profiles
Research Areas
  • Acute Myocardial Infarction Research
  • Emergency and Acute Care Studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Ethics in Clinical Research
  • Cardiac Imaging and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Arrhythmias and Treatments
  • COVID-19 and healthcare impacts
  • Meta-analysis and systematic reviews
  • Health Systems, Economic Evaluations, Quality of Life
  • COVID-19 Clinical Research Studies
  • Healthcare cost, quality, practices
  • Healthcare Policy and Management
  • Trauma and Emergency Care Studies
  • Medical Coding and Health Information
  • Radiology practices and education
  • Kidney Stones and Urolithiasis Treatments
  • Ultrasound in Clinical Applications
  • Heart Failure Treatment and Management
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Heart Rate Variability and Autonomic Control
  • Pediatric Urology and Nephrology Studies
  • Ethics in medical practice

University of Calgary
2016-2025

Libin Cardiovascular Institute of Alberta
2021-2025

Alberta Health Services
2015-2025

University of Alberta
2018-2025

Queen's University
2004-2025

Foothills Medical Centre
2013-2024

Rockyview General Hospital
2016-2023

University of Ottawa
2016-2023

University of British Columbia
2020-2022

Vancouver Coastal Health
2022

The Ottawa Ethics of Cluster Trials Consensus Group sets out 15 recommendations for the ethical design and conduct cluster randomized trials.

10.1371/journal.pmed.1001346 article EN cc-by PLoS Medicine 2012-11-20

The cluster randomized trial (CRT) is used increasingly in knowledge translation research, quality improvement community based intervention studies, public health and research developing countries. However, trials raise difficult ethical issues that challenge researchers, ethics committees, regulators, sponsors as they seek to fulfill responsibly their respective roles. Our project will provide a systematic analysis of the trials. Here we have outlined series six areas inquiry must be...

10.1186/1745-6215-12-100 article EN cc-by Trials 2011-04-20

The management of patients with syncope in the emergency department (ED) is challenging because no robust risk tool available has been recommended for clinical use.To validate Canadian Syncope Risk Score (CSRS) a new cohort to determine its ability predict 30-day serious outcomes not evident during index ED evaluation.This prospective multicenter study conducted at 9 EDs across Canada included 16 years and older who presented within 24 hours syncope. Patients were enrolled from March 2014...

10.1001/jamainternmed.2020.0288 article EN JAMA Internal Medicine 2020-03-23

This article is part of a series papers examining ethical issues in cluster randomized trials (CRTs) health research. In the introductory paper this series, we set out six areas inquiry that must be addressed if trial to on firm foundation. addresses second questions posed, namely, from whom, when, and how informed consent obtained CRTs research? The principle respect for persons implies researchers are generally obligated obtain research subjects. Aspects CRT design, including...

10.1186/1745-6215-12-202 article EN cc-by Trials 2011-09-09

Administrative data is a useful tool for research and quality improvement; however, validity of findings based on these depends their reliability. Diagnoses assigned by physicians are subsequently converted nosologists to ICD-10 codes (International Statistical Classification Diseases Related Health Problems, 10th Revision). Several groups have reported ICD-9 coding errors in inpatient that implications research, improvement, policymaking, but few assessed code ambulatory care databases. Our...

10.1186/s12874-017-0361-1 article EN cc-by BMC Medical Research Methodology 2017-06-08

Cluster randomized trials (CRTs) pose ethical challenges for investigators and ethics committees. This study describes the views experiences of CRT researchers with respect to: (1) in CRTs; (2) review process (3) need comprehensive guidelines CRTs. Descriptive qualitative analysis interviews conducted a purposive sample 20 experienced researchers. Informants expressed concern over potential bias that may result from requirements to obtain informed consent research participants suggested...

10.1186/1745-6215-14-1 article EN cc-by Trials 2013-01-01

Advances in ultrasound imaging technology have made it more accessible to prehospital providers. Little is known about how being used the environment and we suspect that not widely North America at this time. We believe EMS system characteristics such as provider training, size, population served, type of transport will be associated with use or non-use ultrasound. Our study objective was describe current America. This a cross-sectional survey distributed directors on National Association...

10.1186/1471-227x-14-6 article EN cc-by BMC Emergency Medicine 2014-03-01

The optimal duration of cardiac rhythm monitoring after emergency department (ED) presentation for syncope is poorly described. We sought to describe the incidence and time arrhythmia occurrence inform decisions regarding based on ED risk stratification.We conducted a prospective cohort study with enrolled adult patients (≥16 years old) presenting within 24 hours at 6 EDs. collected baseline characteristics, arrival, Canadian Syncope Risk Score (CSRS) category. followed subjects 30 days, our...

10.1161/circulationaha.118.036088 article EN Circulation 2019-01-21

<h3>Background:</h3> Emergency physicians lack high-quality evidence for many diagnostic and treatment decisions made patients with suspected or confirmed coronavirus disease 2019 (COVID-19). Our objective is to describe the methods used collect ensure data quality of a multicentre registry presenting emergency department COVID-19. <h3>Methods:</h3> This methodology study describes population-based that has been enrolling consecutive COVID-19 since Mar. 1, 2020. Most are collected from...

10.9778/cmajo.20200290 article EN CMAJ Open 2021-01-01

This article is part of a series papers examining ethical issues in cluster randomized trials (CRTs) health research. In the introductory paper this series, we set out six areas inquiry that must be addressed if CRT to on firm foundation. addresses first questions posed, namely, who research subject research? The identification human subjects logically prior application protections as ethics and regulation. Aspects design, including fact single study units randomization, experimentation,...

10.1186/1745-6215-12-183 article EN cc-by Trials 2011-07-26

Despite several expert panel recommendations and cellulitis treatment guidelines, there are currently no clinical decision rules to assist clinicians in deciding which emergency department (ED) patients should be treated with oral antibiotics require intravenous (IV) therapy at first presentation of amenable outpatient treatment. The objective was determine risk factors associated adult presenting the ED who fail initial antibiotic as outpatients a change or admission hospital. This...

10.1111/acem.12371 article EN Academic Emergency Medicine 2014-05-01

Abstract Objectives We previously developed the Ottawa Heart Failure Risk Scale ( OHFRS ) to assist with disposition decisions for acute heart failure patients in emergency department ED ). sought prospectively evaluate accuracy, acceptability, and potential impact of . Methods This prospective observational cohort study was conducted at six tertiary hospital s. Patients were evaluated by physicians 10 criteria then followed 30 days. Quantitative NT ‐pro BNP measured where feasible. Serious...

10.1111/acem.13141 article EN Academic Emergency Medicine 2016-12-15

Mild traumatic brain injury (mTBI) is a common problem. Depending on diagnostic criteria, 13 to 62% of those patients develop persistent post-concussion symptoms (PPCS). The main objective this prospective multi-center study derive and validate clinical decision rule (CDR) for the early prediction PPCS. Patients aged ≥14 years were included if they presented one our seven participating emergency departments (EDs) within 24 h an mTBI. Clinical data collected in ED, symptom evolution was...

10.1089/neu.2022.0026 article EN cc-by-nc Journal of Neurotrauma 2022-06-29

Abstract Many health authorities differentiate hospitalizations in patients infected with SARS-CoV-2 as being “for COVID-19” (due to direct manifestations of infection) versus an “incidental” finding someone admitted for unrelated condition. We conducted a retrospective cohort study all hospitalized via 47 Canadian emergency departments, March 2020-July 2022 determine whether infection are less burden and the healthcare system. Using priori standardized definitions applied hospital discharge...

10.1038/s41598-023-33569-2 article EN cc-by Scientific Reports 2023-04-24

<h3>Background:</h3> The relation between emergency department opioid prescribing and subsequent harm is complex poorly studied. We sought to quantify adverse outcomes, incremental risk, rates of prolonged use among patients receiving an prescription propensity-matched controls. <h3>Methods:</h3> used administrative data sample all Alberta visits over 10 years, excluding with cancer, palliative care, or concurrent use. Treated filled within 72 hours after their index visit; untreated did...

10.1503/cmaj.241542 article EN cc-by-nc-nd Canadian Medical Association Journal 2025-02-09
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