A5021367829- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Memory Processes and Influences
- Child and Animal Learning Development
- Neurotransmitter Receptor Influence on Behavior
- Neural dynamics and brain function
- Sleep and Wakefulness Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cognitive Science and Mapping
- Zebrafish Biomedical Research Applications
- Medicinal Plants and Neuroprotection
- Cannabis and Cannabinoid Research
- Medical Malpractice and Liability Issues
- Circadian rhythm and melatonin
- Early Childhood Education and Development
- Cholinesterase and Neurodegenerative Diseases
- Nicotinic Acetylcholine Receptors Study
- Mental Health Research Topics
- Cognitive Abilities and Testing
- Tryptophan and brain disorders
- Anesthesia and Neurotoxicity Research
- Cognitive Functions and Memory
- Sleep and related disorders
Universidade Federal da Paraíba
2014-2025
Universidade Federal do Rio Grande do Norte
2008-2012
Episodic memory reflects the capacity to recollect what, where and when a specific event happened in an integrative manner. Animal studies have suggested that medial temporal lobe pre-frontal cortex are important for episodic-like formation. The goal of present study was evaluate whether there different patterns expression immediate early genes c-Fos Zif-268 these cortical areas after rats exposed object recognition tasks with cognitive demands. Male were randomly assigned five groups: home...
ABSTRACT The ability to form different neural representations for similar inputs is a central process of episodic memory. Although the dorsal dentate gyrus and CA3 have been indicated as important in this phenomenon, neuronal circuits underlying spatiotemporal memory processing with levels spatial similarity are still elusive. In study, we measured expression immediate early gene c‐Fos evaluate brain areas activated when rats recalled temporal order object locations task, either high or low...
Episodic memory depends on the recollection of spatial and temporal aspects past experiences in which hippocampus plays a critical role. Studies hippocampal lesions rodents have shown that dentate gyrus (DG) CA3 are necessary to detect object displacement tasks. However, understanding real-time oscillatory activity underlying discrimination subtle pronounced displacements remains elusive. Here, we chronically implanted microelectrode arrays adult male Wistar rats record network oscillations...
Epilepsy is a chronic neurological disorder affecting 1-2% of world population, and one-third patients are refractory to pharmacological treatment. This fact has stimulated research for new antiepileptic drugs natural products have been an important source. trans-Anethole (TAN) phenylpropanoid, component some essential oils, extracted from plants, its effects little studied. Therefore, this study aimed at investigating the TAN effect in classic seizure models evaluate electroencephalographic...
Episodic memory was initially believed to be unique humans. However, studies demonstrate that nonhuman species discriminate items based on the triad what, where and when. Here we addressed role of dorsal hippocampal subfield CA1 in an integrative what-where-when task Wistar rats. We performed bilateral inactivation with GABAA agonist muscimol previously task. As expected, sham-operated animals recollected for objects (what), their places (where) temporal order (when). impaired performance...
Endocannabinoids (eCBs) modulate a variety of brain functions via activation the widely expressed CB1 receptor. One site high density this receptor is basolateral amygdala (BLA), structure involved in formation aversive memories. The and blockade receptors by systemic or hippocampal drug administrations have been shown to modify memory processing. However, little known about role BLA endocannabinoid system Additionally, transmission seems be related emotional states, but relevance these...
Studies have shown a time-of-day of training effect on long-term explicit memory with greater being in the afternoon than morning. However, these studies did not control chronotype variable. Therefore, purpose this study was to assess if would continue variable were controlled, addition identifying occurrence possible synchronic effect. A total 68 undergraduates classified as morning, intermediate, or types. The subjects listened list 10 words during phase and immediately performed...
Major depression is a disorder with high prevalence in women and associated biological, affective, cognitive changes.In the present study we evaluated pattern of recognition emotional attribution major depressive healthy volunteers.Facial expressions four basic emotions (happiness, fear, sadness, anger) that were presented at intensities (25, 50, 75, 100%) neutral faces used as stimuli.Compared volunteers, who diagnosed showed negative bias processing.The clinical group greater sadness...
Episodic memory (EM) is a subsystem responsible for storing and evoking information about the "What", "Where" "When" elements of an event in integrated way. This capacity depends structures with hippocampus prefrontal cortex. The effect aging on some capacities mediated by these areas, such as influence number objects coding EM, remains unexplored. present study examined recall young older adults EM task which used 2, 4 6 items associated specific space-temporal contexts. showed better...
A number of studies have provided evidence that animals, including rats, remember past episodes. However, few experiments addressed episodic-like memory from a social perspective. In the present study, we evaluated Wistar rats in WWWhen/ELM task as single setups and dyads, applying long retention interval. We also investigated behaviors could subserve emergence this type memory. found only tested setting were able to recollect an integrated lasted 24 h. Additionally, dyads presented higher...
Models of episodic memory are successfully established using spontaneous object recognition tasks in rodents. In this review, we present behavioral techniques devised to investigate type memory, emphasizing methods based on associations places and temporal order items explored by rats mice. We also provide a review the areas circuitry medial lobe underlying episodic-like considering that large number neurobiology data derived from these protocols. Although commonplace field, there is need...