Lingfeng He

ORCID: 0000-0003-2763-1462
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About
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Research Areas
  • Nuclear Materials and Properties
  • Fusion materials and technologies
  • Advanced ceramic materials synthesis
  • MXene and MAX Phase Materials
  • Nuclear materials and radiation effects
  • Nuclear reactor physics and engineering
  • Advanced materials and composites
  • Radioactive element chemistry and processing
  • High Temperature Alloys and Creep
  • Aluminum Alloys Composites Properties
  • Boron and Carbon Nanomaterials Research
  • Advanced Materials Characterization Techniques
  • Additive Manufacturing Materials and Processes
  • Hydrogen embrittlement and corrosion behaviors in metals
  • Intermetallics and Advanced Alloy Properties
  • High-Temperature Coating Behaviors
  • Metallurgical Processes and Thermodynamics
  • Corrosion Behavior and Inhibition
  • Ion-surface interactions and analysis
  • Electronic and Structural Properties of Oxides
  • High Entropy Alloys Studies
  • Machine Learning in Materials Science
  • Metal and Thin Film Mechanics
  • Molten salt chemistry and electrochemical processes
  • Diamond and Carbon-based Materials Research

Zhejiang International Studies University
2025

Beihang University
2018-2025

Ningbo No.6 Hospital
2025

Nanjing Normal University
2025

Second Affiliated Hospital of Nanchang University
2025

Nanchang University
2025

Idaho National Laboratory
2015-2024

Nagaoka University of Technology
2010-2024

North Carolina State University
2022-2024

Nagaoka University
2011-2024

Allogeneic chimeric antigen receptor T (CAR-T) therapy, also known as universal CAR-T (UCAR-T) offers broad applicability, high production efficiency, and reduced costs, enabling quicker access for patients. However, clinical application remains limited by challenges such immune rejection, issues with potency durability. We first screened a safe effective anti-CD70 scFv to construct cells. Anti-CD70 UCAR-T cells were then generated knocking out TRAC, B2M, HLA-DRA. To address the limitations...

10.3389/fimmu.2024.1531294 article EN cc-by Frontiers in Immunology 2025-01-17

In this work, a bulk Nb 4 AlC 3 ceramic was prepared by an in situ reaction/hot pressing method using Nb, Al, and C as the starting materials. The reaction path, microstructure, physical, mechanical properties of were systematically investigated. thermal expansion coefficient determined 7.2 × 10 −6 K −1 temperature range 200°–1100°C. conductivity increased from 13.5 W·(m·K) at room to 21.2 1227°C, electrical decreased 3.35 6 1.13 Ω ·m 5–300 K. possessed low hardness 2.6 GPa, high flexural...

10.1111/j.1551-2916.2008.02424.x article EN Journal of the American Ceramic Society 2008-04-29

The thermal conductivity of nanocrystalline ceria films grown by unbalanced magnetron sputtering is determined as a function temperature using laser‐based modulated thermoreflectance. exhibit significantly reduced compared with stoichiometric bulk CeO 2 . A variety microstructure imaging techniques including X‐ray diffraction, scanning and transmission electron microscopy, photoelectron analysis, energy loss spectroscopy indicate that the influenced grain boundaries, dislocations, oxygen...

10.1111/jace.12673 article EN Journal of the American Ceramic Society 2013-12-05

Abstract Experimental work aimed at understanding the role of dislocation loops in limiting phonon mediated thermal transport ceramics is presented. Faulted loops, having diameters a few nanometers, were introduced by irradiating polycrystalline cerium dioxide sample with 1.6 MeV protons 700°C. XRD analysis indicated that irradiated samples retained their crystalline structure and exhibit very little lattice expansion suggesting low concentration point defects. Further microstructure...

10.1111/jace.16616 article EN Journal of the American Ceramic Society 2019-05-30

We experimentally realize a universal set of single-bit and two-bit geometric quantum gates by adiabatically controlling solid-state spins in diamond defect. Compared with the nonadiabatic approach, adiabatic scheme for computation offers unique advantage inherent robustness to parameter variations, which is explicitly demonstrated our experiment showing that remain unchanged when driving field amplitude varies factor 2 or detuning fluctuates range comparable inverse gate time. The reported...

10.1103/physrevlett.122.010503 article EN publisher-specific-oa Physical Review Letters 2019-01-09

A dense V 2 AlC ceramic was synthesized by an in situ reaction/hot pressing method using V, Al, and C powders as starting materials. The reaction path investigated. It found that produced a between Al 8 5 C. Single ‐phase could be prepared the optimized molar ratio of V:Al:C=2:1.2:0.9. grain sizes as‐prepared samples were temperature dependent. On increasing from 1400° to 1700°C, mean size increased 49 μm length 19 width 405 106 width. sample sintered at 1500°C exhibited highest flexural...

10.1111/j.1551-2916.2008.02774.x article EN Journal of the American Ceramic Society 2008-11-06

Bulk Ta 4 AlC 3 ceramic was prepared by an in situ reaction synthesis/hot‐pressing method using Ta, Al, and C powders as the starting materials. The lattice parameter a new set of X‐ray diffraction data were obtained. physical mechanical properties investigated. is good electrical thermal conductor. flexural strength fracture toughness are 372 MPa 7.7 MPa·m 1/2 , respectively. Typically, plate‐like layered grains contribute to damage tolerance . After indentation up 200 N load, no obvious...

10.1111/j.1551-2916.2007.01804.x article EN Journal of the American Ceramic Society 2007-06-18

Thermal transport is a key performance metric for thorium dioxide in many applications where defect-generating radiation fields are present. An understanding of the effect nanoscale lattice defects on thermal this material currently unavailable due to lack single crystal from which unit processes may be investigated. In work, series high-quality crystals exposed 2 MeV proton irradiation at room temperature and 600 °C create microscale regions with varying densities types point extended...

10.1063/5.0025384 article EN cc-by APL Materials 2020-11-01

Advanced nuclear reactor concepts aim to use fuels that must withstand unprecedented temperature and radiation extremes. In these fuels, thermal energy transport under irradiation is directly related fuel longevity, safety, arguably one of the most important performance metrics. Here we provide a comprehensive, first-principles-informed treatment phonon mediated in defect-bearing actinide oxide with direct comparison experimental measurements. Pristine proton irradiated thorium dioxide was...

10.1016/j.actamat.2021.116934 article EN cc-by Acta Materialia 2021-04-26
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