A5045367394- Hormonal Regulation and Hypertension
- Blood Pressure and Hypertension Studies
- Adrenal and Paraganglionic Tumors
- Adrenal Hormones and Disorders
- Traditional Chinese Medicine Studies
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular Syncope and Autonomic Disorders
- Nutrition, Genetics, and Disease
- Heart Failure Treatment and Management
- Migraine and Headache Studies
- Medicinal Plants and Bioactive Compounds
- Renal and Vascular Pathologies
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Cardiac Imaging and Diagnostics
- Autophagy in Disease and Therapy
- Cardiovascular Function and Risk Factors
- Inflammasome and immune disorders
- Mitochondrial Function and Pathology
- Cardiovascular Health and Disease Prevention
- Circular RNAs in diseases
- Cardiovascular Disease and Adiposity
First Affiliated Hospital of Fujian Medical University
2015-2025
Fujian Medical University
2014-2025
First Affiliated Hospital of Xi'an Jiaotong University
2019
Background. Myocardial ischemia/reperfusion (MI/R) injury is a common pathology in ischemia heart disease. Long noncoding RNAs (lncRNAs) are significant regulators related to many conditions. This study aimed at exploring the molecule mechanism of lncRNA-mediated competing endogenous RNA (ceRNA) network MI/R. Methods. The dataset profiles MI/R and normal tissues (GSE130217 GSE124176) were obtained from GEO database. Integrated bioinformatics performed screen out differentially expressed...
Abstract Obesity and overweight are closely related to cardiovascular mortality. Arterial stiffness is one of the important risks for diseases strongly with However, relationship between obesity arterial still controversial. A cross‐sectional study was performed examine body fat percentage (BFP), an indicator obesity, carotid‐femoral pulse wave velocity (cfPWV) in 2603 subjects (aged 58.62 ± 11.27 years, male 71.07%, hypertension 64.89%). All participants were divided into four groups...
Abstract Renal Artery Sympathetic Denervation (RDN) can lower blood pressure. Different ablation catheters (single electrode, multi‐electrode) have different scopes of (renal artery main stem and branches). Few studies compared the advantages disadvantages procedures in terms antihypertensive efficacy. To compare efficacy safety 3D reconstruction radiofrequency (3DRA) basket multi‐electrode (BMRA) Denervation. Fifty‐three patients with Refractory hypertension (RHT) were divided into BMRA, (...
To explore the long-term efficacy and safety of renal denervation in patients with RHT CKD, a post hoc analysis eGFR subgroups was completed.Fifty-four refractory hypertension chronic kidney disease were treated RDN enrolled study. Patients divided into three groups according to eGFR: 46-90 ml/min group, 15-45 <15 group. The planned follow-up period 48 months assess 24 h ambulatory blood pressure, function, type antihypertensive medication, complications.The ablation sites GFR group 32.57 ±...
Abstract The purpose of this study was to investigate the mechanism EMP1 action in high glucose (HG)‐induced H9c2 cardiac cell pyroptosis and oxidative injury. Rat cardiomyocytes were exposed 33 mM for 24, 48, or 72 h induce cytotoxicity. EMP1‐siRNA, NLRP3 agonist Nigericin, pcNDA‐RAS used treat cells under HG conditions. Cell Counting Kit (CCK)‐8 assay showed that proliferation decreased following induction, which rescued by knockdown. Our results also suggested siRNA transfection...
Objective. To evaluate the safety and efficacy of adrenal venous sampling (AVS) via cubital vein femoral synchronously. Methods. A total 200 patients with primary aldosteronism admitted to First Hospital Fujian Medical University were enrolled randomly divided into a single-path AVS group (SP, N = 108) multipath (MP, 92). We analyzed clinical characteristics, intubation success rate, procedure cost, fluoroscopy time, complications, contrast dosage, number catheters selected during AVS....
To investigate the occurrence of left ventricular reverse remodeling (LVRR) and its predictive factors in patients with idiopathic or secondary dilated cardiomyopathy (DCM).A cross-sectional survey was conducted a consecutive cohort DCM admitted our department between January, 2012 June, 2016. Based on dynamic echocardiographic findings, LVRR defined as an absolute increase ejection fraction (LVEF) by ≥100% value LVEF ≥45% simultaneously decrease end-diastolic diameter (LVEDD) ≥10 mm LVEDD...
Background: To explore the clinical characteristics of segmental morphological classification infrarenal abdominal aorta and renal artery its significance in guiding catheterization for denervation.Methods: A retrospective analysis was performed 748 patients who underwent angiography computed tomography from January 2016 to December 2018.Based on angulations aorta, were divided into type I (angulation > 135° but <165°, n = 213), II ≤ 135°, 23), no distortion ≥ 165°, 512) groups.In addition,...