A5062538429- Air Quality and Health Impacts
- Nanoparticles: synthesis and applications
- Vehicle emissions and performance
- Air Quality Monitoring and Forecasting
- Atmospheric chemistry and aerosols
- Indoor Air Quality and Microbial Exposure
- Advanced Cellulose Research Studies
- Aerogels and thermal insulation
- Graphene and Nanomaterials Applications
- Catalytic Processes in Materials Science
- Microplastics and Plastic Pollution
- Clay minerals and soil interactions
- Biodiesel Production and Applications
- Particle Dynamics in Fluid Flows
- Advanced Combustion Engine Technologies
- Supercapacitor Materials and Fabrication
- Infection Control and Ventilation
- Arsenic contamination and mitigation
- X-ray Spectroscopy and Fluorescence Analysis
- Catalysis and Hydrodesulfurization Studies
- Healthcare and Environmental Waste Management
- Electrospun Nanofibers in Biomedical Applications
- Carbon and Quantum Dots Applications
- Therapeutic Uses of Natural Elements
- Occupational exposure and asthma
Ørsted (Denmark)
2020
Technical University of Denmark
2013-2020
Ramboll (Denmark)
2020
National Research Centre for the Working Environment
2014-2019
Lung deposition of multi-walled carbon nanotubes (MWCNT) induces pulmonary toxicity. Commercial MWCNT vary greatly in physicochemical properties and consequently biological effects. To identify determinants MWCNT-induced toxicity, we analyzed the effects exposure to 10 commercial (supplied three groups different dimensions, with one pristine two/three surface modified each group). We characterized morphology, chemical composition, area functionalization levels. were deposited lungs female...
Graphene and graphene oxide receive much attention these years, because they add attractive properties to a wide range of applications products. Several studies have shown toxicological effects other carbon‐based nanomaterials such as carbon black nanoparticles nanotubes in vitro vivo. Here, we report in‐depth physicochemical characterization three commercial materials, one (GO) two reduced oxides (rGO) assess cytotoxicity genotoxicity the murine lung epithelial cell line FE1. The studied GO...
Carbon nanotubes vary greatly in physicochemical properties. We compared cytotoxic and genotoxic response to 15 multiwalled carbon (MWCNT) with varying properties identify drivers of toxic responses. The studied MWCNT included OECD Working Party on Manufactured Nanomaterials (WPMN) (NM‐401, NM‐402, NM‐403), materials (NRCWE‐026 MWCNT‐XNRI‐7), three sets surface‐modified grouped by physical characteristics (thin, thick, short I–III, respectively). Each Groups I–III pristine, hydroxylated...
Environmental and human risk assessment models are critical for estimating the impact of nanomaterials on ecosystem health. Realistic exposure estimates usually require quantitative process-specific release emission characteristics in specific situation. For nanomaterial-based products, data suitable modeling currently very scarce. Consequently, this study, we reviewed literature extracted or derived releases, as well properties released fragments from 374 different scenarios products...
Some multi-walled carbon nanotubes (MWCNTs) induce mesothelioma in rodents, straight MWCNTs showing a more pronounced effect than tangled MWCNTs. As primary and secondary genotoxicity may play role MWCNT carcinogenesis, we used battery of assays for DNA damage micronuclei to compare the (MWCNT-S) (MWCNT-T) vitro (primary genotoxicity) vivo or genotoxicity). C57Bl/6 mice showed dose-dependent increase strand breaks, as measured by comet assay, lung cells 24 h after single pharyngeal...
This study investigates the impact of fatty acids on cloud condensation nuclei (CCN) activity sea salt aerosol initial size 30, 50, 70 or 90 nm. Two major in marine environment, palmitic acid (C16) and stearic (C18), were investigated along with their unsaturated analogues palmitoleic oleic acid, respectively. Sea seed particles generated by aeration through a diffuser placed inside spray tank. Fatty added to via vapours heated flask at different temperatures. The diameters CCN before after...
Poor air quality is a leading contributor to the global disease burden and total number of deaths worldwide. Humans spend most their time in built environments where majority inhalation exposure occurs. Indoor Air Quality (IAQ) challenged by outdoor pollution entering indoors through ventilation infiltration indoor emission sources. The aim this study was understand current knowledge level gaps regarding effective approaches improve IAQ. Emission regulations currently focus on emissions,...
Little is known about the exposure levels and adverse health effects of occupational to airplane emissions. Diesel exhaust particles are classified as carcinogenic humans jet engines produce potentially similar soot particles. Here, we evaluated potential risk by analyzing from a non-commercial airfield apron commercial airport. Toxicity collected was alongside NIST standard reference diesel (NIST2975) in terms acute phase response, pulmonary inflammation, genotoxicity after single...
The composition and carbon nanostructure of soot are important parameters influencing health climate effects, the efficacy mitigation technologies. We used laser-vaporization, electron-ionization aerosol mass spectrometry (or SP-AMS) to systematically investigate relationships between spectra, (HRTEM), (thermal-optical analysis) for with varying physicochemical properties. SP-AMS refractory black concentrations (based on C≤5+ clusters) were correlated elemental (r = 0.98, p < 10−8)...
The toxicity of dusts from mechanical abrasion multi-walled carbon nanotube (CNT) epoxy nanocomposites is unknown. We compared the toxic effects generated by sanding composites with and without CNT. used CNT type was included for comparison.Mice received a single intratracheal instillation 18, 54 162 μg or 54, 486 dust composite DNA damage in lung liver, inflammation liver histology were evaluated 1, 3 28 days after instillation. Furthermore, mRNA expression interleukin 6 heme oxygenase 1...
ABSTRACT In the indoor environment, people are exposed to several fungal species. Evident dampness is associated with increased respiratory symptoms. To examine immune responses exposure, mice often a single species grown on an agar medium. The aim of this study was develop inhalation exposure system be able in mixed aerosolized from fungus-infested building materials. Indoor airborne fungi were sampled and cultivated gypsum boards. Aerosols characterized compared aerosols homes. containing...
Recent findings show that cerium oxide (CeO2) nanoparticles may undergo in vivo-induced size transformation with the formation of smaller particles could result a higher translocation following pulmonary exposure compared to virtually insoluble particles, like titanium dioxide (TiO2). Therefore, we liver deposition CeO2 and TiO2 similar primary sizes 1, 28 or 180 days after intratracheal instillation 162 μg NPs female C57BL/6 mice. Mice exposed by intravenous injection oral gavage were...
A Near Field/Far Field (NF/FF) model is a well-accepted tool for precautionary exposure assessment but its capability to estimate particulate matter (PM) concentrations not well studied. The main concern related emission source characterization which as defined PM emitters compared e.g. solvents. One way characterize strength by using the material dustiness index scaled correspond industrial use modifying factors, such handling energy factors. In this study we investigate how NF/FF predicts...
This work provides insight into the morphology and mixing state of submicron particles in diesel exhaust from a ship engine with an gas recirculation scrubber. Particles this low-speed on test bed were collected using microinertial impactor transmission electron microscopy (TEM) grids two stages. Micro- nanostructural characteristics single studied by TEM. Image analysis was carried out overview high-resolution images, revealing influence treatment (scrubber) particle state. Soot...
Abstract Particulate matter (PM) air pollution is a central concern for public health. Current legislation relies on mass concentration basis, despite broad acceptance that alone insufficient to capture the complexity and toxicity of airborne PM, calling additional more comprehensive measurement techniques. We study what extent scanning electron microscopy coupled with energy dispersive X-ray spectroscopy (SEM/EDS) can be applied physicochemical characterization complex aerosols, investigate...
Nanoscale TiO2 (nTiO2) is manufactured in high volumes and of potential concern occupational health. Here, we measured workers exposure levels while ceramic honeycombs were dip coated with liquid photoactive nanoparticle suspension dried an air blade. The nTiO2 concentration used to assess process specific emission rates using a convolution theorem calculate inhalation dose deposited particles. Dip coating did not result detectable release particles but blade drying released fine-sized was...
Halloysite nanotubes (HNTs) are abundant naturally-occurring hollow aluminosilicate clay mineral fibers with a typical diameter < 100 nm and an aspect ratio of up to 200. Here we assessed the potential inhalation exposure HNTs in industrial research laboratory. Inside fume hood, ten times g were poured at rate 0.5 kg min−1, which increased concentrations from background level 2900 cm−3 6.4 μm2 cm−3. respirable mass concentration was 143 μg m−3 including particles. Outside hood did not...
Fume hoods are one of the most common types equipment applied to reduce potential particle exposure in laboratory environments. A number previous studies have shown release during work with nanomaterials under fume hoods. Here, we assessed workers' inhalation synthesis and handling CuO, TiO2 ZnO a hood. In addition, tested capacity hood prevent air simulated spillage different powders (silica fume, zirconia TZ-3Y TiO2). Airborne concentrations were measured near field, far breathing zone...
Highly porous cellulose nanofiber (CNF) aerogels are promising, environmentally friendly, reusable, and low-cost materials for several advanced environmental, biomedical, electronic applications. The have a complex hierarchical 3D network structure with pore sizes ranging from nanometers to hundreds of micrometers. morphology the has critical role on performance aerogels, but it is difficult characterize thoroughly traditional techniques. Here, we introduce combination nuclear magnetic...
The use of composites is ever increasing due to their important structural and chemical features. composite component production often involves high energy grinding sanding processes which emissions workers are potentially exposed. In this study we investigated the machining carbon glass fibre-reinforced epoxy materials at two facilities. We measured particle number concentrations size distributions released material in near field far during glass- composites. assessed means reducing...
Here, we studied the particle release rate during Electrostatic spray deposition of anatase-(TiO2)-based photoactive coating onto tiles and wallpaper using a commercially available electrostatic device. Spraying was performed in 20.3m3 test chamber while measuring concentrations 5.6nm to 31μm-size particles volatile organic compounds (VOC), as well room surfaces on gun user hand. The emission rates were quantified aerosol mass balance modelling. geometric mean number 1.9×1010s-1 381μgs-1....