A5090927295- Occupational exposure and asthma
- Asthma and respiratory diseases
- Indoor Air Quality and Microbial Exposure
- Occupational and environmental lung diseases
- Air Quality and Health Impacts
- Allergic Rhinitis and Sensitization
- Occupational Health and Safety Research
- Contact Dermatitis and Allergies
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pediatric health and respiratory diseases
- Noise Effects and Management
- Respiratory viral infections research
- Dermatology and Skin Diseases
- Neonatal Respiratory Health Research
- Food Allergy and Anaphylaxis Research
- IL-33, ST2, and ILC Pathways
- Child and Adolescent Health
- Air Quality Monitoring and Forecasting
- Tuberculosis Research and Epidemiology
- Genetic Associations and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Smoking Behavior and Cessation
- Odor and Emission Control Technologies
University of British Columbia
2011-2023
Toronto Western Hospital
2013
Vancouver General Hospital
1993-2012
University of British Columbia Hospital
2007-2012
Semmelweis University
2011
University of Hong Kong
2001-2010
Queen Mary Hospital
2001-2010
Respiratory Clinical Trials
2008
Chinese University of Hong Kong
2003-2007
Christie's
2004
Background: Severe acute respiratory syndrome (SARS) is a newly discovered disease caused by novel coronavirus. The present study studied the longitudinal profile of antibodies against SARS‐coronavirus (SARS‐CoV) in SARS patients and evaluated clinical significance these antibodies. Methods: Two methods, ELISA indirect immunofluorescent assay, were used for detection anti‐SARS‐CoV IgG IgM 335 serial sera from 98 patients. In 18 patients, serum antibody profiles investigated neutralization...
The prevalence of allergic rhinitis is high, but the role environmental factors remains unclear. We examined cohort-specific and combined associations residential greenness with aeroallergen sensitization based on individual data from Swedish (BAMSE), Australian (MACS), Dutch (PIAMA), Canadian (CAPPS SAGE), German (GINIplus LISAplus) birth cohorts (n = 13 016).Allergic (doctor diagnosis/symptoms) were assessed in children aged 6-8 years six 10-12 five cohorts. Residential was defined as mean...
SUMMARy _ Twenty-two woodworkers presenting with respiratory symptoms after exposure to the dust of western red cedar were studied. Eighteen them had bronchial reactions inhalation extract. They presented a characteristic clinical picture. After period intensive cedar, they developed nocturnal attacks cough and asthma. Later, occurred earlier during day if continued work this wood. Twelve also rhinitis. improved weekends holidays. Most recovered within 6 months cessation exposure. The...
The evidence supporting an association between traffic-related air pollution exposure and incident childhood asthma is inconsistent may depend on genetic factors.To identify gene-environment interaction effects using genome-wide single-nucleotide polymorphism (SNP) data exposure. Identified loci were further analyzed at epigenetic transcriptomic levels.We used land use regression models to estimate individual (represented by outdoor NO2 levels) the birth address performed a study for...
<h3>Background</h3> The prevalence of asthma has increased in developed countries the past 2 decades. effectiveness intervention measures on primary prevention not been well studied. <h3>Objective</h3> To assess a multifaceted program high-risk infants (in this study,<i>infants</i>are defined as persons from birth to age 1 year). <h3>Design</h3> Prospective, prenatally randomized, controlled study with follow-up through year. <h3>Setting</h3> University hospital-based settings at Canadian...
CT in silicosis: correlation with plain films and pulmonary function testsCJ Bergin, NL Muller, S Vedal M Chan-YeungAudio Available | Share
To provide broad guidelines and principles to help primary care physicians, occupational allergists respirologists with the recognition, diagnosis management of patients asthma (OA).These are mainly directed towards OA induced by a workplace sensitizing agent. However, irritant-induced aggravation underlying also addressed, some consideration is given other differential diagnoses.To enable assessing physician investigate possible appropriately for appropriate early referral when specialized...
<h3>Abstract</h3> <b>Objective:</b> To describe the outbreak of severe acute respiratory syndrome in Hong Kong. <b>Design:</b> Descriptive case series. <b>Setting:</b> Kong, Special Administrative Region, China <b>Results:</b> The started with a visitor from southern on 21 February. At hospitals where first cases were treated disease spread quickly among healthcare workers, and then out into community as family members became infected. By 1 April, 685 had been reported 16 deaths. Symptoms...
Objectives The risk of incident asthma and bronchial hyper-reactivity associated with early life exposure to traffic-related air pollution has not been fully elucidated. We aimed evaluate the hypothesis that new onset is positively in a well-characterised high-risk birth cohort. Methods Infants at for were recruited an intervention study. Birth year exposures NO, NO 2 , black carbon PM 2.5 estimated by land use regression. At 7 years age, was assessed paediatric allergist measured...
After an average follow-up of 6.5 yr (range 1 to 13), 48 68 patients with cedar asthma, who were still working in the same industry, re-examined. In all them, diagnosis asthma had been confirmed a specific challenge inhalation test plicatic acid. We graded severity symptoms and requirement for antiasthma medications at time visit. Spirometry measurement airway responsiveness methacholine (PC20 methacholine) also done on both visits. The increase or decrease symptoms, requirement, FEV1 PC20...