A5103015427- Meat and Animal Product Quality
- Protein Hydrolysis and Bioactive Peptides
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Aquaculture Nutrition and Growth
- Food Quality and Safety Studies
- Collagen: Extraction and Characterization
- Biochemical effects in animals
- Sports Performance and Training
- Food Allergy and Anaphylaxis Research
- Sports Dynamics and Biomechanics
- Uterine Myomas and Treatments
- Advanced Glycation End Products research
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Advanced biosensing and bioanalysis techniques
- Tactile and Sensory Interactions
- Winter Sports Injuries and Performance
- Food Industry and Aquatic Biology
- Physiological and biochemical adaptations
- Ubiquitin and proteasome pathways
- Lower Extremity Biomechanics and Pathologies
- Advanced Biosensing Techniques and Applications
- Identification and Quantification in Food
- Shoulder Injury and Treatment
Hokkaido University
2011-2024
Mochida Pharmaceutical (Japan)
2009-2024
Tokyo University of Agriculture and Technology
2019-2023
Novo Nordisk (Denmark)
2022
Kogakuin University
2019-2020
Shimane University
2018-2020
University of Shimane
2019-2020
University College London
2014-2018
CRUK Lung Cancer Centre of Excellence
2014-2018
Institute of Magnetism
2018
We present the physics program of Belle II experiment, located on intensity frontier SuperKEKB $e^+e^-$ collider. collected its first collisions in 2018, and is expected to operate for next decade. It anticipated collect 50/ab collision data over lifetime. This book outcome a joint effort collaborators theorists through theory interface platform (B2TiP), an that commenced 2014. The aim B2TiP was elucidate potential impacts program, which includes wide scope topics: B physics, charm, tau,...
Linear ubiquitination is crucial for innate and adaptive immunity. The linear ubiquitin chain assembly complex (LUBAC), consisting of HOIL-1, HOIP, SHARPIN, the only known ligase that generates linkages. HOIP catalytically active LUBAC component. Here, we show both constitutive Tie2-Cre-driven deletion lead to aberrant endothelial cell death, resulting in defective vascularization embryonic lethality at midgestation. Ablation tumor necrosis factor receptor 1 (TNFR1) prevents defects, death...
In the original version of this manuscript, an error was introduced on pp352. '2.7nb:1.6nb' has been corrected to '2.4nb:1.3nb' in current online and printed version. doi:10.1093/ptep/ptz106.
Abstract Catalytic allylation of aryl halides with allyltributyltin in the presence tetrakis(triphenylphosphine)palladium(O) was investigated. The reaction bromides proceeded efficiently to yield allylbenzenes.
Abstract Alkylation, arylation, and vinylation of acyl chlorides by means organotin compounds in the presence catalytic amounts tetrakis(triphenylphosphine)palladium(O) were demonstrated. The corresponding ketons obtained fairly good yields.
Concomitant hepatocyte apoptosis and regeneration is a hallmark of chronic liver diseases (CLDs) predisposing to hepatocellular carcinoma (HCC). Here, we mechanistically link caspase-8-dependent HCC development via proliferation- replication-associated DNA damage. Proliferation-associated replication stress, damage, genetic instability are detectable in CLDs before any neoplastic changes occur. Accumulated levels determine predict subsequent hepatocarcinogenesis. damage sensed by complex...
The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ligase which catalyses generation of linkages
mRNAs for cell wall-related enzymes in developing cotton fiber cells were measured by reverse transcription-PCR analysis. Both endo-l,4-β-glucanase and expansin mRNA levels high during elongation but decreased when ceased, xyloglucan decreased. The endo-l,3-β-glucanase level was very low the elongating increased gradually at onset of secondary wall synthesis, accompanying massive deposition cellulose. Endoxyloglucan transferase sucrose synthase constant all stages growth.
Abstract A histological study combined with a newly devised compression test was carried out to clarify the mechanism of post‐mortem tenderisation rainbow trout ( Oncorhyncus mykiss Walbaum) muscle. It is suggested that integrity extracellular matrix structure very important for toughness fish During chilled storage, gradual disintegration clearly demonstrated by light microscopic observations after but little change observed without it. therefore muscle closely related death.
ABSTRACT The textural degradation of oval‐filefish meat gel accompanying the increase peptides and breakdown myosin heavy chain was caused by proteinase(s) tightly associated with myofibrils. Leupeptin n‐butanol inhibited proteolytic activity to some degree. existence an endogenous inhibitor for in sarcoplasm also demonstrated.
Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) are a promising cell source to treat age-related macular degeneration (AMD). Despite several ongoing clinical studies, detailed mapping of transient cellular states during in vitro differentiation has not been performed. Here, we conduct single-cell transcriptomic profiling an hESC-RPE protocol that developed for use. Differentiation progressed through culture diversification recapitulating early development,...