A5042356780- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Body Composition Measurement Techniques
- Clinical Nutrition and Gastroenterology
- Diet and metabolism studies
- Pancreatitis Pathology and Treatment
- Diet, Metabolism, and Disease
- Liver physiology and pathology
- COVID-19 Clinical Research Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Advanced Chemical Sensor Technologies
- Drug Transport and Resistance Mechanisms
- Biochemical Analysis and Sensing Techniques
- Hepatitis B Virus Studies
- Organ Transplantation Techniques and Outcomes
- Liver Diseases and Immunity
- Frailty in Older Adults
- Heart Rate Variability and Autonomic Control
- Alcohol Consumption and Health Effects
- Hepatocellular Carcinoma Treatment and Prognosis
- Neurological Disease Mechanisms and Treatments
- Helicobacter pylori-related gastroenterology studies
- Biochemical effects in animals
- Amoebic Infections and Treatments
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2015-2024
Research Network (United States)
2021-2023
Universidad Nacional Autónoma de México
2021-2023
Hospital General de México
2021
RWTH Aachen University
2015-2020
Hospital Universitario Virgen Macarena
2016
Universidad Complutense de Madrid
2016
University of Arkansas for Medical Sciences
2016
Mayo Clinic in Arizona
2014
Sarcopenia and physical deconditioning are frequent complications in patients with cirrhosis end‐stage liver disease (ESLD). They the end result of impaired dietary intake, chronic inflammation, altered macronutrient micronutrient metabolism, low activity. Frailty is prolonged sarcopenia deconditioning. It severely affects a patient's functional status presents approximately 1 5 on transplantation waiting list. Sarcopenia, poor fitness/cardiopulmonary endurance (CPE), frailty all associated...
OBJECTIVES: Exercise has been scarcely studied in patients with cirrhosis, and prior evidence showed hepatic venous pressure gradient (HVPG) to be increased response exercise. The aim of this study was investigate the effects a supervised physical exercise program (PEP) cirrhosis. METHODS: In an open-label, pilot clinical trial, cirrhosis were randomized PEP (cycloergometry/kinesiotherapy plus nutritional therapy,n=14) or control (nutritional therapy,n=15); for 14 weeks. Primary outcomes...
The potential benefits of branched-chain amino acids (BCAAs) in cirrhosis extend beyond just the improvement nutritional status. Their effects include glucose tolerance, oxidative stress, and inflammatory markers, as has been shown several studies. A dual approach a high-protein, high-fiber diet plus BCAAs could have additional benefits, compared with alone. Such an not explored therefore aim present study was to evaluate effect combination BCAA supplementation over 6-month period time on...
BackgroundMetabolic diseases are risk factors for severe Coronavirus disease (COVID-19), which have a close relationship with metabolic dysfunction-associated fatty liver (MAFLD).AimsTo evaluate the presence of MAFLD and fibrosis in patients COVID-19 its association prognosis.MethodsRetrospective cohort study. In hospitalized COVID-19, steatosis was determined by computed tomography scan (CT). Liver assessed using NAFLD score (NFS score), when altered, AST to platelet ratio index (APRI)...
The potential benefits of branched-chain amino acids (BCAAs) in cirrhosis extend beyond just the improvement nutritional status. Their effects include glucose tolerance, oxidative stress, and inflammatory markers, as has been shown several studies. A dual approach a high-protein, high-fiber diet plus BCAAs could have additional benefits, compared with alone. Such an not explored therefore aim present study was to evaluate effect combination BCAA supplementation over 6-month period time on...
AIMEvaluate the association between phase angle and development of hepatic encephalopathy in longterm follow-up cirrhotic patients. METHODSThis was a prospective cohort study.Clinical, nutritional biochemical evaluations were performed.Mann-Whitney's U χ 2 tests used as appropriate.Kaplan-Meier curves Cox proportional Hazards analysis to evaluate prediction incidence encephalopathy. RESULTSTwo hundred twenty included; most frequent etiology cirrhosis hepatitis C infection, 52% patients...
Acute‐on‐chronic liver failure (ACLF) develops in acute decompensation (AD) of cirrhosis and shows high mortality. In critically ill patients, early diagnosis ACLF could be important for therapeutic decisions (eg, renal replacement, artificial support, transplantation). This study evaluated fibroblast growth factor 21 (FGF21) as a marker mitochondrial dysfunction the context ACLF. The included 154 individuals (112 patients 42 healthy controls) divided into training validation cohort. cohort...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a serious health problem, and recent evidence indicates that gut microbiota plays key role in its development. It known 2-oleoyl glycerol (2-OG) produced by the associated with hepatic fibrosis, but it not whether this metabolite involved development of steatosis. The aim study was to evaluate how high-fat sucrose diet (HFS) increases 2-OG production through dysbiosis identify modifies lipogenesis mitochondrial activity for...
Abstract Background & Aims Factors other than elevated levels of ammonia may be implicated in hepatic encephalopathy ( HE ) pathophysiology, including abnormal cerebral haemodynamics. Transcranial Doppler ultrasonography TCD evaluates cerebrovascular structural integrity and reactivity, through pulsatility index PI breath‐holding BHI respectively. The aim this study was to evaluate haemodynamics by patients with compensated decompensated cirrhosis, without . Methods We studied 90...
The outbreak of the novel coronavirus SARS-CoV-2 epidemic has rapidly spread and still poses a serious threat to healthcare systems worldwide. In present study, electronic medical records containing clinical indicators related liver injury in 799 COVID-19-confirmed patients admitted hospital Madrid (Spain) were extracted analyzed. Correlation between disease outcome was also evaluated. Serum levels Alanine aminotransferase (ALT), Aspartate (AST), Gamma-glutamyltransferase (GGT), Alkaline...
In patients with acute liver failure (ALF) who suffer from massive hepatocyte loss, progenitor cells (LPCs) take over key functions, which ultimately determines survival. This study investigated how the expression of nuclear factor 4α (HNF4α), its regulators, and targets in LPCs clinical outcome ALF.Clinicopathological associations were scrutinized 19 ALF (9 recovered 10 receiving transplantation). Regulatory mechanisms between follistatin, activin, HNF4α, coagulation LPC vitro...
The present review of noncaloric sweeteners (NCSs) by the Asociación Mexicana de Gastroenterología was carried out to analyze and answer some most frequent questions concerns about NCS consumption in patients with gastrointestinal disorders, through a thorough medical literature. A group gastroenterologists experts on nutrition, toxicology, microbiology, endocrinology reviewed analyzed published literature topic. working formulated conclusions, based scientific evidence published, give an...
Exercise in cirrhosis of the liver is an emerging topic hepatology. Despite known benefits exercise general population, there are currently few studies addressing that issue relation to and more evidence still needed. Even though some have reported acute, exercise-induced increase hepatic venous pressure gradient (HVPG), opposite (a decrease HVPG) has been shown by recent data after program carried out for >14 weeks. In addition benefit, improvement described metabolic profile, quality life,...
AIM:To evaluate the association between serum concentrations of S100β in patients with cirrhosis and presence low grade hepatic encephalopathy (HE). METHODS:This was a cross-sectional study.The population categorized into four groups healthy subjects, without HE, covert (CHE) overt HE.Kruskal-Wallis, Mann Whitney's U Bonferroni adjustment Spearman correlations area under ROC were used as appropriate. RESULTS:A total 61 subjects included, 46 cirrhotic 15 volunteers.S100β values different...
Objective Endoscopic retrograde cholangio-pancreatography (ERCP) is useful for the management of biliary tract diseases; in patients with cirrhosis, portal hypertension may increase risk complications from ERCP. We evaluated outcome and factors related to ERCP cirrhosis hypertension. Patients methods In this case–control study, 37 (71 procedures) (group 1) controls 2) undergoing were included. Logistic regression receiver operating characteristic curve analysis used predict factors. Results...