A5089529693- Osteoarthritis Treatment and Mechanisms
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Bone Metabolism and Diseases
- Inflammatory mediators and NSAID effects
- Medicinal Plant Pharmacodynamics Research
- Gout, Hyperuricemia, Uric Acid
- Acupuncture Treatment Research Studies
- Lower Extremity Biomechanics and Pathologies
- Growth Hormone and Insulin-like Growth Factors
- Pharmacological Effects of Natural Compounds
- Foot and Ankle Surgery
- Bone health and treatments
- Musculoskeletal pain and rehabilitation
- Urticaria and Related Conditions
- Traditional Chinese Medicine Analysis
- Mesenchymal stem cell research
- Cancer, Hypoxia, and Metabolism
- Rheumatoid Arthritis Research and Therapies
- Bone health and osteoporosis research
- Natural product bioactivities and synthesis
- Case Reports on Hematomas
- Knee injuries and reconstruction techniques
- Plant-based Medicinal Research
- Phytochemical Studies and Bioactivities
Fujian University of Traditional Chinese Medicine
2014-2025
Johns Hopkins University
2007
Based on ultra-high performance liquid chromatography-quadrupole-Exactive Orbitrap mass spectrometry(UPLC-Q-Exactive Orbitrap-MS) technology and network pharmacology, this study explored the pharmacodynamic substances potential mechanisms of Huazhuo Sanjie Chubi Decoction in treatment gouty arthritis(GA). UPLC-Q-Exactive Orbitrap-MS was used to identify components Decoction, qualitative analysis its active ingredients carried out, with a total 184 identified. A 897 ingredient targets were...
Abstract Background It is becoming increasingly necessary for community health centers to make rehabilitation services available patients with osteoarthritis of the knee. However, a number reasons, including lack expertise, small size and availability only simple medical equipment, conventional therapy has not been widely used in China. Consequently, most knee seek treatment high-grade hospitals. many cannot manage techniques that they were taught hospital. Methods such as acupuncture, tuina...
Objective: To examine the effect and mechanism of Strychnine total alkaloids on a model knee osteoarthritis. Methods: New Zealand rabbits were randomly divided into normal group, alkaloid high/medium/low dose groups sodium hyaluronate group. Except for control all other injected with papain in joint cavity to establish After 8 weeks modeling, high, medium low alkaline was given by injection cavity, 0.3 ml, 0.2 0.1 ml respectively. At this time an intra-articular also The continually...
This study aims to explore the mechanism of Zhuanggu Jianxi Decoction in reducing synovial tissue inflammation human knee osteoarthritis(KOA) via liver X receptors(LXRs)/nuclear factor(NF)-κB signaling pathway. The samples were collected from 5 healthy volunteers and 30 KOA synovitis patients cultured vitro. heathy set as normal group, those randomized into synovitis, Decoction, LXRα inhibitor, N-CoR inhibitor groups. groups treated with 10% blank serum, drug-containing serum+LXRα...
Background: Acupuncture and moxibustion are traditional Chinese medicine therapies commonly used to treat knee osteoarthritis (KOA). Although acupoint selection affects the effectiveness of acupuncture moxibustion, basic rules little understood there is a lack guidelines regarding prescription. In this study, we data mining approaches investigate principles provide framework for formulation prescription in clinical treatment KOA.Materials Methods: PubMed, Cochrane Library, Science Citation...
Background: Acupuncture and moxibustion are traditional Chinese medicine therapies commonly used to treat knee osteoarthritis
 (KOA). Although acupoint selection affects the effectiveness of acupuncture moxibustion, basic rules selection
 little understood there is a lack guidelines regarding prescription. In this study, we data mining approaches to
 investigate principles provide framework for formulation prescription in and
 clinical treatment KOA.
 Materials...