Enhanced neuroinflammation is an important mechanism underlying perioperative neurocognitive disorders. Regulatory T cells (Tregs) play a crucial role in regulating systemic immune responses. The present study was aimed to investigate the participation of Tregs development postoperative cognitive dysfunction (POCD).Surgery-associated disorder induced 18-month-old mice subjected internal fixation tibial fracture. Morris water maze used examine function. Splenic were collected for RNA...

Adjuvant endocrine therapy (AET) is essential for improving survival and reducing mortality recurrence rates in breast cancer (BrCa) patients. However, the adherence to AET among BrCa patients poor, there no scale measure or reasons non-adherence mainland China. The aim of this study was assess psychometric properties simple Chinese version Medication Adherence Reasons (MAR) undergoing AET. This utilized a cross-sectional research design with two phases: (1) translation cross-cultural...

Background: Urothelial carcinoma (UC) is the most common type of bladder malignancy. Although majority UC present as non-invasive tumors, a subset them progress into invasive cancer and cause significant morbidity mortality. Objective: In this study, we examined association between tumor mitotic activity associated progression high-grade papillary bladder. Methods: Forty-four cases tumors that met selection criteria were retrieved from Department Pathology archives, and, for each case,...

This study constructs an acupuncture knowledge graph (AcuKG) to systematically organize and represent acupuncture-related in a structured scalable format. By extracting integrating from diverse data sources, covering indication, treatment efficacy, practice guidelines, clinical research etc., AcuKG enhances discovery utilization while improving interoperability the field of acupuncture. To achieve this, we employ multiple methods, including entity recognition, term normalization, semantic...

Carbon isotope logging technology can obtain timely and accurate hydrocarbon fluid reservoir geological information has great application potential in oil–gas body property analysis, the comprehensive study of source rocks, fault-sealing evaluation. Since 2014, real-time methane been applied western South China Sea. Based on on-site, real-time, continuous, detection carbon isotopes, combined with rapid analysis evaluation gas measurement data, effect ultra-high-temperature high-pressure...

To investigate the feasibility of ultra-low-dose CT (ULDCT) reconstructed with artificial intelligence iterative reconstruction (AIIR) algorithm in total-body PET/CT imaging.The study included both phantom and clinical parts. An anthropomorphic underwent imaging ULDCT (10mAs) standard-dose (SDCT) (120mAs), respectively. was AIIR hybrid (HIR) (expressed as ULDCT-AIIRphantom ULDCT-HIRphantom), respectively, SDCT HIR (SDCT-HIRphantom) control. In part, 52 patients malignant tumors scan....

Abstract Background Telocytes (TCs) are newly identified interstitial cells that participate in tissue protection and repair. The present study investigated the mechanisms underlying protective effect of TCs a mouse model respiratory distress. Methods acute distress syndrome (ARDS) was established by intratracheal instillation lipopolysaccharide (LPS). After culture medium, lung injury assessed, angiogenesis markers, including CD31 endothelial nitric oxide synthase (eNOS), were detected...

Abstract Background. Cancer-related fatigue (CRF) is a subjective and distressing symptom, its associated factors in developing countries remain ambiguous. The goal of this study was to determine the prevalence with CRF among cancer patients China. Methods. This designed as cross-sectional eastern China, regardless their diagnoses. Data were collected by using questionnaire survey (including demographic information brief inventory) after informed written consent obtained. A chi-square test...

Introduction Benign paroxysmal positional vertigo (BPPV) is recognised as the leading cause of peripheral in adults. The canalith repositioning procedure (CRP) can be used for effective treatment BPPV. However, some patients experience residual dizziness (RD) even after successful CRP, resulting a significant negative impact on their daily function and quality life. Exercise-based vestibular rehabilitation (VR) has been proven an method managing applied with various disorders. efficacy VR to...

Abstract Aim The purpose of this study was to investigate the safety clinically indicated peripheral intravenous catheters (PIVC) replacement intervals. Background Peripheral are used internationally, including in China where PIVCs routinely replaced every 72 96 hours. Despite some recent international evidence showing such routine is unnecessary, developing countries as have no supporting data. Method This cluster‐randomized trial conducted between December 2 and 31, 2013, 10 internal...

Abstract It remains challenging to predict the risk of rupture for a specific atherosclerotic plaque timely, thrombotic trigger tightly linked inflammation. CD11b, is biomarker abundant on inflammatory cells, not restricted monocytes/macrophages. In this study, we fabricated probe named as 99m Tc-MAG 3 -anti-CD11b detecting inflamed plaques with single photon emission computed tomography/computed tomography (SPECT/CT). The ApoE-knockout (ApoE −/− ) mice were selected establish animal models,...

Abstract Background It is becoming increasingly necessary for community health centers to make rehabilitation services available patients with osteoarthritis of the knee. However, a number reasons, including lack expertise, small size and availability only simple medical equipment, conventional therapy has not been widely used in China. Consequently, most knee seek treatment high-grade hospitals. many cannot manage techniques that they were taught hospital. Methods such as acupuncture, tuina...

The purpose of this study was to explore the cortical deficits patients with acquired concomitant esotropia (AACE) using resting-state functional magnetic resonance imaging (rs-fMRI) technique.Rs-fMRI signals from 25 AACE and matched controls were collected. repeated-measures analysis variance (RM-ANOVA) test two-sample t-test used investigate statistical differences amplitudes low-frequency fluctuation (ALFF) correlation performed validate relationship signal change clinical features.The...

Objective To evaluate the effects of heparin saline versus normal as locking solution for maintaining patency in peripheral venous catheters Chinese patients. Methods This open-label, randomized controlled study was conducted two hepatobiliary surgery wards, where patients received identical treatments, at a tertiary referral hospital. Patients were randomly divided into group (NS, 3 ml) or (HS, 50 IU/ml, catheter sealing. Results The enrolled 286 and 609 included analysis. groups had no...

Communication with children is a major concern for mothers breast cancer. Chinese people have specific understanding of cancer and death, which may affect their way communication.The aim this study to explore how communicate about illness children.An interpretive description was conducted. Forty nonterminal in mainland China were interviewed individually. The data analyzed using 3 steps coding: free coding, descriptive coding.Four themes identified: breaking the news, explaining children,...

Examine the content of children's books and summarize main issues related to communication with young children about maternal cancer, especially breast cancer.A search English discussing early-stage (breast) cancer written for aged 3-12 years was conducted on Amazon.com Web site. Each 45 identified analyzed independently by two three coders using inductive qualitative analysis.The contents these included cancer-related knowledge, impacts coping strategies. The concept its treatment...