A5024645553- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Veterinary Equine Medical Research
- Genetic Mapping and Diversity in Plants and Animals
- Wildlife Ecology and Conservation
- Bat Biology and Ecology Studies
- Reproductive Physiology in Livestock
- Animal Ecology and Behavior Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- melanin and skin pigmentation
- Microbial infections and disease research
- Animal Genetics and Reproduction
- Botanical Studies and Applications
- Wnt/β-catenin signaling in development and cancer
- Meat and Animal Product Quality
- Chromosomal and Genetic Variations
- Animal Nutrition and Physiology
- Animal Diversity and Health Studies
- Genomics and Phylogenetic Studies
- Skin and Cellular Biology Research
- Identification and Quantification in Food
- Plant and fungal interactions
- Molecular Biology Techniques and Applications
- Biochemical and Structural Characterization
- Animal Disease Management and Epidemiology
Texas A&M University
2014-2024
McGill University
2014
Agriculture and Agri-Food Canada
2012
University of Saskatchewan
2012
University of Lisbon
2006-2007
University of Kentucky
1994-2006
University of Pennsylvania
1993
Texas Biomedical Research Institute
1983-1990
Savannah River National Laboratory
1983-1988
Michigan United
1986
Intense selective pressures applied over short evolutionary time have resulted in homogeneity within, but substantial variation among, horse breeds. Utilizing this population structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-specific targets of selection were identified using an FST-based statistic calculated 500-kb windows across the genome. A 5.5-Mb region ECA18, which myostatin (MSTN) gene was centered, contained highest signature both Paint Quarter...
Horses were domesticated from the Eurasian steppes 5,000–6,000 years ago. Since then, use of horses for transportation, warfare, and agriculture, as well selection desired traits fitness, has resulted in diverse populations distributed across world, many which have become or are process becoming formally organized into closed, breeding (breeds). This report describes a genome-wide set autosomal SNPs 814 36 breeds to provide first detailed description equine breed diversity. FST calculations,...
Abstract We have briefly reviewed types of genetic variation and selection in the wild as contrasted with captive populations, along objectives breeding programs, before recommending procedures for management populations. Although some inadvertent tameness adaptation to environments is inevitable any that actively applied populations should clearly defined objectives. Much apparent disagreement about probably stems from varying different programs. Objectives differ depending on whether are:...
Summary For centuries, domestic horses have represented an important means of transport and served as working companion animals. Although their role in transportation is less today, many horse breeds are still subject to intense selection based on pattern locomotion. A striking example such a selected trait the ability perform additional gaits other than common walk, trot gallop. Those could be four‐beat ambling gaits, which particularly smooth comfortable for rider, or pace, used mainly...
We constructed a 400K WG tiling oligoarray for the horse and applied it discovery of copy number variations (CNVs) in 38 normal horses 16 diverse breeds, Przewalski horse. Probes on array represented 18,763 autosomal X-linked genes, intergenic, sub-telomeric chrY sequences. identified 258 CNV regions (CNVRs) across all autosomes, chrX chrUn, but not chrY. CNVs comprised 1.3% genome with chr12 being most enriched. American Miniature had highest Quarter Horses lowest relation to Thoroughbred...
Summary There are three native Portuguese horse breeds: Lusitano, Sorraia and Garrano. This study compares diversity patterns of 17 protein 12 microsatellite markers in these as well 30 other breeds to infer relationships among the compare levels polymorphism for use conservation efforts. The Garrano Lusitano showed a high level genetic diversity, similar that observed most analysed breeds, while Friesian low variation both marker types. combined data produced tree fit historical records...
The Arabian horse ignites imagination throughout the world. Populations of this breed exist in many countries, and recent genetic work has examined diversity ancestry a few these populations isolation. Here, we explore 7 different Arabians represented by 682 horses. Three are Middle Eastern from near historical origin breed, including Syrian, Persian, Saudi Arabian. remaining Western found Europe (the Shagya Polish Arabian) America (American Arabian). Analysis structure was carried out using...
This study aims to examine the genetic structure and diversity levels of seven indigenous Greek horse breeds: Andravida, Pindos, Thessaly, Skyros, Penia, Messara Rodos, using 15 microsatellites. Phenotypic traits were combined with factorial correspondence analyses create two datasets: one “Baseline” containing typical samples, “Unknown” non-typical or disputed origin samples. In horses, 142 alleles found. The mean observed effective number alleles, polymorphism information content allelic...
Fossil records, archaeological proofs, and historical documents report that horses persisted continuously in the Iberian Peninsula since Pleistocene were taken to American continent (New World) 15th century. To investigate variation within mitochondrial DNA (mtDNA) control region of New World horse breeds, analyze their relationships, test origin horses, a total 153 samples, representing 30 analyzed by sequencing mtDNA fragments. Fifty-four haplotypes found assigned seven haplogroups....
The relationship between inbreeding and both conception foaling rates in Standardbred horses (trotters pacers) was examined for 1194 breeding years. There a statistically significant (P<0.05) trend to decrease with increased inbreeding; however, this accounted less than 2 percent of the variation. Additionally, reproductive performance not consistent trotters pacers. For (F = 0.103) there an increase inbreeding, while pacers 0.074), decreased breeding. Overall, does appear be factor...
The Sorraia horse is a closed breed with reduced effective population size and considered in critical maintained risk status. exists 2 main breeding populations, one Portugal Germany, smaller size. A set of 22 microsatellite loci was used to examine genetic diversity structure the compare individual inbreeding coefficient F, estimated from pedigree data, heterozygosity mean d2. shows lower levels when compared other breeds. Due management strategies, there are clear differences populations....
Maternal inheritance is an essential point in Arabian horse population genetics and strains classification. The mitochondrial DNA (mtDNA) sequencing a highly informative tool to investigate maternal lineages. We sequenced the whole mtDNA D-loop of 251 horses study genetic diversity phylogenetic relationships populations examine traditional strain classification system that depends on family lines using native from Middle East. variability upstream region revealed additional differences among...
The goal of the First International Equine Gene Mapping Workshop, held in 1995, was construction a low density, male linkage map for horse. For this purpose, Horse Reference Family Panel (IHRFP) established, consisting 12 paternal half‐sib families with 448 offspring provided by 10 laboratories. Blood samples were collected and DNA extracted each laboratory sent to Lexington (KY, USA) dispatch aliquots 14 typing In total, 161 markers (144 microsatellites, seven blood groups proteins) tested...
Levels of stored body fat, based upon the kidney fat index, were measured for 238 pregnant white-tailed deer through gestation period and 866 nonpregnant female breeding season. The collected on Savannah River Plant (SRP) near Aiken, South Carolina. percentage decreased significantly over length pregnancy. rate loss was related to number in utero fetuses, conception date, individual genic heterozygosity but not age, weight, or habitat (either swamp upland). Greatest females with two fetuses...
Summary The domestic horse ( Equus caballus ) was re‐introduced to the Americas by Spanish explorers. Although horses from other parts of Europe were subsequently introduced, some New World populations maintain characteristics ascribed their heritage. southeastern United States has a history invasion and settlement, this influence on local feral includes two feral‐recaptured breeds: Florida Cracker Marsh Tacky, both which are classified as Colonial horses. Banker found islands off coast...
Abstract STRUCTURE remains the most applied software aimed at recovering true, but unknown, population structure from microsatellite or other genetic markers. About 30% of ‐based studies could not be reproduced ( Molecular Ecology , 21, 2012, 4925). Here we use a large set data 2,323 horses 93 domestic breeds plus Przewalski horse, typed 15 microsatellites, to evaluate how program settings impact estimation optimal number clusters K opt that best describe observed data. Domestic are suited...
Genetic variation in Zemaitukai horses was investigated using mitochondrial DNA (mtDNA) sequencing. The study performed on 421 bp of the control region, which is known to be more variable than other sections genome. Samples from each remaining maternal family lines and three random samples for Lithuanian (Lithuanian Heavy Draught, large type) ten European horse breeds were sequenced. Five distinct haplotypes obtained five families supporting pedigree data. minimal difference between two...
As part of the requirements Convention on Biological Diversity, Canada has been investigating genetic diversity its native equine and pony populations. Along with examining four indigenous Canadian populations (Canadian horse, Lac La Croix pony, Newfoundland Sable Island population), another 10 Mountain Moorland, three Nordic, horse two feral (thought to have influenced some breeds) were also investigated. In total, 821 individuals genotyped at 38 microsatellite loci. Results analysis...
A 378-bp section of the mitochondrial displacement loop was used to estimate genetic diversity in native Canadian equine populations. The inclusion 10 Mountain and Moorland, 3 Nordic pony breeds, 2 feral populations, 5 horse breeds were also investigated as they may have influenced development (or rejuvenation) total 281 samples sequenced, which produced 75 haplotypes derived from 54 informative sites. On further investigation, 36 these found be previously unreported. Overall, lowest Sable...
Summary A panel of horse‐mouse heterohybridoma cells was tested for genetic markers using biochemical and polymerase chain reaction‐(PCR‐) based tests. Biochemical included phospho‐glucomutase ( PGM ), glucose phosphate isomerase GPI ) 6‐phosphogluconate dehydrogenase PGD ). Markers detected PCR‐based tests microsatellite HTG2–15, HMS 1–3, 5–8, VHL20, ECA2 genes equine major histocompatibility gene ELA‐DRA , tumour necrosis factor alpha (TNFA) transferrin. The results were analysed...
This study was the first to analyze polymorphic characteristics of a wide range genetic markers in three Lithuanian horse breeds. Genetic variation at seven red blood cell alloantigen (blood group) loci, 10 biochemical loci and 16 microsatellites examinated 31 Zemaitukai, 30 large-type Zemaitukai 24 Heavy Draught compared that other domestic variability breeds based upon groups higher than average for For microsatellite also high mean breeds; however, breed, levels were very near horses.
Journal Article Genic Differentiation and Evolution in the Ground Squirrel Subgenus Ictidomys (Genus Spermophilus) Get access E. Gus Cothran, Cothran Department of Zoology, University Oklahoma, Norman, Oklahoma 73069Department Biological Basic Health Sciences Human Genetics Center, North Texas State University, Denton, 76203Department Medicine, Northwestern Medical School, Chicago, Illinois 60611 Search for other works by this author on: Oxford Academic Google Scholar Earl G. Zimmerman,...