A5101426031- Chronic Lymphocytic Leukemia Research
- Genomics and Phylogenetic Studies
- Gas Sensing Nanomaterials and Sensors
- Advanced Sensor and Energy Harvesting Materials
- Analytical Chemistry and Sensors
- Monoclonal and Polyclonal Antibodies Research
- Geothermal Energy Systems and Applications
- Lymphoma Diagnosis and Treatment
- Tactile and Sensory Interactions
- Conducting polymers and applications
- Graphene research and applications
- Advanced Breast Cancer Therapies
- Soil and Unsaturated Flow
- Ferroelectric and Negative Capacitance Devices
- Climate change and permafrost
- Graphene and Nanomaterials Applications
- Acute Myeloid Leukemia Research
- Molecular Biology Techniques and Applications
- Supercapacitor Materials and Fabrication
- Advanced biosensing and bioanalysis techniques
- Building materials and conservation
- Advancements in Battery Materials
- Cultural Heritage Materials Analysis
- Cancer-related molecular mechanisms research
- Phagocytosis and Immune Regulation
Institute of Hematology & Blood Diseases Hospital
2014-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2024
Weihai Science and Technology Bureau
2024
Geological Exploration Institute of Shandong Zhengyuan
2023-2024
Beijing University of Chemical Technology
2024
University of Jinan
2019-2023
China North Industries Group Corporation (China)
2023
Shandong University
2019-2022
Northeast Electric Power University
2021-2022
Yanbian University
2021
Abstract The BIG Data Center at Beijing Institute of Genomics (BIG) the Chinese Academy Sciences provides freely open access to a suite database resources in support worldwide research activities both academia and industry. With vast amounts omics data generated ever-greater scales rates, is continually expanding, updating enriching its core through big-data integration value-added curation, including BioCode (a repository archiving bioinformatics tool codes), BioProject biological project...
Abstract The past several decades have witnessed great progress in high‐performance field effect transistors (FET) as one of the most important electronic components. At same time, due to their intrinsic advantages, such multiparameter accessibility, excellent electric signal amplification function, and ease large‐scale manufacturing, FET tactile sensors for flexible wearable devices, artificial intelligence, Internet Things, other fields perceive external stimuli has also attracted...
Manufacture of uniform, sensitive, and durable microtextured sensing materials is one the greatest challenges for pressure sensors electronic skins. Reported in this article a gold nanoparticle-assembled, 3D-interconnected, graphene microchannel-embedded PDMS (3D GMC-PDMS) film strain sensors. The consists porous nickel foam with its inner walls coated by multilayer graphene. Embedding etching removal Ni yields 3D GMC-PDMS. Coating Au nanoparticles an nanoparticle-assembled GMC-PDMS...
Abstract Background The use of ionic liquids (ILs) to fractionate lignocelluloses for various bio-based chemicals productions is in the ascendant. On this basis, protic ILs consisting triethylammonium hydrogen sulfate ([TEA][HSO 4 ]) possessed great promise due low price, pollution, and high efficiency. In study, microwave-assistant [TEA][HSO ] fractionation process was established corn stover fractionation, so as facilitate monomeric sugars production supported downstream...
Obtaining complete gene structures is one major goal of genome assembly. Some regions are fragmented in low quality and high-quality assemblies. Therefore, new approaches needed to recover regions. Genomes widely transcribed, generating messenger non-coding RNAs. These widespread transcripts can be used scaffold genomes transcribed We present P_RNA_scaffolder, a fast accurate tool using paired-end RNA-sequencing reads genomes. This aims improve the completeness both protein-coding genes....
Abstract As "molecular bridge," coupling agents can not only realize the covalent connection of composites, but also affect their properties, thus affecting properties devices based on them. Herein, leveraging differences in charge conduction (3‐aminopropyl)trimethoxysilane and 5,10,15,20‐tetrakis(4‐aminophenyl)‐21H,23H‐porphine caused by conjugacy structural differences, two kinds layer‐by‐layer assembled smart carbon materials with different electrical are obtained at same reduction...
Bone marrow mesenchymal stem cells (BMSCs) are suggested as candidates for neurodegeneration therapy by autologous to overcome the lack of neural in adults. However, differentiation BMSCs into functional neurons is a major challenge neurotherapy. Herein, methodology has been proposed induce neuronal on conductive three-dimensional graphene framework (GFs) combined with rotating magnetic field. A wireless electrical signal about 10 μA can be generated surface GFs cutting field lines based...
Abstract In the past few decades, a series of research, restoration and protection have been performed on ancient murals in Mogao Grottoes. These treatments played significant roles conservation elegant art Dunhuang. But whether reinforcement are still active which materials more appropriate remain unknown. issues crucial for murals. On-site investigation Grottoes has carried out. The purpose this is to examine renewed diseases repaired before. It will also provide useful information about...
New carbon-loaded nickel chalcogenide electrode materials (NiS2/GO and NiSe2/rGO) have been synthesized through an easy-to-operate process: NiSe2 was obtained based on NiS2 hollow spheres, successfully with l-cysteine assistance under the hydrothermal method at 120 °C. GO of different mass fraction added together l-cysteine. The electrochemical performance NiS2/GO NiSe2/rGO has greatly improved because formation a layer effectively increased specific surface area reduced charge transport...
Teleosts have more types of chromatophores than other vertebrates and the genetic basis for pigmentation is highly conserved among vertebrates. Therefore, teleosts are important models to study mechanism pigmentation. Although functional genes variations been studied, mechanisms different skin coloration remains poorly understood. The koi strain common carp has various colors patterns, making it a good model studying We performed RNA-sequencing red white identified 62 differentially...
Event camera, a novel bio-inspired vision sensor, has drawn lot of attention for its low latency, power consumption, and high dynamic range. Currently, overfitting remains critical problem in event-based classification tasks Spiking Neural Network (SNN) due to relatively weak spatial representation capability. Data augmentation is simple but efficient method alleviate improve the generalization ability neural networks, saliency-based methods are proven be effective image processing field....
Abstract The abnormal expression of a microRNA (miRNA) is associated with many major diseases. Therefore, the stability, reliability, and sensitivity miRNA detection are paramount importance for early diagnosis therapeutics. Field‐effect transistor (FET) devices, as sensors, have advantages, including their multiparameter accessibility ease large‐scale manufacturing, but electrical signals most FETs vulnerable in humid environments over extended periods time, further limiting sensing...
Recovering the gene structures is one of important goals genome assembly. In low-quality assemblies, and even some high-quality certain regions are still incomplete; thus, novel scaffolding approaches required to complete regions.We developed an efficient fast method called PEP_scaffolder, using proteins scaffold genomes. The pipeline aims recover protein-coding structures. We tested on human contigs; UniProt as guides, improvement N50 size was 17% increase with accuracy ∼97%. PEP_scaffolder...
2550 Background: IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion that exerts dual-mechanism antitumor activity via engagement of activating tumor cell phagocytosis and stimulating T-cell anti-tumor responses by binding CD47 on membrane. displays promising preclinical characteristics regarding its receptor occupancy/tumor exposure/efficacy relationship. Unlike anti-CD47 monoclonal antibodies, shows unique property weak erythrocyte conjugation so as avoiding...
In this paper, a core-shell structure nickel disulfide and ZIF-67 composite electrode material (NiS2/ZIF-67) was synthesized by two-step method. Firstly, spherical NiS2 hydrothermal method, dispersed in methanol, then reacted coated adding cobalt ions 2-methylimidazole to obtain the NiS2/ZIF-67 composite. The shows high specific capacitance (1297.9 F g-1 at 1 A g-1) excellent cycling durability (retaining 110.0% after 4000 cycles 5 g-1). Furthermore, corresponding hybrid supercapacitor...
Ivosidenib, an isocitrate dehydrogenase 1 (