- Mechanical Behavior of Composites
- Metal Forming Simulation Techniques
- Microstructure and mechanical properties
- Electronic Packaging and Soldering Technologies
- High-Velocity Impact and Material Behavior
- Metallurgy and Material Forming
- Advanced Materials and Mechanics
- Mechanical stress and fatigue analysis
- Material Properties and Processing
- Numerical methods in engineering
- Composite Material Mechanics
- Nonlocal and gradient elasticity in micro/nano structures
- Metallic Glasses and Amorphous Alloys
- Advanced Surface Polishing Techniques
- Fatigue and fracture mechanics
- Elasticity and Material Modeling
- Vibration and Dynamic Analysis
- Advanced Mathematical Modeling in Engineering
- Advanced Sensor and Energy Harvesting Materials
- Adhesion, Friction, and Surface Interactions
- Composite Structure Analysis and Optimization
- Surface Modification and Superhydrophobicity
- Drilling and Well Engineering
- High Temperature Alloys and Creep
- Polymer crystallization and properties
Gannan Medical University
2022-2025
Institute of High Performance Computing
2015-2024
Agency for Science, Technology and Research
2015-2024
University of Chinese Academy of Sciences
2024
A*STAR Graduate Academy
2017
Xi'an Polytechnic University
2016
National University of Singapore
2001-2010
Nanjing University of Aeronautics and Astronautics
2006
Tsinghua University
1993-2001
Dalian University of Technology
1990
We perform atomistic simulations on the fracture behavior of two typical metallic glasses, one brittle (FeP) and other ductile (CuZr), show that in FeP glass is governed by an intrinsic cavitation mechanism near crack tips contrast to extensive shear banding CuZr glass. a high degree atomic scale spatial fluctuations local properties main reason for observed Our study corroborates with recent experimental observations nanoscale cavity nucleation found surfaces glasses provides important...
Intestinal immune dysregulation is strongly linked to the occurrence and formation of tumors. RING finger protein 128 (RNF128) has been identified play distinct immunoregulatory functions in innate adaptive systems. However, physiological roles RNF128 intestinal inflammatory conditions such as colitis colorectal cancer (CRC) remain controversial. To elucidate function mechanism CRC. Animal models dextran sodium sulfate (DSS)-induced azoxymethane (AOM)/DSS-induced CRC were established WT...
China has the world's largest reserves of rare earth elements (REEs), but widespread mining and application REEs led to an increased risk potential pollution. Yttrium (Y), first heavy be discovered, poses a substantial threat human health. Unfortunately, little attention been given impact Y on reproductive In this study, we investigated toxic effects YCl3 mouse testes four types testicular cells, including Sertoli, Leydig, spermatogonial spermatocyte cells. The results showed that exposure...
We simulate and analyze the instability of wrinkles creases in highly deformable soft materials using a robust method point perturbation free surfaces. This enables us to identify distinct regimes wrinkle crease such as elastomers hydrogels, ascertain critical conditions for onset these two modes instability. Furthermore, we show wide range that encompasses Biot's linear stability analysis on surface beyond. approach provides practical route experimentalists their investigations...
Abstract IFN regulatory factor 7 (IRF7) exerts anti-infective effects by promoting the production of IFNs in various bacterial and viral infections, but its role highly morbid fatal Candida albicans infections is unknown. We unexpectedly found that Irf7 gene expression levels were significantly upregulated tissues or cells after C. infection humans mice IRF7 actually exacerbates independent classical function inducing production. Compared to controls, Irf7−/− showed stronger phagocytosis...
Candida albicans is among the most prevalent invasive fungal pathogens for immunocompromised individuals and novel therapeutic approaches that involve immune response modulation are imperative. Absent in melanoma 2 (AIM2), a pattern recognition receptor DNA sensing, well recognized its involvement inflammasome formation crucial role safeguarding host against various pathogenic infections. However, of AIM2 defense C. infection remains uncertain. This study reveals gene expression induced...