A5073474384- Mycotoxins in Agriculture and Food
- Probiotics and Fermented Foods
- Wheat and Barley Genetics and Pathology
- Listeria monocytogenes in Food Safety
- Iron Metabolism and Disorders
- Carcinogens and Genotoxicity Assessment
- Plant Pathogens and Fungal Diseases
- Heavy Metal Exposure and Toxicity
- Plant Disease Resistance and Genetics
- Agriculture, Plant Science, Crop Management
- Trace Elements in Health
- Gut microbiota and health
University of Aberdeen
2017-2023
ABSTRACT Mycotoxin contamination of cereal grains causes well-recognized toxicities in animals and humans, but the fate plant-bound masked mycotoxins gut is less well understood. Masked have been found to be stable under conditions prevailing small intestine are rapidly hydrolyzed by fecal microbiota. This study aims assess hydrolysis mycotoxin deoxynivalenol-3-glucoside (DON3Glc) microbiota different regions porcine intestinal tract. Intestinal digesta samples were collected from jejunum,...
Cereal foods are commonly contaminated with multiple mycotoxins resulting in frequent human mycotoxin exposure. Children at risk of high-level exposure because their high cereal intake relative to body weight. Hence, this study aims assess multimycotoxin UK children using urinary biomarkers. Spot urines (n = 21) were analyzed for multimycotoxins (deoxynivalenol, DON; nivalenol, NIV; ochratoxin A, OTA; zearalenone, ZEN; α-zearalenol, α-ZEL; β-zearalenol, β-ZEL; T-2 toxin, T-2; HT-2 HT-2; and...
Small grain cereals are frequently infected with mycotoxigenic Fusarium fungi. Oats have a particularly high risk of contamination type A trichothecene mycotoxins; their glucoside conjugates also been reported. Agronomy practices, cereal variety and weather conditions suggested to play role in infection oats. The current study investigates concentrations free conjugated mycotoxins organic conventional oats grown Scotland. In 2019, 33 milling oat samples (12 organic, 21 conventional) were...
Fusarium mycotoxins are common contaminants in cereals and often co-occur with plant-derived mycotoxin sugar conjugates. Several of these modified not degraded the small intestine hence carried through to large where microbial transformation may occur. This study aims assess gastrointestinal stability trichothecenes HT-2 toxin (HT-2), HT-2-β-glucoside (HT-2-Glc), diacetoxyscirpenol (DAS), DAS-α-glucoside (DAS-Glc) fumonisin B1 (FB1), N-(1-deoxy-d-fructos-1-yl) fumonisin-B1 (NDF-FB1). All...
Mycotoxins are important food contaminants that commonly co-occur with modified mycotoxins such as mycotoxin-glucosides in contaminated cereal grains. These masked less toxic, but their breakdown and release of unconjugated has been shown by mixed gut microbiota humans animals. The role different bacteria hydrolysing is unknown, this study therefore investigated fourteen strains human for ability to break down mycotoxins. Individual bacterial were incubated anaerobically...
Fe deficiency is relatively common in pregnancy and has both short- long-term consequences. However, little known about the effect on metabolism of other micronutrients. A total fifty-four female rats were fed control (50 mg Fe/kg) or Fe-deficient diets (7·5 mg/kg) before during pregnancy. Maternal liver, placenta fetal liver collected at day 21 for Cu Zn analysis to measure expression major genes metabolism. levels increased maternal (P=0·002) (P=0·018) rats. (P<0·0001) decreased...
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