A5033030062- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- Mass Spectrometry Techniques and Applications
- Fungal Biology and Applications
- Plant Disease Resistance and Genetics
- Plant-Microbe Interactions and Immunity
- Microbial Natural Products and Biosynthesis
- Plant and fungal interactions
- Marine Toxins and Detection Methods
- Nicotinic Acetylcholine Receptors Study
- Phytochemistry and Bioactivity Studies
- Fungal and yeast genetics research
- Mycorrhizal Fungi and Plant Interactions
- Insect and Pesticide Research
- Analytical Chemistry and Chromatography
- Advanced Proteomics Techniques and Applications
- Sphingolipid Metabolism and Signaling
- Electrohydrodynamics and Fluid Dynamics
- Ion-surface interactions and analysis
- Pesticide Residue Analysis and Safety
- Insect Resistance and Genetics
- Plant Disease Management Techniques
- Essential Oils and Antimicrobial Activity
- Marine and coastal ecosystems
- Enzyme Structure and Function
National Center for Agricultural Utilization Research
2016-2025
Agricultural Research Service
2015-2025
United States Department of Agriculture
2009-2022
Illinois Department of Agriculture
2012-2020
Peoria campus of the University of Illinois System
2018
Canada Grain Commission
2016
Nepal Agricultural Research Council
2008
Michigan State University
2008
Medical University of South Carolina
1994-2004
NOAA National Ocean Service
1999-2003
Trichothecenes are a family of terpenoid toxins produced by multiple genera fungi, including plant and insect pathogens. Some trichothecenes the fungus Fusarium among mycotoxins greatest concern to food feed safety because their toxicity frequent occurrence in cereal crops, trichothecene production contributes pathogenesis some species on plants. Collectively, fungi produce over 150 analogs: i.e., molecules that share same core structure but differ patterns substituents attached structure....
Scientific communication is facilitated by a data-driven, scientifically sound taxonomy that considers the end-user's needs and established successful practice. In 2013, Fusarium community voiced near unanimous support for concept of represented clade comprising all agriculturally clinically important species, including F. solani species complex (FSSC). Subsequently, this was challenged in 2015 one research group who proposed dividing genus into seven genera, FSSC described as members...
Accurate species-level identification of an etiological agent is crucial for disease diagnosis and management because knowing the agent's identity connects it with what known about its host range, geographic distribution, toxin production potential. This particularly true in publishing peer-reviewed reports, where imprecise and/or incorrect identifications weaken public knowledge base. can be a daunting task phytopathologists other applied biologists that need to identify Fusarium...
The occurrence of an unusual mortality event involving California sea lions (Zalophus californianus) along the central coast in May 1998 was recently reported. potent neurotoxin domoic acid (DA), produced naturally by diatom Pseudo-nitzschia australis and transmitted to via planktivorous northern anchovies (Engraulis mordax), identified as probable causative agent. Details DA analyses for anchovy tissues lion feces are described. Domoic levels were estimated samples HPLC-UV, using same...
Sea lion mortalities in central California during May and June 1998 were traced to their ingestion of sardines anchovies that had accumulated the neurotoxin domoic acid. The detection toxin urine, feces, stomach contents several sea lions represents first proven occurrence acid transfer through food chain a marine mammal. pennate diatoms, Pseudo‐nitzschia multiseries P. australis , dominant, toxin‐producing phytoplankton constituting algal blooms near Monterey Bay, Half Moon Oceano Dunes,...
Fumonisins are mycotoxins produced by some Fusarium species and can contaminate maize or products. Ingestion of fumonisins is associated with diseases, including cancer neural tube defects, in humans animals. In fungi, genes involved the synthesis other secondary metabolites often located adjacent to each gene clusters. Such encode structural enzymes, regulatory proteins, and/or proteins that provide self-protection. The fumonisin biosynthetic cluster includes 16 genes, none which appear...
Fumonisins are a family of carcinogenic secondary metabolites produced by members the Fusarium fujikuroi species complex (FFSC) and rare strains oxysporum. In Fusarium, fumonisin biosynthetic genes (FUM) clustered, cluster is uniform in gene organization. Here, sequence analyses indicated that exists five different genomic contexts, defining types. FUM genealogies, evolutionary relationships between fusaria with types were largely incongruent inferred from primary-metabolism (PM) not...
This study was conducted to determine the species identity and mycotoxin potential of 158 Fusarium strains originally archived in South African Medical Research Council's Mycotoxigenic Fungal Collection (MRC) that were reported comprise 17 morphologically distinct classic 1984 compilation by Marasas et al., Toxigenic Species: Identity Mycotoxicology. Maximum likelihood maximum parsimony molecular phylogenetic analyses single multilocus DNA sequence data indicated represented 46...
In fungi, genes involved in biosynthesis of a secondary metabolite (SM) are often located adjacent to one another the genome and coordinately regulated. These SM biosynthetic gene clusters typically encode enzymes, or more transcription factors, transport protein. Fusaric acid is polyketide-derived produced by multiple species fungal genus Fusarium. This concern because it toxic animals and, therefore, considered mycotoxin may contribute plant pathogenesis. Preliminary descriptions fusaric...
B-cells, triggered via their surface B-cell receptor (BcR), start an apoptotic program known as activation-induced cell death (AICD), and it is widely believed that this phenomenon plays a role in the restriction focusing of immune response. Although both ceramide caspases have been proposed to be involved AICD, contribution either exact molecular events through which AICD commences are still unknown. Here we show Ramos BcR-triggered associated with early rise C16 derives from activation de...
Fumonisins are polyketide-derived mycotoxins produced by the maize pathogen Fusarium verticillioides. Previous analyses identified naturally occurring variants of fungus that deficient in fumonisin C-10 hydroxylation or do not produce any fumonisins. In current study, gene deletion and genetic complementation localized deficiency to a cytochrome P450 monooxygenase biosynthetic (FUM) cluster. Sequence analysis indicated resulted from single nucleotide insertion caused frame shift coding...
T-2 toxin is a trichothecene mycotoxin produced when Fusarium fungi infect grains, especially oats and wheat. Ingestion of contaminated grain can cause diarrhea, hemorrhaging, feed refusal in livestock. Cereal crops infected with mycotoxin-producing form glycosides, sometimes called masked mycotoxins, which are potential food safety concern because they not detectable by standard approaches may be converted back to the parent during digestion or processing. The work reported here addresses...
Fusarium head blight is a plant disease with significant agricultural and health impact which affects cereal crops such as wheat, barley, maize characterized by reduced grain yield the accumulation of trichothecene mycotoxins deoxynivalenol (DON). Studies have identified production virulence factor in graminearum linked DON resistance to ability form DON-3-O-glucoside wheat. Here, structures deoxynivalenol:UDP-glucosyltransferase (Os79) from Oryza sativa are reported complex UDP an open...
Recent studies on multiple continents indicate members of the Fusarium tricinctum species complex (FTSC) are emerging as prevalent pathogens small-grain cereals, pulses, and other economically important crops. These understudied fusaria produce structurally diverse mycotoxins, among which enniatins (ENNs) moniliformin (MON) most frequent greatest concern to food feed safety. Herein a large survey in Research Center Agricultural Service culture collections was undertaken assess diversity...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 237:209-216 (2002) - doi:10.3354/meps237209 Krill: a potential vector for domoic acid in marine food webs Sibel Bargu1,*, Christine L. Powell2, Susan Coale1, Mark Busman2, Gregory J. Doucette2, Mary W. Silver1 1Department of Ocean Sciences, University California at Santa Cruz, 1156 High Street, 95064, USA...
The veA gene positively regulates sterigmatocystin production in Aspergillus nidulans and aflatoxin parasiticus flavus. Whether homologues have a role regulating secondary metabolism other fungal genera is unknown. In this study, we examined the of homologue, FvVE1, on two mycotoxin families, fumonisins fusarins, important corn pathogen Fusarium verticillioides. We found that FvVE1 deletion completely suppressed fumonisin natural substrates, rice. Furthermore, our results revealed necessary...