A5103099713- Simulation and Modeling Applications
- Machine Learning in Materials Science
- Ergonomics and Musculoskeletal Disorders
- Manufacturing Process and Optimization
- RNA Research and Splicing
- Endoplasmic Reticulum Stress and Disease
- Industrial Technology and Control Systems
- RNA modifications and cancer
- Musculoskeletal pain and rehabilitation
- Occupational health in dentistry
- Aluminum Alloy Microstructure Properties
- RNA and protein synthesis mechanisms
- 2D Materials and Applications
- Advanced Computational Techniques and Applications
- Sports Dynamics and Biomechanics
- Image Processing Techniques and Applications
- Lipoproteins and Cardiovascular Health
- Hearing Loss and Rehabilitation
- Robotics and Automated Systems
- Melanoma and MAPK Pathways
- Image and Video Stabilization
- Advanced Thermoelectric Materials and Devices
- Domain Adaptation and Few-Shot Learning
- Video Analysis and Summarization
- Effects of Vibration on Health
Jiangsu University
2024-2025
South China University of Technology
2006-2024
University of California, Riverside
2016-2024
Third Xiangya Hospital
2023
Central South University
2023
University of Birmingham
2017
Guangdong Technology College
2008
Nonsense-mediated RNA decay (NMD) selectively degrades mutated and aberrantly processed transcripts that contain premature termination codons (PTC). Cellular NMD activity is typically assessed using exogenous PTC-containing reporters. We overcame some inherently problematic aspects of assaying endogenous targets developed a broadly applicable strategy to reliably easily monitor changes in cellular activity. Our new method was genetically validated for distinguishing regulation from...
Generative models for 2D materials have shown significant promise in accelerating the material discovery process. The stability and performance of these are strongly influenced by their underlying symmetry. However, existing generative often neglect symmetry constraints, leading to a tendency generate overly complex, low-symmetry structures. Here, we introduce symmetry-constrained diffusion model (SCDM) that integrates space group into By incorporating Wyckoff positions, ensures adherence...
Nonsense-mediated mRNA decay (NMD) degrades transcripts with premature stop codons. Given the prevalence of nonsense single nucleotide polymorphisms (SNPs) in general population, it is urgent to catalog effects clinically approved drugs on NMD activity: any interference could alter expression SNPs, inadvertently inducing adverse effects. This risk higher for patients disease-causing mutations or an illness linked dysregulated transcripts. On other hand, hundreds disorders are affected by...
Based on anecdotal and observational evidence, we hypothesized that the prevalence of cervical musculoskeletal disorder (C-MSD) would be high among plastic surgeons. A questionnaire review was undertaken to test this hypothesis. Ergonomic assessment assess causal factors C-MSD.An anonymous recording demographics, physical symptoms behavioral responses C-MSD distributed UK Plastic Surgery consultants. The postural impact wearing loupes assessed using motion capture techniques muscular...
Abstract Efficiently generating energetically stable crystal structures has long been a challenge in material design, primarily due to the immense arrangement of atoms lattice. To facilitate discovery materials, we present framework for generation synthesizable materials leveraging point cloud representation encode intricate structural information. At heart this lies introduction diffusion model as its foundational pillar. gauge efficacy our approach, employed it reconstruct input from...
Abstract Magnesium-aluminum alloy is one of the most common materials in industry, widely utilized due to its low density and excellent mechanical properties. However, investigating properties or predicting new structures through experiment inevitably involves complex processes, which cost much time money. Currently, simulations, such as functional theory (DFT) machine learning (ML) methods, are mainly employed for materials. While precise, DFT incurs significant computational costs, posing...
CRKL (CRK Like Proto-Oncogene) belongs to the Crk family and is a 39-kDa adapter protein that encodes SH2 SH3 (src homologs) domains. To identify its oncogenic role in malignant melanoma, we investigated association between mutation, prognosis, tumor mutation burden, immune cell infiltration of explored associations immunotherapy response. Our results showed abnormal expression associated with poor prognosis melanoma significantly correlated immune-activated pathways processes,...
X-inactive-specific transcript (Xist) is a long noncoding RNA (lncRNA) essential for inactivating one of the two X chromosomes in mammalian females. Random chromosome inactivation mediated by Xist expressed from inactive chromosome. We found that unspliced naïve embryonic stem (ES) cells. Upon differentiation, splicing becomes efficient across all exons independent transcription, suggesting interdependent or coordinated removal introns. In female cells with mutated polypyrimidine tract...
Plastic surgeons report neck, shoulder and back pain when wearing head-mounted magnifiers (loupes) during operations. There will be many factors contributing to such pain. In order explore these this paper developed a novel application of Multi-objective Optimization (MOO) which used postural constraints on anthropometric models determine Rapid Upper Limb Analysis (RULA) scores. For the experienced by loupes, analyses showed that adjusting height table suitable working distance loupes for...
At present, cloud robots tend to be intelligent and cooperative. Based on this, we proposed a teaching method based Imitation learning that incorporates Incremental Learning Meta Learning. We use teach robots, more concretely, propose natural visual sense by using depth camera, the robot can learn from trajectory caught camera. helps understand task split it into some subtasks which enhances level of generalization. Besides, once circumstances change update database Using method, make...
Efficiently generating energetically stable crystal structures has long been a challenge in material design, primarily due to the immense arrangement of atoms lattice. To facilitate discovery materials, we present framework for generation synthesizable materials leveraging point cloud representation encode intricate structural information. At heart this lies introduction diffusion model as its foundational pillar. gauge efficacy our approach, employed it reconstruct input from training...
Generative model for 2D materials has shown significant promise in accelerating the material discovery process. The stability and performance of these are strongly influenced by their underlying symmetry. However, existing generative models often neglect symmetry constraints, which limits both diversity quality generated structures. Here, we introduce a symmetry-constrained diffusion (SCDM) that integrates space group into By incorporating Wyckoff positions, ensures adherence to principles,...
Efficiently generating energetically stable crystal structures has long been a challenge in material design, primarily due to the immense arrangement of atoms lattice. To facilitate discovery material, we present framework for generation synthesizable materials, leveraging point cloud representation encode intricate structural information. At heart this lies introduction diffusion model as its foundational pillar. gauge efficacy our approach, employ it reconstruct input from training...
Headphones are wearable devices that directly contact the human body. Ergonomics focuses on wearing comfort associated with clamping force, which is closely related to user's tactile perception. Additionally, as auditory input terminal devices, headphones should also encompass aspect of hearing comfort. Theoretically, slight and uneven force may cause noise exposure, subsequently influencing Conversely, an overloaded while aiming improve conditions, introduce discomfort for wearer....
Sound localization is an essential ability for normal hearing listeners, aiding in the of objects and detection potential dangers, as well enabling extraction target speech information a noisy environment. However, high-frequency loss, commonly observed elderly population, may lead to decline spatial ability. The present work evaluated horizontal 60 individuals psychoacoustic experiment investigated relationship between impairment loss different frequency ranges. Results indicate that above...
Early stage or localized melanoma can be surgically resected with satisfactory outcome, whereas advanced malignant responds to treatment poorly and has a negative prognosis even after surgery, radiotherapy other comprehensive treatments. Gene therapy targeting various biological signaling pathways become an increasingly popular area in research. However, for gene success, it is important reveal the molecular mechanisms of tumorigenesis development. The present study examined effects...
In order to fulfill increasing individual and various customers demands products, characteristics of typical product design patterns are introduced their respective limitations analyzed in this paper firstly. Based on this, one new interactive innovative pattern based knowledge engineering (IPIDP-KBE) is put forward, which compared with mass customization detail. Furthermore, a system framework IPIDP-KBE as well its key technologies also presented the following section. This consists four...
On the basis of analysis representation for two-dimensional drawings, authors studied basic forms three-dimensional drawings and national standards regarding its newest criterions as well requirement, then presented a new Description engineering drawing under software circumstance features modeling, which applied all kinds methods manual introduced to implement three dimensional drawings. This method took advantage digital product definition data enriched means