A5043639661- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Mosquito-borne diseases and control
- Pharmaceutical Quality and Counterfeiting
- Leptospirosis research and findings
- Malaria Research and Control
- Parasites and Host Interactions
- Hemoglobinopathies and Related Disorders
- Drug-Induced Hepatotoxicity and Protection
- Vector-borne infectious diseases
- Reproductive Health and Contraception
- Pneumonia and Respiratory Infections
- Biosimilars and Bioanalytical Methods
- Human Rights and Development
- HIV/AIDS Research and Interventions
- Pharmacological Effects and Toxicity Studies
- HIV/AIDS drug development and treatment
- Parasitic Diseases Research and Treatment
- Pharmaceutical Practices and Patient Outcomes
- Meta-analysis and systematic reviews
- Global Health Care Issues
- Antibiotic Resistance in Bacteria
- Food Security and Health in Diverse Populations
Infectious Diseases Data Observatory
2020-2024
University of Oxford
2020-2024
Worldwide Veterinary Service
2023
Angkor Hospital for Children
2020-2023
Drugs for Neglected Diseases Initiative
2023
Mahidol Oxford Tropical Medicine Research Unit
2022
Mahidol University
2022
University of Toronto
2020
Economic & Social Sciences, Health Systems & Medical Informatics
2016-2018
Université Côte d'Azur
2016
<ns4:p>While the world is facing urgency of COVID-19 pandemic, policymakers must plan for direct response to outbreak while minimising its collateral impact. Maintaining supply chain pharmaceutical products not only paramount cover immediate medical but will be fundamental reducing disruption healthcare delivery system, which requires constant medicines, diagnostic tools and vaccines smooth functioning. In this equation, role Indian industry critical meet domestic need over 1.3 billion...
Background Antimicrobial resistance (AMR) is a major global public health threat requiring urgent action. Pan-European data on knowledge, attitudes and behaviors among the general regarding antibiotic use AMR limited. Methods A multicentric, cross-sectional survey of was conducted in capital cities 14 Member States WHO European Region. validated questionnaire from Eurobarometer used to collect access antibiotics, understanding policy responses through face-to-face exit interviews. Results...
<ns4:p><ns4:bold>Background: </ns4:bold>Since the coronavirus disease 2019 (COVID-19) outbreak was first reported in December 2019, many independent trials have been planned that aim to answer similar questions. Tools allowing researchers review studies already underway can facilitate collaboration, cooperation and harmonisation. The <ns4:ext-link xmlns:ns5="http://www.w3.org/1999/xlink" ext-link-type="uri" ns5:href="https://www.iddo.org/">Infectious Diseases Data Observatory...
Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis which can occur after successful treatment of visceral (VL) and public health problem in VL endemic areas. We conducted systematic scoping review to assess the characteristics published PKDL clinical studies, understand scope research explore feasibility value developing individual patient data (IPD) platform.
Background Reports on the occurrence and outcome of Visceral Leishmaniasis (VL) in pregnant women is rare published literature. The VL pregnancy not systematically captured cases are rarely followed-up to detect consequences infection treatment foetus. Methods A review all literature was undertaken identify infections among by searching following database: Ovid MEDLINE; Embase; Cochrane Database Systematic Reviews; Central Register Controlled Trials; World Health Organization Global Index...
Occurrences of relapse after 6-months post-treatment has been reported in recent Visceral Leishmaniasis (VL) efficacy studies. A meta-analysis was carried out to quantify the proportion relapses observed at and beyond using Infectious Diseases Data Observatory (IDDO) systematic review (SR) database. Studies IDDO SR database (1983–2021; 160 studies) were eligible for inclusion if follow-up least 6-months, clearly reported, patients with HIV coinfections excluded. Meta-analysis single...
<ns5:p><ns5:bold>Background:</ns5:bold> Many available medicines have been evaluated as potential repurposed treatments for coronavirus disease 2019 (COVID-19). We summarise the registered study landscape 32 priority pharmacological identified following consultation with external experts of COVID-19 Clinical Research Coalition.</ns5:p><ns5:p> <ns5:bold>Methods:</ns5:bold> All eligible trial registry records by systematic searches World Health Organisation International Trials Registry...
This study aims to provide a landscape of the global antiretroviral (ARV) market by analyzing transactional data on donor-funded ARV procurement between 2003 and 2015, price determinants.The were obtained from Global Price Reporting Mechanism (GPRM) managed AIDS Medicines Diagnostics Service WHO, it consists information that covers approximately 80% total adult transactions procurement.ExWorks prices procured quantities standardized according guidelines in terms yearly doses. Descriptive...
Abstract Background Plasmodium vivax remains a major challenge for malaria control and elimination due to its ability cause relapsing illness. To prevent relapses the Indian National Center Vector Borne Diseases Control (NCVBDC) recommends treatment with primaquine at dose of 0.25 mg/kg/day provided over 14 days. Shorter courses may improve adherence effectiveness. Methods This is hospital-based, randomised, controlled, open-label trial in two centres India. Patients above age 16 years,...
ABSTRACT. Surveillance for genetic markers of resistance can provide valuable information on the likely efficacy antimalarials but needs to be targeted ensure optimal use resources. We conducted a systematic search and review publications in seven databases compile marker data from studies India. The sample collection identified this was between 1994 2020, these were published 2022. In all, Plasmodium falciparum Kelch13 (PfK13), P. dihydropteroate synthase, dihydrofolate reductase (PfDHPS)...
Since the early 2000s, question of access to medicines at affordable prices for Southern populations has appeared as one major challenges international governance health. But what is stake creation market in global South, particularly countries Sub-Saharan Africa. These markets are new nature sense that they driven by organisations where firms, especially from India, occupy an increasingly important position. However, specificity these and way constituted have been little analysed. In this...
<ns4:p><ns4:bold>Introduction: </ns4:bold>Visceral leishmaniasis (VL) is a vector-borne disease caused by protozoan parasites of the genus Leishmania. The endemic in parts South Asia, East Africa, America and Mediterranean region, with an estimated 50,000 to 90,000 cases occurring annually. A living systematic review existing scientific literature proposed identify clinical drug efficacy studies against VL, conducted following Preferred Reporting Items for Systematic-Reviews Meta-Analyses...
Introduction Visceral leishmaniasis (VL) is a parasitic disease with an estimated 30 000 new cases occurring annually. There observed variation in the efficacy of current first-line therapies across different regions. Such heterogeneity could be function host, parasite and drug factors. An individual participant data meta-analysis (IPD-MA) planned to explore determinants treatment outcomes. Methods analysis The Infectious Diseases Data Observatory (IDDO) VL living systematic review (IDDO...
Abstract Background Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis which can occur after successful treatment of visceral (VL) and public health problem in VL endemic areas. We conducted systematic scoping review to assess the characteristics published PKDL clinical studies, understand scope research explore feasibility value developing individual patient data (IPD) platform. Methods A literature was identify studies by searching following databases: PubMed, Scopus, Ovid Embase,...
Introduction Visceral leishmaniasis (VL) is a parasitic disease with an estimated 30 000 new cases occurring annually. Despite anaemia being common haematological manifestation of VL, the evolution different characteristics following treatment remains poorly understood. An individual participant data meta-analysis (IPD-MA) planned to characterise dynamics in patients VL. Methods and analysis The Infectious Diseases Data Observatory (IDDO) VL platform global repository IPD from therapeutic...