A5101628043- Magnesium Alloys: Properties and Applications
- Corrosion Behavior and Inhibition
- Hydrogen Storage and Materials
- Aluminum Alloys Composites Properties
- Cardiac Fibrosis and Remodeling
- Fluorine in Organic Chemistry
- Lung Cancer Treatments and Mutations
- RNA modifications and cancer
- Glioma Diagnosis and Treatment
- Per- and polyfluoroalkyl substances research
- Inorganic Fluorides and Related Compounds
- Genetic factors in colorectal cancer
- Polysaccharides Composition and Applications
- Bone Tissue Engineering Materials
- Natural product bioactivities and synthesis
- Eicosanoids and Hypertension Pharmacology
- Proteins in Food Systems
- Neuroinflammation and Neurodegeneration Mechanisms
- Muscle metabolism and nutrition
- Advanced MRI Techniques and Applications
- Autophagy in Disease and Therapy
- Fatty Acid Research and Health
- Microencapsulation and Drying Processes
- Signaling Pathways in Disease
- Cyclopropane Reaction Mechanisms
Bengbu Medical College
2025
Nanjing Drum Tower Hospital
2024
Imperial College London
2022-2024
Zhejiang Provincial People's Hospital
2023
Hangzhou Medical College
2023
Chongqing Medical University
2017-2022
Children's Hospital of Chongqing Medical University
2022
The Affiliated Yongchuan Hospital of Chongqing Medical University
2017-2021
Fudan University
2016-2020
Huashan Hospital
2020
WE43 magnesium alloy has been considered as a promising candidate material for biodegradable coronary stents. In order to evaluate the effects of blood flow on corrosion process Mg and its alloys, behaviours cast pure extruded in Hank's solution under three different conditions, i.e. static, stirring flowing, were investigated present work. We found that exhibited much higher rate than regardless liquid flowing condition solution. Both samples lowest while promoted local with rates six times...
Abstract Hepatocellular carcinoma (HCC) stands as the fifth most prevalent malignant tumor on a global scale and presents second leading cause of cancer-related mortality. DNA damage-based radiotherapy (RT) plays pivotal role in treatment HCC. Nevertheless, radioresistance remains primary factor contributing to failure radiation therapy HCC patients. In this study, we investigated functional transketolase (TKT) repair double-strand breaks (DSBs) Our research unveiled that TKT is involved DSB...
To reduce the biocorrosion rate and enhance biocompatibility by surface modification, MgF 2 coatings were prepared on Mg–1Ca alloy using vacuum evaporation deposition method. The average thickness of coating was about 0.95 µm. results immersion test electrochemical indicated that corrosion effectively decreased after with . induced calcium phosphate alloy. After 72 h culture, MG63 cells MC3T3‐E1 well spread ‐coated alloy, while few observed uncoated samples. In summary, showed beneficial...
A simple, efficient, and mild method for defluorination functionalization of 3,3,3-trifluoro carbonyl compounds has been developed. In the present method, Cs2CO3 can easily convert α-trifluoromethyl esters, amides, ketones into β,β-S-, O- and/or N-substituted α,β-unsaturated in presence N-, O-, S-nucleophiles with moderate to excellent yields, furthermore, this transformation ester a series 2-aminophenols result benzooxazoles good yields.
Abstract This study aimed to investigate the effect and mechanism of 2α, 3α, 24‐thrihydroxyurs‐12‐en‐24‐ursolic acid (TEOA) alone or in combination with cisplatin on oral cancer. TEOA, a pentacyclic triterpenoid compound isolated from roots Actinidia eriantha , has demonstrated antitumor activity preclinical experiments. However, its role cancer remains poorly understood. Our findings revealed that low concentration TEOA did not exhibit significant cytotoxicity against squamous cell...
Cardiac fibrosis occurs in a wide range of cardiac diseases and is characterised by the transdifferentiation fibroblasts into myofibroblasts these cells produce large quantities extracellular matrix, resulting myocardial scar. The profibrotic process multi-factorial, meaning identification effective treatments has been limited. antifibrotic effect bile acid ursodeoxycholic (UDCA) established cases liver however its mechanism role less well understood.
Background Despite the growing concern about safety of gadolinium‐based contrast agents (GBCAs), they are still most commonly used. Ferumoxytol, as an off‐label alternative MRI agent, cannot be administered by a rapid bolus for dynamic susceptibility perfusion‐weighted imaging (DSC‐PWI). Purpose To assess feasibility iron sucrose (IS) agent MR angiography (MRA) and DSC‐PWI. Study Type Prospective animal model. Animal Model Thirty‐six normal rats (16 MRA, 20 biocompability tests) 36 occlusion...
Colorectal cancer (CRC) is one of the most common digestive tract tumors in humans. At present, many scholars believe that primary site tumor has a direct and profound impact on its curative effect. There are significant differences expression genes, microenvironment, prognosis between left right colon. However, there lack detailed studies whether differentially expressed genes colon significantly patients with CRC. Troponin T1 ( TNNT1 ) an important gene affects difference screening from...
In a prospective study involving 43 participants with Cushing disease, the incorporation of gallium 68 ( Ga) pentixafor PET/MRI demonstrated promising sensitivity, which was higher than contrast-enhanced MRI alone in localizing adrenocorticotropic hormone–secreting pituitary tumors.
Abstract Cardiac fibrosis occurs in a wide range of cardiac diseases and is characterised by the transdifferentiation fibroblasts (FB) into myofibroblasts (MFB). Myofibroblasts produce large quantities extracellular matrix proteins, resulting myocardial scar. The antifibrotic effect bile acid ursodeoxycholic (UDCA) established cases liver but not adult myocardium. Our hypothesis is: UDCA heart, mediated membrane receptor Takeda G protein-coupled 5 (TGR5). We constructed predictive network...
Objective To investigate the effect of olipoprotein E (ApoE) mimetic peptide on neural apoptosis and autophagy their mechanisms in mice after traumatic brain injury (TBI). Methods A total 40 health adult male C57BL/6J were randomly divided into sham-operated group, TBI+normal saline (NS) TBI+COG1410 (1 mg) group (2 (n=10). The TBI models moderate constructed by controlled cortex impact (CCI) devices later three groups performed bone window openning only. Thirty min model making,...
Introduction: Single intrauterine fetal death (sIUFD) in monochorionic diamniotic (MCDA) twin pregnancy may be associated with adverse clinical outcomes and possible metabolic changes the surviving co-twin. Metabolomic profiling has not been undertaken before these complex pregnancies. Methods: In this prospectively collected case-control study, three cross-cohort comparisons were made between sIUFD MCDA ( n = 16), uncomplicated 16, eight pairs), singleton pregnancies 8). To identify major...
Abstract Background By comparing the detection rate and type of targeted gene mutations in non-small cell lung cancer (NSCLC) between amplification refractory mutation system PCR (ARMS-PCR) next generation sequencing (NGS), characteristics application advantages are explained, providing a basis for clinicians to effectively select corresponding methods. Methods materials The cases genes were selected from First Affiliated Hospital Chongqing Medical University January 2016 October 2020. A...
Abstract Background By comparing the detection rate and type of targeted gene mutations in non-small cell lung cancer (NSCLC) between amplification refractory mutation system PCR (ARMS-PCR) next generation sequencing (NGS), characteristics application advantages are explained, providing a basis for clinicians to effectively select corresponding methods. Methods materials The cases genes were selected from First Affiliated Hospital Chongqing Medical University January 2016 October 2020. A...