A5078120676- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Pneumonia and Respiratory Infections
- Escherichia coli research studies
- Bacterial Infections and Vaccines
- Mosquito-borne diseases and control
- Asthma and respiratory diseases
- Influenza Virus Research Studies
- Social Sciences and Policies
- Sports Performance and Training
- Viral Infections and Immunology Research
- SARS-CoV-2 and COVID-19 Research
- Allergic Rhinitis and Sensitization
- Neonatal Respiratory Health Research
- Infective Endocarditis Diagnosis and Management
- Antibiotics Pharmacokinetics and Efficacy
- Viral Infections and Vectors
- Sports Analytics and Performance
- Cytomegalovirus and herpesvirus research
- Vaccine Coverage and Hesitancy
- Neonatal Health and Biochemistry
- Tracheal and airway disorders
- Herpesvirus Infections and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Congenital Diaphragmatic Hernia Studies
Hospital General de Niños Ricardo Gutierrez
2015-2025
University of Buenos Aires
2016-2025
Universidad Europea
2009-2024
Ministerio de Agricultura y Ganadería de Costa Rica
2024
Universidad del Salvador
2001-2023
Universidad Europea
2023
United Nations Economic Commission for Latin America and the Caribbean
2021
Gobierno de Chile
2021
Fundación Chile
2021
Universidad del Valle
2019
Shiga-like toxin-producing Escherichia coli have been associated with hemorrhagic colitis and the hemolytic uremic syndrome (HUS). Because Argentina has highest reported frequency of HUS in world, Argentine children were prospectively studied during seasons for evidence toxin-related diseases. On basis serology, fecal cytotoxin neutralization, stool cultures, DNA hybridization colony lysates, most had infection organisms. Children spring-summer diarrhea also commonly (32%, confidence...
Two pairs of oligonucleotide primers were designed to amplify fragments the genes for Shiga-like toxin I (SLT-I) and SLT-II in a single reaction. A 370-bp segment 283-bp amplified SLT-I SLT-II, respectively. The specificities polymerase chain reaction (PCR) amplification products confirmed by using radioactively labeled probes. SLT sequences from DNA isolated 13 previously characterized enterohemorrhagic Escherichia coli (EHEC) strains. No product was produced 20 non-EHEC As little as one...
Shiga-like toxin-producing Escherichia coli (STEC) infection causes diarrhea, which is often bloody and can result in potentially life-threatening hemolytic-uremic syndrome (HUS). Urtoxazumab, a humanized monoclonal antibody directed against the toxin 2 (Stx2) produced by STEC, has been developed as promising agent for prevention of HUS. Single randomized, intravenous, double-blind, placebo-controlled doses urtoxazumab were administered to assess its safety pharmacokinetics healthy adults...
SUMMARY Meningococcal serogroup W strains have been emerging throughout the current century with most of isolates belonging to sequence type (ST11)/electrophoretic (ET37) clonal complex (ST11/E37 CC), particularly since international outbreak following Hajj 2000. That appears triggered off that trend, contributing spread ST11/ET37 CC globally; however, local could be also responsible for increases in percentage and/or incidence rates this some countries. More recently, unexpected and rate...
Background. Streptococcus pneumoniae is a major cause of acute otitis media (AOM) in young children. More than 90 immunologically distinct pneumococcal serotypes have been identified, but limited information available regarding their relative importance AOM. Methods. We analyzed nine existing datasets comprising isolates from middle ear fluid samples collected 1994 through 2000 3232 children with AOM Finland, France, Greece, Israel, several East European countries, the US and Argentina....
Summary Backgroud Epithelial cells release cytokines and they probably contribute to chronic inflammation detected in bronchial asthma, rhinitis nasal polyposis. Objectives To investigate the effect of cultures on cytokine gene expression compare epithelial cell by both healthy nucosa (HNM) polyps (NP), modulation dexamethasone which may promote eosinophil survival. Methods Epithelials were cultured confluence, human conditioned media generated with or without dexamethasone, supernalanls...
Background and Aims: Shiga-like toxin (Stx)-producing Escherichia coli (STEC) infection is an ongoing health issue that can lead to serious complications, including hemolytic uremic syndrome (HUS) death. This study assessed demographic epidemiologic information of STEC among Argentinean children. Methods: A prospective surveillance 2435 screened children (age, 0.5–15 years) presenting with watery diarrhea and/or bloody was undertaken evaluate the clinical course infection. Results:...
Abstract Background Enterobacterales and Pseudomonas aeruginosa cause invasive infections their spread of antimicrobial resistance is great concern in the worldwide scientific community. Carbapenemases represent main mechanism can horizontally through mobile genetic elements. Clinical evidence suggests that mortality would be related to inadequate initial empirical treatment. Methods A prospective observational study was carried out three tertiary care pediatric hospitals Argentina, since...
Abstract Background Between epidemiological weeks (EW) 1 and 13 of 2024, the Region Americas reported 4,820,955 suspected dengue cases, triple count from 2023. Argentina ranked second with 379,341 a fourfold increase previous season. Our aim is to describe behavior in pediatric population during 2023 2024 compare characteristics latest two outbreaks Argentina. Methods Two cross-sectional studies were conducted children’s hospital Buenos Aires City. Clinical, epidemiological, laboratory,...
Abstract Background PCV13 was included in Argentina NIP 2012 with 2 +1 schedule at 2, 4 and 12-15 mo of age. After 11 yrs program, from May´23-Mar´24 we carried out a multicentric prospective study to evaluate impact pneumococcal disease, S.pneumoniae (Spn) serotype(S) distribution AST. Methods Study Population: 1 10 yr old hospitalized children by IPD and/or CAP 8 pediatric centers; f-up 6 mo. Clinical record completed for subjects who met inclusion criteria after written Inform Consent...
En el planeta tierra existen sustancias químicas que resultan de procesos químicos intencionados, artificiales o sintéticos. Aminorar sus efectos sobre los ecosistemas y la salud humana constituye un reto importante para sociedad actual, especialmente en región latinoamericana. El objetivo este estudio fue revisar importancia promover educación las su impacto ambiente humana. La investigación está basada una revisión sistemática bibliografía científica asociada a manejo Latinoamérica, entre...
El presente artículo busca describir de manera sistematizada las experiencias estudiantes la carrera comunicación que implementaron en 2023 un proyecto sobre educación socioemocional para niños y niñas una comunidad escolar Suchitlán, Colima. Se trata del resultado trabajo incluyó diagnósticoparticipativo, campaña recolección libros, así como el diseño implementación seis talleres enfocados procesos dentro actividades centro escolar, parte aplicación conocimientos recibidos materia...
Summary Eosinophilic infiltration of the respiratory mucosa is considered an inflammatory hallmark allergic rhinitis, bronchial asthma and nasal polyposis. However, mechanisms involved in this have not yet been totally elucidated. The objective study was to investigate compare influence epithelial cell secretions from both polyps (NP) normal (NM) on vitro eosinophil survival. Epithelial cells were identified by microscopy; immunohislochemisiry. cultured confluence, human conditioned media...
Supernatants from epithelial cell cultures enhance eosinophil survival in vitro, this effect being abrogated by previous incubation of eosinophils with glucocorticosteroids. This property has resulted the development an vitro test to compare potency these drugs. A comparative study was performed dexamethasone, methylprednisolone, deflazacort, and budesonide.Human conditioned media (HECM) generated cultured cells obtained healthy nasal mucosa polyps. Eosinophils isolated peripheral blood were...
Hemolytic uremic syndrome (HUS) is thought to be a vascular endothelial injury disease. The mechanism of unknown although verocytotoxins (Shiga-like toxins (SLTs)) are known associated with it. Recent evidence suggests that in vitro treatment some cells tumor necrosis factor alpha (TNF-alpha) dramatically increases their susceptibility SLTs. We studied 25 children HUS, 63 SLT-positive bloody diarrhea, 62 diarrhea not SLTs and 39 admitted for elective surgery, included as an age-...
After a 2014 outbreak of severe respiratory illness caused by enterovirus D68 in the United States, sporadic cases acute flaccid myelitis have been reported worldwide. We describe cluster Argentina 2016, adding data to evidence association between and this polio-like illness.
El objetivo del presente estudio fue mejorar la comprensión acerca uso ataque colocador en competiciones de alto nivel. Se analizaron todos los partidos Juegos Olímpicos Tokio 2020, registrando un total 218 acciones colocador. Para el análisis datos se empleó Chi-cuadrado Pearson y curvas ROC. obtuvo más puntos creó menos errores cuando realizó después excelente envío al (X2 = 15.53; p .004). En categoría femenina, utilizado con mayor frecuencia que masculina una calidad (X2=14.35; p=.001),...
Morbidity and mortality rates for pertussis in infants are high because disease often occurs before the onset of routine immunization or those who do not complete a primary series. Pertussis is recommended during pregnancy to achieve antibody levels sufficient protect young infants. To our knowledge, no previous reports maternal results Latin America exist literature.This study compared newborns from mothers received did receive tetanus-diphtheria-acellular vaccination (TdapV) pregnancy....
Topical anti-inflammatory drugs decrease eosinophil infiltration. This action may be due to an effect on the release of epithelial cell products responsible for promoting survival. We investigated fluticasone propionate, budesonide, beclomethasone dipropionate and nedocromil sodium granulocyte/macrophage colony-stimulating factor (GM-CSF) survival induced by secretions from cultured nasal cells. Human cell-conditioned media (HECM) were generated cells obtained healthy subjects undergoing...