- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Pain Management and Treatment
- Vestibular and auditory disorders
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Neural and Behavioral Psychology Studies
- Neurological disorders and treatments
- Laser Applications in Dentistry and Medicine
- Vagus Nerve Stimulation Research
- Neurobiology of Language and Bilingualism
- Migraine and Headache Studies
- Ultrasound and Hyperthermia Applications
- Pain Mechanisms and Treatments
- Tactile and Sensory Interactions
- Intraoperative Neuromonitoring and Anesthetic Effects
- Photoacoustic and Ultrasonic Imaging
- Advanced Neuroimaging Techniques and Applications
- Spatial Neglect and Hemispheric Dysfunction
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Hearing, Cochlea, Tinnitus, Genetics
- Attention Deficit Hyperactivity Disorder
Soterix Medical (United States)
2012-2024
City College of New York
2013-2022
City University of New York
2012-2022
City College
2015-2022
Inserm
2019
Sorbonne Université
2019
Institut du Cerveau
2019
Centre National de la Recherche Scientifique
2019
Universitat Oberta de Catalunya
2019
Center for Discovery
2018
Transcranial Direct Current Stimulation (tDCS) is a non-invasive, versatile, and safe neuromodulation technology under investigation for the treatment of neuropsychiatric disorders, adjunct to rehabilitation, cognitive enhancement in healthy adults. Despite promising results, there variability responsiveness. One potential source intensity current delivered brain which function both operator controlled tDCS dose (electrode montage total applied current) subject specific anatomy. We are...
Recent studies show that acute neuromodulation of the prefrontal cortex with transcranial direct current stimulation (tDCS) can decrease food craving, attentional bias to food, and actual intake. These data suggest potential clinical applications for tDCS in field obesity. However, optimal parameters obese individuals are uncertain. One fundamental concern is whether a thick, low-conductivity layer subcutaneous fat around head affect density distribution require dose adjustments during...
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that applies low amplitude via electrodes placed on the scalp. Rather than directly eliciting neuronal response, tDCS believed to modulate excitability-enhancing or suppressing activity in regions of brain depending polarity stimulation. The specificity any therapeutic application derives part from how electrode configuration determines are stimulated. Conventional uses two relatively large pads (>25...
BackgroundMeasurements and models of current flow in the brain during transcranial Direct Current Stimulation (tDCS) indicate stimulation regions in-between electrodes. Moreover, folded cortex results local fluctuations intensity direction, animal studies suggest direction relative to cortical columns determines response tDCS.MethodsHere we test this idea by using Transcranial Magnetic Motor Evoked Potentials (TMS-MEP) measure changes corticospinal excitability following tDCS applied with...
Although transcranial direct current stimulation (tDCS) studies promise to modulate cortical regions associated with pain, the electric produced usually spreads beyond area of electrodes’ placement. Using a forward-model analysis, this study compared neuroanatomic location and strength predicted peaks, at subcortical levels, induced by conventional High-Definition-tDCS (HD-tDCS) montages developed for migraine other chronic pain disorders. The electrodes were positioned in accordance 10-20...
Understanding which cellular compartments are influenced during neuromodulation underpins any rational effort to explain and optimize outcomes. Axon terminals have long been speculated be sensitive polarization, but experimentally informed models for CNS stimulation lacking. We conducted simultaneous intracellular recording from the neuron soma axon terminal (blebs) extracellular with weak sustained (DC) uniform electric fields in mouse cortical slices. Use of direct current (DCS) allowed...
Objective Transcranial direct current stimulation (tDCS) has been shown to improve pain symptoms in fibromyalgia (FM), a central syndrome whose underlying mechanisms are not well understood. This study was undertaken explore the neurochemical action of tDCS brain patients with FM, using proton magnetic resonance spectroscopy ( 1 H‐MRS). Methods Twelve FM underwent sham over left motor cortex (anode placement) and contralateral supraorbital (cathode for 5 consecutive days, followed by 7‐day...
Tinnitus is the perception of a phantom sound. The aim this study was to compare current intensity (center anode 1 mA and 2 mA), duration (10 minutes 20 minutes), location (left temporoparietal area [LTA] dorsolateral prefrontal cortex [DLPFC]) using 4 × high-definition transcranial direct stimulation (HD-tDCS) for tinnitus reduction.Twenty-seven participants with chronic (>2 years) mean age 53.5 years underwent sessions HD-tDCS LTA DLPFC in randomized order week gap between site...
Noninvasive brain stimulation in primary progressive aphasia (PPA) is a promising approach. Yet, applied to single cases or insufficiently controlled small-cohort studies, it has not clarified its therapeutic value. We here address the effectiveness of transcranial direct current (tDCS) on semantic PPA variant (sv-PPA), applying rigorous study design large, homogeneous sv-PPA cohort.Using double-blind, sham-controlled counterbalanced cross-over design, we three tDCS conditions targeting...
Abstract Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation technique that applies mA currents at the scalp to modulate cortical excitability. Here, we present a novel magnetic resonance imaging (MRI) technique, which detects fields induced by tDCS currents. This based on Ampere’s law and exploits linear relationship between fields. Following validation phantom with known path of electric field, proposed MRI was applied human limb (to demonstrate...
Motor cortex (MCX) motor representation reorganization occurs after injury, learning, and different long-term stimulation paradigms. The neuromodulatory approach of transspinal direct current (tsDCS) has been used to promote evoked cortical responses. In the present study, we cathodal tsDCS (c-tsDCS) rat cervical cord determine if spinal activation can modify MCX forelimb map. We a finite-element method model based on coregistered high-resolution MRI microcomputed tomography imaging data...
Objective. There is longstanding interest in using EEG measurements to inform transcranial Electrical Stimulation (tES) but adoption lacking because users need a simple and adaptable recipe. The conventional approach use anatomical head-models for both source localization (the inverse problem) current flow modeling tES forward model), this computationally demanding, requires an MRI, strict assumptions about the target brain regions. We evaluate techniques whereby dose derived from without...