A5061047921- Phytochemicals and Medicinal Plants
- Advanced Drug Delivery Systems
- Phytochemistry and Biological Activities
- Natural Antidiabetic Agents Studies
- Ethnobotanical and Medicinal Plants Studies
- Drug-Induced Hepatotoxicity and Protection
- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Drug Solubulity and Delivery Systems
- Medicinal Plants and Neuroprotection
- Phytochemistry and Bioactivity Studies
- Ocular Surface and Contact Lens
- Liver Disease Diagnosis and Treatment
- Toxin Mechanisms and Immunotoxins
- Ziziphus Jujuba Studies and Applications
- Aluminum toxicity and tolerance in plants and animals
- Endoplasmic Reticulum Stress and Disease
- Bioactive natural compounds
- IL-33, ST2, and ILC Pathways
- Alzheimer's disease research and treatments
- Pharmaceutical studies and practices
- Phytochemical compounds biological activities
- Complementary and Alternative Medicine Studies
- Phytochemicals and Antioxidant Activities
- Diverse Scientific Research Studies
Siksha O Anusandhan University
2016-2025
Pharmac
2024
University of California, Los Angeles
2024
Central Council for Research in Ayurvedic Science
2021-2023
Government of India
2021-2023
Ministry of AYUSH
2021-2023
Indian Institute of Chemical Biology
2019-2022
Council of Scientific and Industrial Research
2022
University of Saskatchewan
2019
Institute of Minerals and Materials Technology
1980
The medicinal plants are widely used by the traditional practitioners for curing various diseases in their day to practice. In system of medicine, different parts (leaves, stem, flower, root, seeds and even whole plant) Ocimum sanctum Linn. have been recommended treatment bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases, insect bites so on. O. L. has also suggested possess anti-fertility, anticancer, antidiabetic, antifungal, antimicrobial, cardioprotective,...
Urinary tract infection (UTI) has become a more grievous problem today, due to multidrug resistance of infecting Gram-positive (GP) and Gram-negative (GN) bacteria, sometimes even with multiple infections. This study examines effectivity 9 tropical flowering plants (Anogeissus acuminata, Azadirachta indica, Bauhinia variegata, Boerhaavia diffusa, Punica granatum, Soymida febrifuga, Terminalia chebula, Tinospora cordifolia Tribulus terrestris) for possible use as source antimicrobials...
To investigate antioxidant potential of methanol extract Alpinia nigra leaves. The study was done by using various In vitro methods such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS), nitric oxide and hydrogen peroxide radical scavenging assays. Phytochemical constituents, total phenolic content flavonoid the at different concentrations (10-500 μg/mL) were determined. leaves showed high free activity evidenced low IC50 values in DPPH...
Background: Ardisia solanacea (Poir.) Roxb, a member of the Myrsinaceae family, is regarded as significant medicinal plant according to traditional claims. This herb documented address various conditions, including mental disorder, dysmenorrhea, diarrhoea, gout, RA, vertigo, and skin sores. Aim: The study investigates inhibitory effect A. (family: Myrsinaceae), an indigenous against pro inflammatory cytokines such Interleukin-6 (IL-6) Tumour Necrosis Factor-alpha (TNF-α) using in vivo, ex...
Timed feeding drives adipose browning, although the integrative mechanisms for same remain unclear. Here, we show that twice-a-night (TAN) generates biphasic oscillations of circulating insulin and leptin, representing their entrainment by timed feeding. Insulin leptin surges lead to marked cellular, functional, metabolic remodeling subcutaneous white tissue (sWAT), resulting in increased energy expenditure. Single-cell RNA-sequencing (scRNA-seq) analyses flow cytometry demonstrate a role...
Lipophagy is a ubiquitous mechanism for degradation of lipid droplets (LDs) in lysosomes. Autophagy receptors selectively target organelles lysosomal degradation. The selective receptor lipophagy remains elusive. Using mouse liver phosphoproteomics and human transcriptomics, we identify vacuolar-protein-sorting-associated protein 4A (VPS4A), member large family AAA+ ATPases, as lipophagy. We show that phosphorylation VPS4A on Ser95,97 its localization to LDs response fasting drives...
The present study was undertaken for characterization of the steady state and non corneal permeation kinetics diclofenac potassium (DCP) using statistical moment theory.
Antibacterial activity of Ascidian phallusia arabica against human clinical isolatesSelva Prabhu A, G. Ananthan, S. Mohamed Hussain, T. Balasubramanian
Incidence of hepatotoxicity following acute drug-induced proteasomal inhibition and development chronic proteasome dysfunction in obesity insulin resistance underscores the crucial importance hepatic protein homeostasis albeit with an elusive molecular basis therapeutic opportunities. Apart from lipotoxicity endoplasmic reticulum (ER) stress, herein we report that hepatocytes are highly susceptible to proteasome-associated metabolic stress attune altered redox homeostasis. Bortezomib-induced...
Nonalcoholic fatty liver disease (NAFLD) is an independent predictor of systemic insulin resistance and type 2 diabetes mellitus (T2DM). However, converse correlates between excess fat content β-cell function remain equivocal. Specifically, how the accumulation consequent to enhanced de novo lipogenesis (DNL) leads pancreatic failure eventually T2DM elusive. Here, we have identified that low-molecular-weight calcium-binding protein S100A6, or calcyclin, inhibits glucose-stimulated secretion...
<title>Abstract</title> <italic>Tecoma stans</italic> (L.) Juss.exKunth (Bignoniaceae) is mainly found in tropical and subtropical regions of Africa Asia. The leaves, flowers, roots, bark are used to treat various aliments includes, skin infections, kidney problems, intestinal disorders, jaundice, toothaches, joint pain repair cracked bones, antidotes for snake, scorpion, rat bites. aim the study assess anti-arthritic properties <italic>T. stans</italic>leaf using Complete Freund's adjuvant...
Every moment and every event, plant plays a vital role of man's life. The way the existence plants is great offering not only their own nutritive value but also cosmic energies which bring us universal light for Tinospora cordifolia (Guduchi-the one who protects) such plant, familiar its tramondous modern medicinal properties. Guduchi considered to be amrit having Mernispermaccae family, tropical climbing herb. term amritavalli in Sanskrit meaning creeper with amrit, being source information...
Unfolding followed by fibrillation of insulin even in the presence various excipients grappled with restricted clinical application. Thus, there is an unmet need for better thermostable, nontoxic molecules to preserve bioactive under varying physiochemical perturbations. In search cross-amyloid inhibitors, prion-derived tetrapeptide library screening reveals a consensus V(X)YR motif potential inhibition fibrillation. A VYYR, isosequential β2-strand prion, effectively suppresses heat- and...
Abstract: Introduction: Ayurveda, the science of life, has a strong heritage in India and is being practised for last several thousand years treating various ailments. Asava arista are considered as unique dosage forms Ayurveda due to their indefinite shelf life. The self generated alcohol these preparations potentiates products pharmaceutically therapeutically. Objectives: These asava popular since Samhita period better absorption, quicker action, longer life easy palatability. Methodology:...
Herbal Cosmetics have growing demand on the earth market and is a precious gift of nature. formulations continuously attracted gigantic concentration grounds that their good endeavor comparatively lesser or nil side effect with synthetic medications. Herbs spices been used in retaining embellishing human magnificence because time immemorial. Hair loss problem great significance to both men & women. The essential issues associated hair are fading, dandruff falling hair. Alopecia medical term...
Ocular drug delivery in hydrogel forming film form has several benefits over conventional dosage forms. An ophthalmic anti-inflammation study was undertaken using topically applied aspirin a formulation. A hydroxypropyl methylcellulose (HPMC) matrix formulation prepared by the solvent casting and evaporation technique taking triethanolamine (TEA) as plasticizer. Ex vivo corneal permeation well anti-inflammatory potential of studied on carrageenan induced rabbit eye model. Moisture uptake...