A5055941149- Per- and polyfluoroalkyl substances research
- Toxic Organic Pollutants Impact
- Medicinal Plants and Bioactive Compounds
- MicroRNA in disease regulation
- Effects and risks of endocrine disrupting chemicals
- Reproductive Biology and Fertility
- Cancer, Hypoxia, and Metabolism
- Ovarian function and disorders
- Fungal Biology and Applications
- Assisted Reproductive Technology and Twin Pregnancy
- Energy and Environment Impacts
- Nitric Oxide and Endothelin Effects
- Herbal Medicine Research Studies
- Circular RNAs in diseases
- Endometriosis Research and Treatment
- Pharmacological Effects of Natural Compounds
- Angiogenesis and VEGF in Cancer
- Reproductive System and Pregnancy
- Glioma Diagnosis and Treatment
- Optical Coherence Tomography Applications
- Adipose Tissue and Metabolism
- Orbital Angular Momentum in Optics
- BRCA gene mutations in cancer
- Thyroid Cancer Diagnosis and Treatment
- Cancer Cells and Metastasis
Shantou University
2025
Shantou University Medical College
2025
Karolinska University Hospital
2024
Soochow University
2018-2024
First Affiliated Hospital of Soochow University
2023-2024
Qingdao University
2021-2023
Nanfang Hospital
2011-2021
Southern Medical University
2011-2021
National Cheng Kung University
2013-2018
study question: Does NEDD8-mediated neddylation regulate human endometrial stromal proliferation and decidualization?summary answer: Neddylation inhibition by a selective NEDD8-activating enzyme inhibitor, MLN4924, significantly impairs cell (HESC) decidualization facilitates senescence, via p21 accumulation.what is known already: regulates tissue remodeling during embryogenesis tumorigenesis, while stroma undergoes sequential proliferation, differentiation, as well dynamic each menstrual...
Objective: Vascular endothelial growth factor (VEGF), apart from its predominant roles in angiogenesis, can enhance cancer cellproliferation, but mechanisms remain elusive. The purpose of the present study was therefore to identify how VEGF regulatescancer cell proliferation. Methods: effects on proliferation were investigated with receptor 2 inhibitor, Ki8751, and breastcancer lines, MCF-7 MDA-MB-231, using flow cytometry, mass spectrometry, immunoblotting, confocal microscopy.Data analyzed...
Ganoderma mushrooms, used in traditional Chinese medicine to promote health and longevity, have become widely accepted as herbal supplements. lucidum (GL), a commonly seen ganoderma species, is commercially cultivated under controlled conditions for more consistent chemical composition. The medicinal properties of GL are attributable its antioxidant anti‐inflammatory activities. We intended assess the effect atherosclerosis, an arterial condition associated with chronic oxidative stress...
Hexafluoropropylene oxide tetramer acid (HFPO-TeA) is an emerging environmental contaminant, with presence but limited toxicological information. To investigate its potential developmental toxicities, various doses of HFPO-TeA exposure were achieved in chicken embryos via air cell injection, and the exposed incubated until hatch. Within 24 h hatch, hatchling chickens assessed electrocardiography histopathology for evaluation. For mechanistic investigation, ovo silencing PPARα was lentivirus...
Ganoderma mushrooms ( Lingzhi in Chinese) have well‐documented health benefits. tsugae G. ), one of the ganoderma species, has been commercially cultivated as a dietary supplement. Because high antioxidant activity and because oxidative stress is often associated with cardiac injury, we hypothesized that protects against injury by alleviating stress. We tested hypothesis using work‐overload‐induced myocardial model created challenging mice isoproterenol (ISO). Remarkably, oral protected from...
Abstract Background The utilization of liposomes in drug delivery has garnered significant attention due to their efficient loading capacity and excellent biocompatibility, rendering them a promising platform for tumor therapy. However, the average size ~ 100 nm leads being susceptible hepatic renal metabolism excretion outside body leading poor efficiency with total rate less than 0.7%, resulting unfavorable treatment outcomes. Results We have developed novel liposome equipped surface...
Abstract Background Glioblastoma is an aggressive brain tumor linked to significant angiogenesis and poor prognosis. Anti-angiogenic therapies with vascular endothelial growth factor receptor 2 (VEGFR2) inhibition have been investigated as alternative glioblastoma treatment. However, little known about the effect of VEGFR2 blockade on cells per se. Methods expression data in glioma patients were retrieved from public database TCGA. intervention was implemented by using its selective...
Background: Increasing evidence proves that long non-coding RNAs (lncRNAs) play a key role in the occurrence and development of colorectal cancer. However, function molecular mechanism LINC01836 CRC are still unknown. Methods: The differentially expressed lncRNAs cancer were obtained from RNA sequencing data. effects on cells tested vitro experiments. action was investigated through western blot, immunoprecipitation assay luciferase reporter assay. Moreover, xenograft mouse model conducted...
We derive theoretically and verify experimentally a concise general expression for the normalized intensity correlations (IC) of partially coherent light in weak atmospheric turbulence fast detector measurement regime. The derived relation reveals that medium acts, general, as an additional noise source enhancing IC beams. maximum beam is, enhanced, causing fields to exhibit super-Gaussian statistics. On other hand, indicates turbulence-induced is negligible sufficiently low coherence light,...
More than 90% of thyroid cancer belongs to the papillary and follicular carcinomas based on pathological subtypes. Papillary carcinoma are generally associated with a good prognosis. In contrast, other subtypes such as poorly-differentiated anaplastic (PDTC ATC) have poor clinical outcome short life expectancy. To identify genetic variations biomarkers that may potentially distinguish aggressive form cancer, we performed retrospective analysis formalin-fixed paraffin-embedded tumor samples...