A5018159025- Multiple Sclerosis Research Studies
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Functional Brain Connectivity Studies
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- Dementia and Cognitive Impairment Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cognitive Functions and Memory
- Neurogenesis and neuroplasticity mechanisms
- Olfactory and Sensory Function Studies
- Stroke Rehabilitation and Recovery
- Neurobiology of Language and Bilingualism
- Neuroinflammation and Neurodegeneration Mechanisms
- Memory and Neural Mechanisms
- EEG and Brain-Computer Interfaces
- Memory Processes and Influences
- Trauma and Emergency Care Studies
- Autoimmune and Inflammatory Disorders Research
- Family and Disability Support Research
- Advanced Neuroimaging Techniques and Applications
- Spinal Cord Injury Research
- Peripheral Neuropathies and Disorders
- Cerebral Palsy and Movement Disorders
- COVID-19 and Mental Health
Kessler Foundation
2016-2025
Rutgers New Jersey Medical School
2016-2025
Rutgers, The State University of New Jersey
2016-2025
Kessler Institute for Rehabilitation
2002-2023
Baylor Medical Center at Garland
2023
Rehabilitation Hospital of Indiana
2023
Indiana University
2023
Moss Rehabilitation Hospital
2023
Bureau van Dijk (Belgium)
2022
Silva
2022
Objective: To examine whether processing speed or working memory is the primary information deficit in persons with MS. Design: Case-control study. Setting: Hospital-based specialty clinic. Participants: 215 adults clinically definite Main Outcome Measure: Mean demographically corrected T-scores, prevalence rates of impairment and relative risk impaired Processing Speed Working Memory Index Scores from WAIS–WMS III. Results: Deficits were much more common than all comparisons. This was...
The need for more robust outcomes in multiple sclerosis (MS) clinical trials has been a main priority of the field decades. Dissatisfaction with existing measures led to several consensus meetings and initiatives over past few decades hopes defining gaining acceptance that are valid, reliable, sensitive change progression, most importantly, relevant those living MS. Multiple Sclerosis Outcome Assessments Consortium (MSOAC) was formed this purpose.The objective paper is describe results MSOAC...
To examine the efficacy of modified Story Memory Technique (mSMT), a 10-session behavioral intervention teaching context and imagery to facilitate learning, improve learning memory abilities in persons with multiple sclerosis (MS).This double-blind, placebo-controlled, randomized clinical trial included 86 participants clinically definite MS, 41 treatment group 45 placebo control group. Participants completed baseline neuropsychological assessment, including questionnaires assessing everyday...
The cognitive reserve hypothesis helps to explain the incomplete relationship between brain disease and status in people with neurologic diseases, including Alzheimer's; multiple sclerosis. Lifetime intellectual enrichment (estimated education or vocabulary knowledge) lessens negative impact of on cognition, such that greater are able withstand more severe neuropathology before suffering impairment dementia. current research is first investigate directly an index cerebral activity (the blood...
Abstract The List Sorting Working Memory Test was designed to assess working memory (WM) as part of the NIH Toolbox Cognition Battery. is a sequencing task requiring children and adults sort sequence stimuli that are presented visually auditorily. Validation data for 268 participants ages 20 85 years. A subset ( N =89) retested 7 21 days later. As expected, had moderately high correlations with other measures executive functioning (convergent validity) but low correlation test receptive...
To use a patient-centered approach or participatory action research design combined with advanced psychometrics to develop comprehensive patient-reported outcomes (PRO) measurement system specifically for individuals traumatic brain injury (TBI). This TBI Quality-of-Life (TBI-QOL) expands the work of other large PRO initiatives, that is, Patient-Reported Outcomes Measurement Information System and Neurology initiative.Five Model Systems centers across United States.Adults TBI.Classical...
The present study investigated the neural correlates of cognitive fatigue in Multiple Sclerosis (MS), looking specifically at relationship between self-reported and objective measures fatigue. In Experiment 1, functional magnetic resonance imaging (fMRI) was used to examine where brain BOLD activity covaried with "state" fatigue, assessed during performance a task designed induce while scanner. 2, diffusion tensor (DTI) white matter damage correlated increased "trait" individuals MS, by...
Cognitive reserve theory helps to explain the neuropsychological expression of neurologic disease (e.g., Alzheimer's disease; Stern, 2006 Y. 2006. and Alzheimer disease. Disease & Associated Disorders, 20(3, Suppl. 2): S69–S74. [Crossref], [PubMed], [Web Science ®] , [Google Scholar]). Multiple sclerosis (MS) is a characterized by information processing inefficiency verbal learning memory deficits. The current study first investigate whether higher cognitive moderates relationship between MS...
Multiple sclerosis leads to prominent hippocampal atrophy, which is linked memory deficits. Indeed, 50% of multiple patients suffer impairment, with negative consequences for quality life. There are currently no effective treatments either pharmacological or behavioral. Aerobic exercise improves and promotes neurogenesis in nonhuman animals. Here, we investigate the benefits aerobic memory-impaired patients. Pilot data were collected from two ambulatory, participants randomized non-aerobic...
<b><i>Objective:</i></b> To assess naming and recognition of faces familiar famous people in patients with epilepsy before after anterior temporal lobectomy (ATL). <b><i>Methods:</i></b> Color photographs were presented for description to 63 lobe (TLE) either or ATL 10 healthy age- education-matched controls. <b><i>Results:</i></b> Spontaneous photographed was impaired all patient groups, but most abnormal who had undergone left ATL. When allowed demonstrate knowledge the through verbal...
This randomized clinincal trial utilized established techniques to improve new learning and memory performance in multiple sclerosis (MS) participants with impairment. Participants were 29 individuals clinincally definite MS documented deficits, randomly assigned the experimental or control group. The group underwent eight sessions of Story Memory Technique (SMT), while participated exercises. Neuropsychological assessment was conducted at baseline, immediately following treatment 5 weeks...
Working memory deficits are common in Multiple Sclerosis (MS) and have been identified behaviorally numerous studies. Despite recent advance functional magnetic resonance imaging (fMRI), few published studies examined cerebral activations associated with working dysfunction MS. The present study examines brain activation patterns during performance of a task individuals clinically definite MS, compared to healthy controls (HC). fMRI was performed using 1.5 Tesla GE scanner modified Paced...
Abstract According to the cognitive reserve hypothesis, neuropsychological expression of brain disease is attenuated among persons with higher education or premorbid intelligence. The current research examined in multiple sclerosis (MS) by investigating whether negative effect atrophy on information processing (IP) efficiency moderated Thirty-eight clinically definite MS completed a vocabulary-based estimate intelligence (Wechsler Vocabulary) and composite measure IP (Symbol Digit Modalities...
Purpose. This research quantified clinical measurements and functional neural changes associated with vision therapy in subjects convergence insufficiency (CI). Methods. Convergence divergence 4° step responses were compared between 13 control adult normal binocular four CI subjects. All participated 18 h of therapy. Clinical parameters throughout the included: nearpoint convergence, recovery point positive fusional vergence at near, near dissociated phoria, eye movements that using peak...