- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Glioma Diagnosis and Treatment
- Epilepsy research and treatment
- Neuroscience and Neuropharmacology Research
- Meningioma and schwannoma management
- Acupuncture Treatment Research Studies
- Multiple Sclerosis Research Studies
- Vagus Nerve Stimulation Research
- Child and Adolescent Psychosocial and Emotional Development
- MRI in cancer diagnosis
- Neonatal and fetal brain pathology
- Health, Environment, Cognitive Aging
- Cognitive Abilities and Testing
- Bone Tumor Diagnosis and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological disorders and treatments
- Medical Imaging Techniques and Applications
- Retinal Imaging and Analysis
- Neurogenesis and neuroplasticity mechanisms
- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Birth, Development, and Health
- Stroke Rehabilitation and Recovery
The Ohio State University
2011-2024
The Ohio State University Wexner Medical Center
2014-2019
Indiana University School of Medicine
2004-2010
Indiana University
2005-2010
Indiana University – Purdue University Indianapolis
2004-2010
University School
2005-2009
University Hospital, Newark
2000-2005
Rutgers New Jersey Medical School
1997-2004
Rutgers, The State University of New Jersey
1996-2003
University of Pennsylvania
1999
<h3>SUMMARY:</h3> MR perfusion imaging is becoming an increasingly common means of evaluating a variety cerebral pathologies, including tumors and ischemia. In particular, there has been great interest in the use for both assessing brain tumor grade monitoring recurrence previously treated patients. Of various techniques devised imaging, dynamic susceptibility contrast method employed most widely among clinical practitioners. However, when implementing DSC contemporary radiology practice,...
Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies may obscure or distort lifespan trajectories of morphometry. In response, we capitalized resources Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to examine age-related inferred from cross-sectional measures ventricles, basal ganglia...
Object. The purpose of this study was to evaluate the efficacy noninvasive preoperative functional imaging data used in an interactive fashion operating room. authors describe a method registering magnetic resonance (fMR) localization sensorimotor cortex with frameless stereotactic surgical navigation device. Methods. day before surgery, patients underwent blood oxygen level—dependent fMR while performing finger-tapping motor paradigm. Immediately afterward anatomical MR image acquired. Raw...
Working memory deficits are common in Multiple Sclerosis (MS) and have been identified behaviorally numerous studies. Despite recent advance functional magnetic resonance imaging (fMRI), few published studies examined cerebral activations associated with working dysfunction MS. The present study examines brain activation patterns during performance of a task individuals clinically definite MS, compared to healthy controls (HC). fMRI was performed using 1.5 Tesla GE scanner modified Paced...
Prior research has indicated an association between exposure to violent media and aggressive thoughts, feelings, behavior, potentially as a result of effects on inhibitory mechanisms. However, the role violence in video games modulating subsequent neural activity related cognitive inhibition received little attention. To examine short-term playing game, 45 adolescents were randomly assigned play either or nonviolent game for 30 minutes immediately prior functional magnetic resonance imaging...
We present an empirically benchmarked framework for sex-specific normative modeling of brain morphometry that can inform about the biological and behavioral significance deviations from typical age-related neuroanatomical changes support future study designs. This was developed using regional morphometric data 37,407 healthy individuals (53% female; aged 3-90 years) following a comparative evaluation eight algorithms multiple covariate combinations pertaining to image acquisition quality,...
Abstract Structural neuroimaging data have been used to compute an estimate of the biological age brain (brain‐age) which has associated with other biologically and behaviorally meaningful measures development aging. The ongoing research interest in brain‐age highlighted need for robust publicly available models pre‐trained on from large samples healthy individuals. To address this we previously released a developmental model. Here expand work develop, empirically validate, disseminate model...
The present study examined patterns of cerebral activation during a working memory (WM) rehearsal task in individuals diagnosed with multiple sclerosis (MS) and healthy adults. BOLD functional magnetic resonance imaging (fMRI) was performed using 1.5 T GE scanner to assess WM adapted from the Sternberg paradigm (Sternberg, 1969). Participants included 8 MS, 5 controls (HCs) matched for age education. Task difficulty manipulated by increasing length time that strings letters were be...
BOLD fMRI was used to study acupuncture-induced activation (increase in the signal from undetectable) of periaqueductal gray (PAG) and two somatosensory cortical areas seven healthy human subjects. Mechanical stimulation (push-pull) given LI4 (Hoku) acupoint or a non-acupoint. The paradigm consisted 5 runs, each consisting four 30 s On/30 OFF periods over min. scan for ON period analyzed individually. PAG showed different activity patterns. episodic reliably demonstrated after 20–25 min...
To identify the cerebral activated regions associated with vagus nerve stimulation in epilepsy patients.Blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) was employed to detect areas of brain by five patients documented complex partial seizures.Functional MRI done on a GE 1.5T Echospeed horizon scanner. Before each patient entered scanner, vagal stimulator set specific ON-OFF paradigm so that data could be analysed using box-car type design. The brains were...
Object. The authors describe a subgroup of patients with shunt-proven normal-pressure hydrocephalus (NPH) who presented focal fissural and sulcal dilation on imaging studies. specific radiological features methods differentiating this condition from cortical atrophy are delineated. Methods. Normal-pressure has been described as the ventricles that is out proportion to sulci. Sulcal taken evidence even used criterion exclude undergoing shunting procedure. five cases NPH fissures In three...
Summary: Purpose: To explore relationships between MRI abnormalities of the brain and neuropsychological functioning in children who were evaluated following their first recognized seizure. Methods: Subjects aged 6 to 14 years with a seizure within past 3 months participated larger prospective study child adaptation. The 249 testing neuroimaging studied. Children underwent examination an average 2.8 1.3 after On factor analysis four factors found for function: LANG = Language, PS Processing...