A5076753466- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- EEG and Brain-Computer Interfaces
- Health, Environment, Cognitive Aging
- Neural and Behavioral Psychology Studies
- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Visual perception and processing mechanisms
- Psychosomatic Disorders and Their Treatments
- Schizophrenia research and treatment
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Birth, Development, and Health
- Bipolar Disorder and Treatment
- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Neurobiology of Language and Bilingualism
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Suicide and Self-Harm Studies
- Face Recognition and Perception
- Traumatic Brain Injury Research
- Pain Management and Placebo Effect
- Spatial Neglect and Hemispheric Dysfunction
Boys Town
2020-2025
Boys Town National Research Hospital
2020-2025
Creighton University
2022-2025
HumanN (United States)
2023-2024
Icahn School of Medicine at Mount Sinai
2017-2021
Association pour l'Utilisation du Rein Artificiel dans la région Lyonnaise
2021
University of Nebraska Medical Center
2020
Thomas Jefferson University
2012-2017
University of Pennsylvania
2017
Philadelphia University
2017
Spontaneous brain activity was mapped with functional MRI (fMRI) in a sample of 180 subjects while conscious resting-state condition. With the use independent component analysis (ICA) each individual fMRI signal and classification ICA-defined components across subjects, set 23 networks (RNs) identified. Functional connectivity between pair RNs assessed using temporal correlation analyses 0.01- to 0.1-Hz frequency band, corresponding coefficients used obtain hierarchical clustering RNs. At...
Delineating the association of age and cortical thickness in healthy individuals is critical given with cognition behavior. Previous research has shown that robust estimates between brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 aged 3-90 years Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes thickness. We fractional polynomial (FP) regression quantify thickness, computed normalized...
Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies may obscure or distort lifespan trajectories of morphometry. In response, we capitalized resources Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to examine age-related inferred from cross-sectional measures ventricles, basal ganglia...
<h3>Objective:</h3> To characterize the presurgical brain functional architecture presented in patients with temporal lobe epilepsy (TLE) using graph theoretical measures of resting-state fMRI data and to test its association surgical outcome. <h3>Methods:</h3> Fifty-six unilateral TLE, who subsequently underwent anterior lobectomy were classified as obtaining a seizure-free (Engel class I, n = 35) vs not classes II–IV, 21) outcome at 1 year after surgery, 28 matched healthy controls...
Bipolar disorder is a heritable characterized by mood dysregulation associated with brain functional dysconnectivity. Previous research has focused on the detection of risk- and disease-associated dysconnectivity in individuals bipolar their first-degree relatives. The present study seeks to identify adaptive connectivity features resilience, defined here as avoidance illness or delayed onset unaffected siblings patients disorder.Graph theoretical methods were used examine global regional...
The human brain is intrinsically organized into resting-state networks (RSNs). Currently, several functional atlases are used to define the spatial constituents of these RSNs. However, there significant concerns about interatlas variability. In response, we undertook a quantitative comparison five major RSNs (default mode [DMN], salience, central executive, sensorimotor, and visual networks) across currently available (n = 6) in which demonstrated that (a) similarity between was modest...
Alterations in multiple neuroimaging phenotypes have been reported psychotic disorders. However, measures can be influenced by factors that are not directly related to psychosis and may confound the interpretation of case-control differences. Therefore, a detailed characterization contribution these is warranted.To quantify association between behavioral, health, demographic variables using an integrated multivariate approach.This imaging study was conducted at university research hospital...
Mesial temporal lobe epilepsy (MTLE) is the most frequent form of focal epilepsy. At rest, there evidence that brain abnormalities in MTLE are not limited to epileptogenic region, but extend throughout whole brain. It also well established patients suffer from episodic memory deficits. Thus, we investigated relation between functional connectivity seen at rest fMRI and impairments MTLE. We focused on resting state BOLD activity evaluated whether (FC) differences emerge MTL seeds left right...
The functional architecture of resting-state networks (RSNs) is defined by their connectivity and metastability. Disrupted RSN has been amply demonstrated in schizophrenia while the role metastability remains poorly defined. Here, we undertake a comprehensive characterisation organization test its contribution to clinical profile this disorder. We extracted RSNs representing default mode (DMN), central executive (CEN), salience (SAL), language (LAN), sensorimotor (SMN), auditory (AN) visual...
Summary Objective This study determined the ability of resting‐state functional connectivity (rs FC ) graph‐theory measures to predict neurocognitive status postsurgery in patients with temporal lobe epilepsy ( TLE who underwent anterior lobectomy ATL ). Methods A presurgical magnetic resonance imaging (fMRI) condition was collected 16 left and right . In addition, received neuropsychological testing pre‐ verbal nonverbal episodic memory, language, working attention domains. Regarding data,...
Summary Objective In temporal lobe epilepsy ( TLE ), the thalamus is well known for its role in propagation and spread of epileptiform activity. However, integrity thalamocortical functional connectivity FC ) relation to specific seizure patterns have not yet been determined. We address these issues with resting‐state magnetic resonance imaging (f MRI ). Methods Resting‐state f was performed on two groups unilateral patients: those focal seizures only (16 left , 16 right additional...
Elevated body mass index (BMI) is associated with increased multi-morbidity and mortality. The investigation of the relationship between BMI brain organization has potential to provide new insights relevant clinical policy strategies for weight control. Here, we quantified association increasing functional resting-state networks in a sample 496 healthy individuals that were studied as part Human Connectome Project. We demonstrated higher was changes connectivity default-mode network (DMN),...
<h3>Importance</h3> The landscape of tobacco use is changing. However, information about the association between early-age and cognitive performances limited, especially for emerging products such as electronic cigarettes (e-cigarettes). <h3>Objective</h3> To assess initiation measured by National Institutes Health (NIH) Toolbox Cognitive Battery to examine whether associated with differences in brain morphometry. <h3>Design, Setting, Participants</h3> This observational cohort study...
The default mode network (DMN) plays a crucial role in internal self-processing, rumination, and social functions. Disruptions to DMN connectivity have been linked with early adversity the emergence of psychopathology adolescence adulthood. Herein, we investigate how subclinical psychiatric symptoms can impact functional during pubertal transition. Resting-state fMRI data were collected annually from 190 typically-developing youth (9–15 years-old) at three timepoints within-network was...
In temporal lobe epilepsy (TLE), determining the hemispheric specialization for language before surgery is critical to preserving a patient's cognitive abilities post-surgery. To date, major techniques utilized are limited by capacity of patients efficiently realize task. We determined whether resting-state functional connectivity (rsFC) reliable predictor dominance in right and left TLE patients, relative controls. chose three subregions inferior frontal cortex (pars orbitalis, pars...