Christine Löchner
A5086354724- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Eating Disorders and Behaviors
- Body Image and Dysmorphia Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Sexuality, Behavior, and Technology
- Impact of Technology on Adolescents
- Attention Deficit Hyperactivity Disorder
- Advanced Neuroimaging Techniques and Applications
- Mental Health Treatment and Access
- Genetic Associations and Epidemiology
- Mental Health Research Topics
- Suicide and Self-Harm Studies
- Child Abuse and Trauma
- Personality Disorders and Psychopathology
- Botulinum Toxin and Related Neurological Disorders
- Psychosomatic Disorders and Their Treatments
- Genetics and Neurodevelopmental Disorders
- Parkinson's Disease Mechanisms and Treatments
- Social Media and Politics
- LGBTQ Health, Identity, and Policy
- Gender, Feminism, and Media
- Resilience and Mental Health
Stellenbosch University
2016-2025
South African Medical Research Council
2012-2025
University of Southampton
2023-2024
University of California, San Diego
2024
Auckland University of Technology
2024
Far East University
2024
University of Cape Town
2005-2023
Chuncheon Sacred Heart Hospital
2023
Hallym University
2023
University of Cuenca
2023
As a response to the COVID-19 pandemic, many governments have introduced steps such as spatial distancing and "staying at home" curb its spread impact. The fear resulting from disease, 'lockdown' situation, high levels of uncertainty regarding future, financial insecurity raise level stress, anxiety, depression experienced by people all around world. Psychoactive substances other reinforcing behaviors (e.g., gambling, video gaming, watching pornography) are often used reduce stress anxiety...
Childhood maltreatment has diverse, lifelong impact on morbidity and mortality. The Trauma Questionnaire (CTQ) is one of the most commonly used scales to assess quantify these experiences their impact. Curiously, despite very widespread use CTQ, scores its Minimization-Denial (MD) subscale-originally designed a positive response bias-are rarely reported. Hence, little known about this measure. If biases are either common or consequential, current practices ignoring MD scale deserve revision....
The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify attributable all interrogated variants. We have quantified variance liability disease explained by SNPs for two phenotypically-related neurobehavioral disorders, obsessive-compulsive disorder (OCD) and Tourette Syndrome (TS), using GCTA. Our analysis yielded point estimate 0.58 (se = 0.09, p 5.64e-12) TS, 0.37...
Abstract Background Although mental disorders and suicidal thoughts‐behaviors (suicidal thoughts behaviors) are common among university students, the majority of students with these problems remain untreated. It is unclear what barriers to seeking treatment. Aims The aim this study examine future help‐seeking associations clinical characteristics in a cross‐national sample first‐year college students. Method As part World Mental Health International College Student (WMH‐ICS) initiative,...
The effect of persistent symptoms or compensatory processes related to cognitive dysfunction in obsessive-compulsive disorder may contribute brain structure alterations OCD, indicating that age is an important factor evaluating changes gray and white matter volumes.
Although skin picking has been documented in the medical literature since 19th century, only now is it receiving serious consideration as a DSM psychiatric disorder discussions for DSM-5. Recent community prevalence studies suggest that appears to be common many other disorders, with reported prevalences ranging from 1.4% 5.4%. Clinical evaluation of patients entails broad physical and examination, encouraging an interdisciplinary approach treatment. Approaches treatment should include...
The two hemispheres of the human brain differ functionally and structurally. Despite over a century research, extent to which asymmetry is influenced by sex, handedness, age, genetic factors still controversial. Here we present largest ever analysis subcortical asymmetries, in harmonized multi-site study using meta-analysis methods. Volumetric seven structures was assessed 15,847 MRI scans from 52 datasets worldwide. There were sex differences globus pallidus putamen. Heritability estimates,...
Problematic internet use (PIU; otherwise known as Internet Addiction) is a growing problem in modern societies. There scarce knowledge of the demographic variables and specific activities associated with PIU limited understanding how should be conceptualized. Our aim was to identify explore moderating role age gender those associations. We recruited 1749 participants aged 18 above via media advertisements an Internet-based survey at two sites, one US, South Africa; we utilized Lasso...
The rapid advance of the coronavirus COVID-19 pandemic has significantly increased mortality but also demonstrated considerable potential to negatively impact mental health, including in young [1,2].From a public health perspective, guidelines for responding mass trauma and disaster emphasize importance focusing on resilience.In immediate ongoing response, consensus interventions that maintain calm, build community, sustain hope [3,4].
Background College entrance is a stressful period with high prevalence of mental disorders. Aims To assess the role impairment associated 12-month disorders among incoming first-year college students within large cross-national sample. Methods Web-based self-report surveys assessing DSM-IV and health-related (Sheehan Disability Scale) were obtained analyzed from 13,984 (Response = 45.5%), across 19 universities in eight countries. Impairment was assessed following domains: home management,...
<i>Background:</i> There is growing recognition that the anxiety disorders are disabling associated with substantial morbidity and impaired quality of life (QOL). Nevertheless, there have been few studies comparing QOL across these conditions. <i>Sampling Methods:</i> 337 outpatients obsessive-compulsive disorder (OCD; n = 220), panic (PD; 53), or social (SAD; 64) were compared using a number assessment scales to compare objective subjective impairment in QOL. The...
There is relatively little data on the link between childhood trauma and obsessive-compulsive/putative obsessive-compulsive spectrum disorders. The revised Childhood Trauma Questionnaire (CTQ), which assesses physical, emotional, sexual abuse as well physical emotional neglect, was administered to female patients with disorder (OCD; n = 74; age: 36.1 ± 16.3), TTM (n 36; 31.8 12.3), a group of normal controls 31; 21.5 1.0). findings showed significantly greater severity in general, neglect...
Objective: Obsessive-compulsive disorder (OCD) and Tourette's syndrome are highly heritable neurodevelopmental disorders that thought to share genetic risk factors. However, the identification of definitive susceptibility genes for these etiologically complex remains elusive. The authors report a combined genome-wide association study (GWAS) OCD. Method: conducted GWAS in 2,723 cases (1,310 with OCD, 834 syndrome, 579 OCD plus syndrome/chronic tics), 5,667 ancestry-matched controls, 290...