- Ear Surgery and Otitis Media
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Urinary Tract Infections Management
- Pediatric Urology and Nephrology Studies
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Epilepsy research and treatment
- Urological Disorders and Treatments
- Streptococcal Infections and Treatments
- Sinusitis and nasal conditions
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Bacterial Infections and Vaccines
- Neonatal Respiratory Health Research
- Asthma and respiratory diseases
- Congenital Heart Disease Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neonatal and fetal brain pathology
- Fatty Acid Research and Health
- Gut microbiota and health
- Blood Pressure and Hypertension Studies
- Viral gastroenteritis research and epidemiology
- Inflammasome and immune disorders
- Tracheal and airway disorders
University of Oulu
2015-2024
Oulu University Hospital
2014-2024
University of Turku
1984-2016
Center for Special Minimally Invasive and Robotic Surgery
2015
Varsinais-Suomen Sairaanhoitopiiri
2004-2006
Tampere University Hospital
1995-2004
Tampere University
1985-2004
University of Helsinki
1979-2003
Helsinki University Hospital
1999-2003
Finnish Institute of Occupational Health
2003
<h3>Context</h3> Exposure to cardiovascular risk factors during childhood and adolescence may be associated with the development of atherosclerosis later in life. <h3>Objective</h3> To study relationship between measured common carotid artery intima-media thickness (IMT), a marker preclinical atherosclerosis, adulthood. <h3>Design, Setting, Participants</h3> Population-based, prospective cohort conducted at 5 centers Finland among 2229 white adults aged 24 39 years who were examined ages 3...
This report describes the general outline and progress of a multicentre study on risk factors coronary heart disease their determinants in children adolescents. "Cardiovascular Risk Young Finns" comprises cross-sectional 3 to 18-year old subjects 1980, follow-up studies 1983 1986 various parts Finland, 1989 one areas (Turku). The number participants 1980 was 3596 (83.1%) those invited. In 83.2% 77.8% them, respectively, participated. programme has comprised questionnaire data on, for...
Background. Xylitol, a commonly used sweetener, is effective in preventing dental caries. As it inhibits the growth of pneumococci, we evaluated whether xylitol could be acute otitis media (AOM). Design. Altogether, 857 healthy children recruited from day care centers were randomized to one five treatment groups receive control syrup (n = 165), 159), chewing gum 178), 179), or lozenge 176). The daily dose varied 8.4 g (chewing gum) 10 (syrup). design was 3-month randomized, controlled trial,...
ABSTRACT. The paper describes the general outline of a multicentre study on risk factors coronary heart disease (CHD) and their determinants in children various ages different parts Finland. was cross‐sectional one, carried out 1980 five university cities Finland with medical schools 12 rural communities vicinity. randomized sample included an equal number boys girls, aged 3, 6, 9, 12, 15, 18 years, urban population each area. total size 4,320 subjects, these 3,596 participated (83.1 %)....
To examine whether xylitol, which reduces the growth of Streptococcus pneumoniae, might have clinical importance in prevention acute otitis media.A double blind randomised trial with xylitol administered chewing gum.Eleven day care nurseries city Oulu. Most children had problems recurrent media.306 children: 149 sucrose group (76 boys; mean (SD) age 4.9 (1.5) years) and 157 (80 5.0 (1.4) years).Either (8.4 g a day) or (control) gum for two months.The occurrence media antimicrobial treatment...
OBJECTIVE: Urinary tract infections (UTIs) in childhood are considered a risk for chronic kidney disease (CKD), but this association is poorly verified. We wanted to determine the etiologic fraction of UTIs as cause CKD. METHODS: A systematic literature search on between and CKD was conducted, data patients with area 1 tertiary care hospital were reviewed. RESULTS: In our search, we found no among 1576 reviewed cases whom main subsequent However, there 3 results imaging studies not reported....
To follow up a previous retrospective analysis in which we found the use of pacifier to be risk factor for recurrent acute otitis media (AOM).In present prospective study, occurrence AOM and were recorded 845 children attending day care centers during 15-month period.More than three attacks occurred 29.5% younger 2 years using pacifiers 20.6% those not doing so (relative risk, 1.6; 95% confidence interval [CI], 0.6, 4.1); 3 age, figures 30.6% 13.2%, respectively 2.9; CI, 1.2, 7.3). Logistic...
Background: The reasons behind the reported increase in occurrence of childhood atopic sensitization rates are unclear. We wanted to evaluate association between dietary fats, serum fatty acids, and development diseases. Methods: From a longitudinal database population‐based sample, 231 sex‐ age‐matched pairs 1980 154 1986 were chosen, whom we compared data, acid composition, same variables also those who developed disease later did not during 9‐year follow‐up. Results: Examination data for...
Objectives. To evaluate the association between pacifier use and increased occurrence of acute otitis media (AOM) in an intervention trial. Methods. Fourteen well-baby clinics were selected to participate open, controlled cohort study. These paired according number children social classes parents they served. One clinic each pair was randomly allocated for intervention, while other served as a control. The nurses at trained instruct &lt;18 months old limit during their prescheduled...
Although the symptoms of acutely ill child are important both in diagnosis and follow-up acute otitis media (AOM), data about them quite limited. We carried out a prospective survey by collecting information on 354 consecutive children visiting pediatrician, otolaryngologist or general practitioner because any kind to compare with those other infectious diseases. The signs observed at home were recorded parents before visit findings physical examination later physician. AOM was diagnosed 191...
<h3>Objective</h3> To evaluate the efficacy of different antipyretic agents and their highest recommended doses for preventing febrile seizures. <h3>Design</h3> Randomized, placebo-controlled, double-blind trial. <h3>Setting</h3> Five hospitals, each working as only pediatric hospital in its region. <h3>Participants</h3> A total 231 children who experienced first seizure between January 1, 1997, December 31, 2003. The were observed 2 years. <h3>Interventions</h3> All episodes during...
ABSTRACT. A dietary survey was conducted in 1980 connection with the Multicentre Study on Atherosclerosis Precursors Finnish Children five urban and 12 rural communes various parts of Finland. 1,768 children aged 3, 6, 9,12,15 18 years were interviewed using 48 hour recall method. Food consumption, intakes energy 49 nutrients calculated. The most increased successive age groups until 15 years. There only small differences diet belonging to different social classes. Protein accounted for 14 %...
Lectures are good for presenting information and providing explanations, but because they lack active participation have been neglected.Students' experiences were evaluated after exposing them to the use of voting during lectures in their paediatrics course. Questions delivered students taking Thirty-six out total 40 (90%) attended opening lecture, at which first survey concerning previous was performed. Thirty-nine (98%) answered second series questions end course.Most felt that improved...
Objective. Child care outside the home increases children's infections substantially. We have to evaluate possibilities for reducing transmission of by an infection prevention program. Design and methods. A 15-month randomized controlled trial involving 20 day-care centers was conducted efficacy The program introduced in 10 other matched served as controls. Records were made occurrence absences from or work because among children, their parents personnel centers. Results. Both children had...
Xylitol is known to reduce caries by inhibiting the growth of Streptococcus mutans. We hypothesized that xylitol could also affect other nasopharyngeal bacterial flora, which be important when considering respiratory infections caused these bacteria. studied this in vitro adding medium and observed 1 5% reduced markedly alpha-hemolytic streptococci, including S. pneumoniae. It slightly beta-hemolytic streptococci but not Haemophilus influenzae or Moraxella catarrhalis. The inhibitory pattern...