A5001003257- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Pediatric Urology and Nephrology Studies
- Pediatric health and respiratory diseases
- Ear Surgery and Otitis Media
- Respiratory and Cough-Related Research
- Gut microbiota and health
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Influenza Virus Research Studies
- Inflammasome and immune disorders
- Viral gastroenteritis research and epidemiology
- Asthma and respiratory diseases
- Urological Disorders and Treatments
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Neonatal and Maternal Infections
- Child and Adolescent Health
- Antibiotic Use and Resistance
- Bacterial Infections and Vaccines
- Hematological disorders and diagnostics
- Nosocomial Infections in ICU
University of Eastern Finland
2019-2024
Kuopio University Hospital
2019-2024
University of Oulu
2014-2024
Finland University
2024
Triological Society
2021
Impact
2021
Oulu University Hospital
2007-2020
Tampere University
2017-2018
Tampere University Hospital
2017-2018
University of Turku
2016
Background: Social distancing measures are used to reduce the spreading of infection. Our aim was assess immediate effects national lockdown orders due coronavirus disease 2019 (COVID-19) on pediatric emergency room (ER) visits and respiratory tract infections in hospitals nationwide Finland. Methods: This register-based study hospital patient information systems Finnish infectious register. The participants were all patients visiting ER 2 (Kuopio University Hospital, Mikkeli Central...
Respiratory syncytial virus (RSV) causes seasonal epidemics of bronchiolitis among susceptible infants. Surfactant protein A (SP-A), a lung C-type lectin involved in innate host defense, opsonizes RSV and enhances phagocytosis. The candidate gene approach was used to investigate association SP-A polymorphism with susceptibility severe infection. Genotype analysis done for 86 infants infection 95 matched control subjects. significant difference the frequency SP-A2 observed. allele 1A(3)...
Abstract Altogether, 20–30% of women receive intrapartum antibiotic prophylaxis (IAP) to prevent sepsis in infants and 2–5% newborn antibiotics due suspected sepsis. Caesarean section has a long-term impact on the intestinal microbiome but effects perinatal gut vaginally delivered are not well known. We compared IAP, postnatal antibiotics, or their combination emergence antimicrobial resistance controlled study 149 recruited within 24 hours after birth. collected 659 fecal samples, including...
Abstract Social restrictions during the coronavirus disease 2019 pandemic strongly affected epidemiology of influenza and respiratory syncytial virus (RSV). As rhinovirus seemed to spread despite restrictions, we aimed analyze in children pandemic. This register‐based study used data from Finnish Infectious Disease Register. Nationwide findings July 2015 March 2021 were included stratified by age (0–4, 5–9, 10–14). Cumulative 14‐day incidence per 100000 was calculated. Four thousand five...
Social restrictions interrupted the normal respiratory virus circulation in Spring 2020. This report describes pediatric population before and after ended Finland September 2021. We used data from Finnish Infectious Disease Register. Nationwide influenza A B, rhinovirus, severe acute syndrome coronavirus 2 (SARS-Cov-2), syncytial (RSV) findings January 2018 to December Age stratified (0-4, 5-9, 10-14 years) weekly incidences per 100 000 children were calculated. School day-care closures...
Intrapartum antibiotic prophylaxis (IAP) is widely used, but the evidence of long-term effects on gut microbiota and subsequent health children limited. Here, we compared impacts perinatal exposure later courses microbiota.This was a prospective, controlled cohort study among 100 vaginally delivered infants with different exposures: control (27), IAP postnatal antibiotics (24), (22). At 1 year age, performed next-generation sequencing bacterial 16S ribosomal RNA gene fecal samples.Exposure...
Lectures are good for presenting information and providing explanations, but because they lack active participation have been neglected.Students' experiences were evaluated after exposing them to the use of voting during lectures in their paediatrics course. Questions delivered students taking Thirty-six out total 40 (90%) attended opening lecture, at which first survey concerning previous was performed. Thirty-nine (98%) answered second series questions end course.Most felt that improved...
Teaching the principles of scientific research in a comprehensive way is important at medical and dental schools. In many countries training not complete until candidate has presented diploma thesis. The objective this study was to evaluate nature, quality, publication pattern visibility Finnish theses. A total 256 theses University Oulu from 2001 2003 were analysed. Using standardised questionnaire, we extracted several characteristics each We used name student assess whether thesis...
Background: Finland introduced universal rotavirus (RV) vaccination in September 2009, with exclusive use of the pentavalent human-bovine reassortant RV vaccine RotaTeq® and following a schedule at 2, 3 5 months age. This study monitored impact on hospitalizations due to acute gastroenteritis (RVGE). The results first seasons after implementation are presented. Methods: Prospective hospital-based surveillance identified children admitted 2 University Hospitals (Tampere Oulu, Finland), from...
The incidence of invasive group A streptococcus (iGAS) infections varies in time and geographically for unknown reasons. We performed a nationwide survey to assess the population-based rates outcomes children with iGAS infections.We collected data on patients from hospital discharge registries electronic databases microbiological laboratories Finland period 1996-2010. then recorded emm types or serotypes strains. study physician visited all university clinics clinical using same entry...
Objective. As regular administration of xylitol had been effective in preventing acute otitis media (AOM) children, we tested whether administered only at times respiratory infection (ARI) reduces the occurrence AOM. Methods. Healthy children (N = 1277) were recruited from child care centers and randomized after screening with tympanometry to receive either control mixture (n 212), chewing gum 280), 286), or lozenges 287) during an ARI. The trial was double blinded within groups. parents...
The prevention of otitis media, particularly among infants, remains a controversial issue. We evaluated the efficacy insertion tympanostomy tubes with and without adenoidectomy for preventing recurrent acute media (AOM) in young children.We randomly assigned 300 children aged 10 months to 2 years who had AOM groups receiving (Tymp) (n = 100), (TympAde) 100) or neither (Contr) 100). All were followed up 12 months.The primary outcome was intervention failure (2 episodes months, 3 6 persistent...