- Pediatric Pain Management Techniques
- Musculoskeletal pain and rehabilitation
- Cardiac electrophysiology and arrhythmias
- Blood Pressure and Hypertension Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Geographic Information Systems Studies
- Mindfulness and Compassion Interventions
- Heart Failure Treatment and Management
- Pharmacology and Obesity Treatment
- Cardiac Health and Mental Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Land Use and Ecosystem Services
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Historical Geography and Cartography
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Hormonal Regulation and Hypertension
- Lipoproteins and Cardiovascular Health
- Social and Educational Sciences
- Historical Geography and Geographical Thought
Karolinska Institutet
2006-2024
University of Gothenburg
2024
Uppsala University
2000-2021
Karolinska University Hospital
2006-2019
Children's Hospital at Westmead
2015
Westmead Hospital
2015
Sachs' Children and Youth Hospital
2007
Pain and Rehabilitation Medicine
1998-2004
AstraZeneca (Sweden)
1992-1997
In-Q-Tel
1997
Although several studies have illustrated the effectiveness of cognitive behavior therapy (CBT) on adult pain patients, there are few randomized controlled trials children and adolescents. There is particularly a need for pediatric patients who severely disabled by longstanding syndromes. Acceptance Commitment Therapy, as an extension traditional CBT, focuses improving functioning quality life increasing patient's ability to act effectively in concordance with personal values also presence...
Fibromyalgia (FM) is characterized by widespread pain and co-morbid symptoms such as fatigue depression. For FM, medical treatments alone appear insufficient. Recent meta-analyses point to the utility of cognitive behaviour therapy (CBT), but effects are moderate. Within continuous development CBT, empirical support for acceptance commitment (ACT) has increased rapidly. ACT focuses on improving functioning increasing patient's ability act in accordance with personal values also presence...
Interventions based on Cognitive Behavioral Therapy (CBT) are widely used to treat chronic pain, but the brain mechanisms responsible for these treatment effects poorly understood. The aim of this study was validate relevance cortical control theory in response an exposure-based form CBT, Acceptance and Commitment Therapy, patients with pain. Forty-three female diagnosed fibromyalgia syndrome were enrolled a randomized, 12-week, waiting-list controlled clinical trial (CBT n=25; controls...
Abstract Cognitive behavior therapy (CBT) has made important contributions to chronic pain management, but the process by which it is effective not clear. Recently, strong arguments have been raised concerning need for theory driven research e.g. identify mechanisms of change in CBT and enhance effectiveness this type treatment. However, number studies addressing these issues still relatively scarce. Furthermore, arrival varieties with seemingly different targets increases such information....
Although 14% to 42% of people with whiplash injuries end up chronic debilitating pain, there is still a paucity empirically supported treatments for this group patients. In pain management, increasing consensus regarding the importance behavioural medicine approach symptoms and disability. Cognitive behaviour therapy has proven be beneficial in treatment pain. An that promotes acceptance of, or willingness experience, other associated negative private events (e.g. fear, anxiety, fatigue)...
Acceptance of pain and other associated negative private experiences has received increasing attention in recent years. This approach is stark contrast to the traditional reducing or controlling symptoms pain. The empirical support for treatments emphasizing exposure acceptance, such as Commitment Therapy, growing. However, date, few instruments exist assess core processes these types treatments. study describes development preliminary validation Psychological Inflexibility Pain Scale....
For chronic pain of unclear origin (idiopathic), pharmacological therapy is often insufficient. Psychological treatment strategies have been developed and evaluated for adults with pain. However, few such studies are seen youths, to date there limited empirical evidence regarding the effectiveness psychological generalized musculoskeletal syndromes in adolescents. Acceptance commitment (ACT) a development cognitive behaviour emphasizing exposure acceptance. In this pilot study, 14...
Recent developments within CBT have emphasized acceptance rather than control of pain and distress in treatments aimed at improving functioning life quality, but there is still a lack reliable valid instruments to assess relevant processes such interventions. The Psychological Inflexibility Pain Scale (PIPS) was developed target variables exposure oriented treatments. A preliminary validation study resulted two-factor solution with subscales for avoidance cognitive fusion related pain,...
Summary Variables consistent with psychological flexibility mediate the effects of Acceptance and Commitment Therapy-based interventions to improve functioning in patients chronic debilitating pain. Even though are well established treatment pediatric pain, there is a clear need for further development, especially severely disabled patients. However, optimizing effectiveness treatments pain requires clarification mechanisms action. Studies addressing change processes scarce, however,...
Summary This study was designed to assess the effect of time on analgesic a local anaesthetic cream consisting mixture 5% lignocaine and prilocaine. The placebo were compared in double‐blind, randomized 114 children aged 4–17 years, with application times 20 minutes longer. A regression analysis revealed no difference between when less than 60 minutes. cusum test showed that became evident at about Local adverse reactions consisted mainly transient paleness skin, which did not constitute any...
Acceptance of pain and distress has lately appeared as an important factor in determining peoples' ability to restore functioning the presence chronic pain. Although treatments based on cognitive behaviour therapy are beginning incorporate acceptance strategies, there is still a lack reliable valid instruments assess relevant processes such interventions. The Chronic Pain Questionnaire (CPAQ) was originally constructed part development oriented treatment approach for patients. A revised...
The present study in hypertensive men (40-64 years old) with untreated diastolic blood pressure above 100 mm Hg was aimed at investigating whether metoprolol (n = 1,609) given as initial treatment would lower the risk for coronary events (sudden death and myocardial infarction) more effectively than thiazide diuretics 1,625). A substantial part of this arm Heart Attack Primary Prevention Hypertension (HAPPHY) study. HAPPHY a pooling effect different beta-blockers, mainly atenolol, which no...
This work examines the basic structures that determine organization of knowledge and exercise power in postmodern world. Olsson promotes an agenda integrates transcends limited/limiting language mainstream social science human action. By challenging boundaries traditionally separating sociology, geography, political sciences, philosophy, literature cultural theory, creates a new voice for sciences which is used both to say show, as topic analysis mode presentation.
1. The effects of mental stress induced by a colour word conflict test (CWT; n = 9) or 3 h infusions placebo adrenaline (0.4 nmol min−1 kg−1; on platelet function in vivo were studied 16 healthy male volunteers. 2. Platelet was assessed filtragometry technique, which reflects aggregability vivo, and measurements the plasma levels β-thromboglobulin (β-TG) factor 4 (PF4). 3. Adrenaline CWT marked cardiovascular responses as expected. Venous increased from 0.1–0.2 nmol/l at rest to 4.87 ± 0.42...
(1970). Explanation, Prediction, and Meaning Variance: An Assessment of Distance Interaction Models. Economic Geography: Vol. 46, PROCEEDINGS International Geographical Union Commission on Quantitative Methods, pp. 223-233.
This article is an edited transcript of a panel discussion on ‘Space and Spatiality in Theory’ which was held at the Annual Meeting Association American Geographers, Washington, DC, April 2010. In article, map out some challenges for thinking, writing performing spaces 21st century, reflecting upon emergence new ways theorizing space spatiality, relationship between writing, action spacing, distinctive spatialized ontologies (e.g. ‘movement-space’) appear to reflect epistemological...
(1965). Distance and Human Interaction A Migration Study. Geografiska Annaler: Series B, Geography: Vol. 47, No. 1, pp. 3-43.
The purpose of the present pilot study was to explore moderating role basal inflammation on effects behavioral pain treatment in 41 patients with long-standing pain. Baseline pro-inflammatory status moderated outcomes: higher pre-treatment levels Tumor Necrosis Factor (TNF)-α and Interleukin (IL)-6 were related less improvement intensity, psychological inflexibility mental health-related quality life. outcomes improved subgroup that had low cytokines at baseline, while subjects did not....
Objective. Heel lancing has hitherto been the method of choice for screening tests inborn errors metabolism in neonates. Eutectic mixture local anesthetic little, if any, analgesic effect when applied to heel pre- and full-term infants. Today there seems be no practical that effectively alleviates pain caused by lancing. The aim this study was investigate whether other methods, such as venipuncture dorsal side hand, are less painful more efficient than Methods. One hundred twenty healthy,...