A5115604005- Reproductive Biology and Fertility
- Ovarian function and disorders
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Advanced ceramic materials synthesis
- Uterine Myomas and Treatments
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Nanowire Synthesis and Applications
- Fatty Acid Research and Health
- Semiconductor materials and interfaces
- Advanced materials and composites
- Silicon and Solar Cell Technologies
- Advancements in Solid Oxide Fuel Cells
- Neurogenetic and Muscular Disorders Research
- Thin-Film Transistor Technologies
- Nuclear materials and radiation effects
- Sperm and Testicular Function
- Effects and risks of endocrine disrupting chemicals
- RNA modifications and cancer
- Reproductive Health and Technologies
Zhejiang University
2014-2024
Capital Medical University
2008-2024
Anhui Normal University
2024
Sir Run Run Shaw Hospital
2013-2024
National Health and Family Planning Commission
2023-2024
Peking University
2023-2024
Shanghai First Maternity and Infant Hospital
2024
Wenzhou Medical University
2024
First Affiliated Hospital of Wenzhou Medical University
2024
Capital University
2024
Can menstrual stem cells (MenSCs) inhibit myofibroblast differentiation and reverse transforming growth factor β (TGFβ)-mediated activation of phenotypes in human endometrial stromal (ESCs)? MenSCs suppressed reversed TGFβ-mediated phenotypes, which might be associated with the Hippo/TAZ pathway. The potential effect as a cell therapy include attenuation intrauterine adhesions, but underlying mechanisms by exerts these effects are not entirely understood. We evaluated antagonistic on well...
Sirtuin 2 (SIRT2), a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase expressed by oligodendrocytes (OLs), the myelin-producing cells of central nervous system (CNS), is markedly up-regulated during active myelination (Li et al. (2007) J Neurosci 27:2606-2616; Southwood Neurochem Res 32:187-195; Werner 27:7717-7730). SIRT2 component myelin proteome and severely reduced in Plp1 knockout mouse brain, which both proteolipid protein (PLP) DM20 are absent (Werner The mechanisms that...
Are endometriotic mesenchymal stem cells (Ecto-MSCs) involved in the fibrosis of ovarian endometrioma? Ecto-MSCs enhanced fibrotic behavior stromal endometrioma through Wnt/β-catenin pathway by paracrine production transforming growth factor-β1 (TGF-β1) and Wnt1. Endometriosis is characterized ectopic outgrowth endometrial stroma glands surrounded dense fibrous tissues. The pathogenesis endometriosis, especially endometrioma-associated fibrosis, still unknown. We analyzed samples from 15...
: CD39, a key ectonucleotidase that drives adenosine production, acts as critical immunosuppressive checkpoint in cancer. Although it has shown promise therapeutic target, clinical trials are demonstrating the need for more potent targeting approaches. This is driving innovation towards development of novel antibodies and exploration strategic combinations with range immunotherapies.
Penconazole (PEN) is a typical systemic triazole fungicide with cardiac toxic effects. Resveratrol (RES) natural polyphenolic phytochemical antioxidation properties. This study aimed to investigate if RES could protect against PEN-induced cardiotoxicity and determine the underlying mechanisms. Zebrafish embryos were exposed 0, 0.5, 1 2 mg/L of PEN from 4 96 h post fertilization (hpf) developmental toxicity was assessed. Our results showed that decreased hatching rate, survival heart rate...
Pregnant women with gestational diabetes mellitus (GDM) have been reported to higher serum triglyceride (TG) levels during the entire period. However, whether TGs contribute incidence of GDM remains unclear. This study aimed evaluate TG level early first trimester is associated GDM.A prospective single-center cohort was carried out among pregnant (n = 2,949) who received regular antenatal care in Fu Xing Hospital, Capital Medical University, Beijing, China. diagnosed between 24 and 28 weeks....
To evaluate the associations between maternal serum concentrations of high-density lipoprotein cholesterol (HDL-c) throughout pregnancy and neonatal birth weight (BW) small for gestational age (SGA) births. A prospective cohort 2241 pregnant women was followed from recruitment to delivery in three hospitals Beijing, China January 2014 December 2017. Maternal fasting lipids were measured at week 6–12, 16, 24 36. Major outcome BW. The HDL-c BW estimated by linear regression mixed-effects...
To compare the reproductive pregnancy outcomes of pretreatment with long-acting gonadotropin-releasing hormone agonist (GnRH-a) plus replacement therapy (HRT) HRT-only cycles, and investigate differences between single polypectomy multiple polypectomies, one or two doses GnRH-a. This was a retrospective cohort study on patients undergoing who underwent frozen–thawed embryo transfer (FET) from March 2018 to May 2019. They were divided into GnRH-a groups. Each group polypectomies (in...
This retrospective study determined the efficacy of 'freeze-all' embryo strategy in poor ovarian responders undergoing stimulation for vitro fertilization (IVF). A total 559 who met Bologna criteria between January 2012 and December 2014 were included this study: 256 fresh transfer group 303 freeze-all group. Vitrification warming day 3 embryos performed using Cryotop method. The treated with those showed similar live birth rates per cycle (12.1% vs. 16.2%, p = .172) (15.9% 20.9%, .182)....