A5045377939- Immune Cell Function and Interaction
- Liver Disease Diagnosis and Treatment
- T-cell and B-cell Immunology
- Sirtuins and Resveratrol in Medicine
- Cardiac, Anesthesia and Surgical Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- RNA modifications and cancer
- Mycotoxins in Agriculture and Food
- Atrial Fibrillation Management and Outcomes
- Spine and Intervertebral Disc Pathology
- Immunotherapy and Immune Responses
- Cancer-related molecular mechanisms research
- Anesthesia and Pain Management
- Autophagy in Disease and Therapy
- Electrospun Nanofibers in Biomedical Applications
- Plant Pathogens and Fungal Diseases
- RNA Research and Splicing
- Plant-Microbe Interactions and Immunity
- Radiomics and Machine Learning in Medical Imaging
- Nausea and vomiting management
- Hemodynamic Monitoring and Therapy
- Pancreatic function and diabetes
Shanghai Jiao Tong University
2024
State Key Laboratory of Oncogene and Related Genes
2024
Yuhuangding Hospital
2024
Qingdao University
2024
Harvard University
2019-2020
Beth Israel Deaconess Medical Center
2019-2020
University of Pittsburgh
2015-2016
Tsinghua University
2015-2016
Rice bakanae disease (RBD) is a typical seed-borne fungal caused by Fusarium fujikuroi. Prochloraz sterol demethylation inhibitor, which among the most important classes of active ingredients for management RBD. In 2022, total resistance frequency F. fujikuroi to prochloraz in Zhejiang Province was 62.67%. The fitness prochloraz-resistant population lower than that susceptible population, but its pathogenicity slightly stronger. S312T and F511S double mutations Ffcyp51b were detected...
Abstract Macrophage hyperactivation is a hallmark of inflammatory diseases, yet the role alternative polyadenylation (APA) mRNAs in regulating innate immunity remains unclear. In this study, we focused on 3’UTR-APA and demonstrated that Nudt21, crucial RNA-binding component machinery, significantly upregulated various conditions. By utilizing myeloid-specific Nudt21-deficient mice, revealed protective effect Nudt21 depletion against colitis severe hyperinflammation, primarily through...
Abstract Pancreatic islet transplantation is a promising therapy for diabetes, but acute rejection of the islets by host effector T cells has hindered clinical application. In this study, we addressed mechanisms CD8+ cell migration to grafts because interrupting step key preventing rejection. We found that revascularized transplants in mice dependent on non-self Ag recognition rather than signaling via Gαi-coupled chemokine receptors. Presentation donor was necessary migration, whereas...