A5087355775- Diabetes Treatment and Management
- Pharmacology and Obesity Treatment
- Family and Disability Support Research
- Respiratory viral infections research
- Parental Involvement in Education
- Cystic Fibrosis Research Advances
- Obesity, Physical Activity, Diet
- Viral gastroenteritis research and epidemiology
- HIV/AIDS Research and Interventions
- Syphilis Diagnosis and Treatment
- Pharmaceutical Practices and Patient Outcomes
- Hearing Loss and Rehabilitation
- Adolescent Sexual and Reproductive Health
- Radiomics and Machine Learning in Medical Imaging
- HIV, Drug Use, Sexual Risk
- Gastric Cancer Management and Outcomes
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Screening and Detection
- Eating Disorders and Behaviors
- Transplantation: Methods and Outcomes
- Infant Development and Preterm Care
- Machine Learning in Healthcare
- COVID-19 Clinical Research Studies
- Children's Rights and Participation
- Lipoproteins and Cardiovascular Health
Bellevue Hospital Center
2023-2024
University of North Texas
2024
University of Washington
2019-2023
Bellevue College
2023
Medical City Children's Hospital
2020
Children's Medical Center
2020
University of San Simón
2004
Université Libre de Bruxelles
2004
University of North Carolina at Chapel Hill
1999
<h3>Importance</h3> Eating disorders (EDs) are common psychiatric associated with high mortality. However, data on ED disease dynamics and treatment coverage sparse. <h3>Objectives</h3> To model the individual-level of from birth to age 40 years estimate association increased ED-related <h3>Design, Setting, Participants</h3> In this decision analytical study, an Markov state transition was empirically calibrated in April 2019 using a Bayesian approach synthesize available clinical...
This work compares the results of two epidemiologic and clinical surveys on consequences maternal chronic Trypanosoma cruzi infection. They were conducted in 1992–1994 1999–2001 same maternity clinic Bolivia, a country highly endemic for infection with this parasite. In both surveys, materno-fetal transmission parasites occurred 5-6% infected mothers. Maternal T. had no effect pregnancy outcome health newborns when there was parasites. Comparisons between older more recent highlighted...
We interviewed 200 Latino parents (50 Mexican couples, 50 Puerto Rican couples) living in the United States to determine needs and supports related raising a child with disability identify variables reported supports. The pattern of expressed was similar that found previous studies, but number substantially higher. More support from family formal sources than friends or informal sources. Using repeated measures analysis covariance involving six three variables, we English language...
We examine how 150 Latino mothers of young children with developmental disabilities use narratives to express and create self-understandings vis-à-vis their child. The purpose is twofold: (a) introduce narrative as a tool that people make sense disability, (b) demonstrate these draw on cultural beliefs the form construct meanings self in relationship disability. An analysis spontaneous disability reveal majority portrayed themselves good line larger notions, viewed child bringing about...
We interviewed 200 Latino parents of young children with disabilities to determine awareness, use, and satisfaction services. also examined use alternative treatments the relationship between child family variables satisfaction. A high degree awareness was noted but only a moderate found. Mothers were more aware perceived services than fathers. With few exceptions, bore little or No families pursued as their primary source help, although several used them in minor way. Program may be likely...
Dual HIV and syphilis testing might help to prevent mother-to-child transmission (MTCT) of through increased case detection treatment. We aimed model assess the cost-effectiveness dual during antenatal care in four countries with varying prevalence.In this modelling study, we developed Markov models pregnant women estimate costs infant health outcomes maternal at first visit individual tests (base case) a rapid diagnostic test (scenario one). additionally evaluated retesting late delivery...
Abstract Background Limited recent data exist on prescribing patterns and patient characteristics for glucagon-like peptide 1 receptor agonists (GLP-1 RAs), an important drug class used as anti-diabetic medication (ADM) patients with type 2 diabetes mellitus (T2D) and/or anti-obesity (AOM) in overweight or obesity. For brevity, we use the term GLP-1 RA to refer both dual RA/GIP medications. Objective To describe trends dispensing of GLP-1-based medications US. Methods Using a subset...
Body composition metrics such as visceral fat volume, subcutaneous volume and skeletal muscle are important predictors for cardiovascular disease, diabetes, cancer prognosis. Recent advances in artificial intelligence have enabled automatic calculation of body from CT scans MRIs. In this study, we explore using deep learning to estimate chest radiographs a small set variables that easy obtain the clinical environment. A retrospective cohort patients with concurrent non-contrast abdominal...
What is the clinical question being addressed? Heart failure with reduced ejection fraction (HFrEF) a leading cause of morbidity and mortality, guideline-directed medical therapy (GDMT) shown to improve left ventricular (LVEF) outcomes. However, contemporary real-world trajectories LVEF changes following an initial transthoracic echocardiography (TTE) diagnosis HFrEF how these relate patient characteristics, GDMT use, outcomes are not well described. main finding? Repeat assessment occurred...
Background: Limited recent data exist on prescribing patterns and patient characteristics for glucagon-like peptide 1 receptor agonists (GLP-1 RAs), an important drug class used as anti-diabetic medication (ADM) patients with type 2 diabetes mellitus (T2D) and/or anti-obesity (AOM) in overweight or obesity. For brevity, we use the term GLP-1 RA to refer both dual RA/GIP medications. Objective: To describe trends dispensing of GLP-1-based medications US. Methods: Using a subset real-world...
Syphilis incidence has increased significantly in the US, raising concerns about onward transmission. Using near-real-time data, this study examined monthly trends syphilis among US adults from January 2017 to October 2024, focusing on overall patterns and stratifying by demographic clinical characteristics. Truveta Data - a large, diverse database of electronic health records healthcare systems 2024 was calculated. Poisson regression models were used assess trends, with adjustments for...
Introduction Key populations, including female sex workers (FSW), people who inject drugs (PWID), and in serodiscordant partnerships, experience higher HIV incidence compared to the general population. Maternal retesting, particularly during late pregnancy, helps detect new infections prevent vertical transmission, but optimal testing schedules among key populations are unknown. Methods We used a Markov model estimate health economic impacts of maternal retesting on transmission outcomes FSW...
Abstract Background Both tirzepatide and semaglutide have been shown to reduce weight for patients with overweight or obesity in randomized controlled trials (RCTs). While appears provide greater loss than this population, head-to-head RCTs are not yet available. Accordingly, we sought compare on-treatment a real-world setting adults initiated on semaglutide. Methods Adults first dispensed between May 2022 September 2023 were identified from Truveta Data, large electronic health record (EHR)...
Abstract Importance Adherence to GLP-1 RA is important for efficacy. Discontinuation and reinitiation patterns patients with without type 2 diabetes (T2D) are not well-understood. Objective To describe rates factors associated discontinuation of RA, T2D. Design In this retrospective cohort study, adults overweight or obesity initiated on between January 2018 December 2023 were identified using electronic health record (EHR) data from a collective 30 US healthcare systems. Patients followed...
The purpose of this study is to demonstrate three ways analyzing qualitative interview data: content, cultural models, and narrative analyses. We draw upon the same set data with 250 Latino parents young children mental retardation or developmental delay illustrate these types Interwoven analyses are suggestions for in which studies early intervention could be extended by considering different approaches examining data.
Abstract Introduction HIV retesting during late pregnancy and breastfeeding can help detect new maternal infections prevent mother‐to‐child transmission (MTCT), but the optimal timing cost‐effectiveness of remain uncertain. Methods We constructed deterministic models to assess health economic impact on a hypothetical population pregnant women, following initial testing in pregnancy, MTCT four countries: South Africa Kenya (high/intermediate prevalence), Colombia Ukraine (low prevalence)....
Abstract Introduction Chronic kidney disease (CKD) is a highly prevalent with disparities in diagnosis and treatment. Until recently, primary for CKD was based on equations that incorporated race have demonstrated racial bias. This study had two aims comparing outcomes Black patients their counterparts: 1) whether using the new 2021 CKD-EPI equation led to decreased disparity time diagnosis; 2) there discordance staging between at potential point. Methods We evaluated aged 18 over...
Using machine learning to leverage CEA biomarker change and predict colorectal cancer recurrence.
Background Electronic health record (EHR) data contain longitudinal patient information and standardized diagnostic codes. EHR may be useful for estimating transition probabilities state-transition models, but no guidelines exist on appropriate methods. We applied 3 potential methods to estimate from data, using pediatric eating disorders (EDs) as a case study. Methods obtained PEDsnet, which includes 8 US children’s hospitals. Data included inpatient, outpatient, emergency department visits...
Abstract Long COVID, or post-COVID syndrome, is a constellation of symptoms observed in patients at least four weeks after COVID-19 infection. We analyzed the effect vaccination status on risk either developing COVID being diagnosed with COVID. In separate analyses we compared time infection and as time-dependent covariate where could occur any point respect to To address this question, identified subset adult from Truveta Data who experienced indicated by positive laboratory test between...