A5019097089- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Global Cancer Incidence and Screening
- Diverticular Disease and Complications
- Spine and Intervertebral Disc Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal disorders and treatments
- Global Health Care Issues
- Healthcare cost, quality, practices
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Anorectal Disease Treatments and Outcomes
- Aortic aneurysm repair treatments
- Musculoskeletal pain and rehabilitation
- Enhanced Recovery After Surgery
- Aortic Disease and Treatment Approaches
- Mobile Health and mHealth Applications
- Cardiac and Coronary Surgery Techniques
- Blood Pressure and Hypertension Studies
- Medical Imaging and Analysis
- Lung Cancer Research Studies
- Health, Environment, Cognitive Aging
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Multiple and Secondary Primary Cancers
- Hip and Femur Fractures
Royal Prince Alfred Hospital
2025
Stanford Health Care
2025
Stanford University
2025
University of Washington
2014-2024
Seattle University
2015-2022
St. Mary's Medical Center
2021
St. Mary's Hospital
2021
St Mary's Hospital
2021
National Bureau of Economic Research
2021
New York University
2020
IMPORTANCEFunctional impairment and pain are common indications for the initiation of lumbar spine surgery, but information about expected improvement in these patient-reported outcome (PRO) domains is not readily available to most patients clinicians considering this type surgery. OBJECTIVETo assess population-level PRO response after develop/validate a prediction tool improvement. DESIGN, SETTING, AND PARTICIPANTSThis statewide multicenter cohort was based at 15 Washington state hospitals...
Importance Including race and ethnicity as a predictor in clinical risk prediction algorithms has received increased scrutiny, but there continues to be lack of empirical studies addressing whether simply omitting from the will ultimately affect decision-making for patients minoritized racial ethnic groups. Objective To examine including colorectal cancer recurrence algorithm is associated with bias, defined differences model accuracy that could potentially lead unequal treatment. Design,...
The poor in low and middle income countries have limited access to health services due purchasing power, residence underserved areas, inadequate literacy. This produces significant gaps care delivery among a population that has disproportionately large burden of disease. They frequently use the private sector, perceived or actual public services. A subset organizations, some called social enterprises, developed novel approaches increase availability, affordability quality through innovative...
PURPOSE Although financial toxicity is a growing cancer survivorship issue, no studies have used credit data to estimate the relative risk of hardship in patients with versus individuals without cancer. We conducted population-based retrospective matched cohort study using reports investigate impact diagnosis on adverse events (AFEs). METHODS Western Washington SEER registry (cases) and voter (controls) records from 2013 2018 were linked quarterly TransUnion. Controls age-, sex-, zip...
Abstract Background Current treatment of diffuse-large-B-cell lymphoma (DLBCL) includes rituximab, an expensive drug, combined with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy. Economic models have predicted rituximab plus CHOP (RCHOP) to be a cost-effective alternative alone as first-line DLBCL, but it remains unclear what its real-world costs cost-effectiveness are in routine clinical practice. Methods We performed population-based retrospective cohort...
Abstract Background The goal of cytoreductive surgery for peritoneal malignancy is to remove all macroscopic disease, which occasionally requires the excision umbilicus. While absence umbilicus can be aesthetically undesirable patients, umbilical reconstruction rarely performed due perceived complexity and increased risk wound infections (Sakata et al. in Colorectal Dis 23:1153–1157, 2021). This study aims evaluate outcomes, cosmetic results patient satisfaction during surgery. Methods...
Abstract Background Breast cancer screening (BCS) inequities are evident at national and local levels, many health systems want to address these inequities, but may lack data about contributing factors. The objective of this study was inform system interventions through an exploratory analysis potential multilevel contributors BCS using data. Methods authors conducted a cross‐sectional within large academic including 19,774 individuals who identified as Black ( n = 1445) or White 18,329)...
Summary We conducted a multi‐institutional population‐based analysis of the survival and toxicity associated with addition rituximab to chemotherapy for patients diffuse large B‐cell lymphoma ( DLBCL ), including aged ≥80 years, who were excluded from published randomized trials. Using registries in Ontario, we identified 4021 received or without (R‐ CHOP [rituximab cyclophosphamide, doxorubicin, vincristine prednisone] ) between 1996 2007, 397 years. After propensity score matching, overall...
Machine learning is used to analyze big data, often for the purposes of prediction. Analyzing a patient's healthcare utilization pattern may provide more precise estimates risk adverse events (AE) or death. We sought characterize prior surgery using machine prediction.Patients from MarketScan Commercial Claims and Encounters Database undergoing elective 2007-2012 with ≥1 comorbidity were included. All available claims occurring within six months assessed. More than 300 predictors defined by...
Background: Surgical site infection (SSI) after spine surgery is classified as a "never event" by the Centers for Medicare and Medicaid. Intra-wound antibiotics (IWA) have been proposed to reduce incidence of SSI, but robust evidence support its use lacking. Methods: Prospective cohort undergoing fusion at 20 Washington State hospitals (July 2011 March 2014) participating in Spine Care Outcomes Assessment Program (Spine SCOAP) linked discharge tracking system. Patient, hospital, operative...
BackgroundIn response to the COVID-19 pandemic, two new temporary hospitals were constructed in record time Wuhan, China, help combat fast-spreading virus February 2020.Using experience of one hospital as a case study, we discuss health and economic implications this strategy its potential application other countries. MethodsThis retrospective observational study analyzed resource utilization clinical outcomes data for 2011 inpatients diagnosed with admitted Leishenshan Hospital during 67...
Statewide retrospective cohort study using prospectively collected data from the Spine Care and Outcomes Assessment Program, capturing ∼75% of state's spine fusion procedures.The aim this was to estimate variation in patient-reported outcomes (PROs) 1 year after elective lumbar surgery across surgeons hospitals; discuss potential impact guiding patient selection a PRO prediction tool.Despite an increasing interest incorporating PROs as part move toward value-based payment improve quality,...
PURPOSE There is growing interest in using computable phenotypes or proxies to identify important clinical outcomes, such as cancer recurrence, rich electronic health records data. However, the race/ethnicity-specific accuracies of these remain unclear. We examined whether accuracy a proxy for colorectal (CRC) recurrence differed by race/ethnicity and possible mechanisms that drove differences. METHODS Using data from large integrated care system, we identified stratified random sample 282...
Using machine learning to leverage CEA biomarker change and predict colorectal cancer recurrence.
The aim of this study was to evaluate the concordance in grade assignment for gastroenteropancreatic neuroendocrine tumors using mitotic count (MC), Ki-67 proliferative index (KPI), and phosphohistone H3 (PHH3C).Resected were graded based on MC, KPI, PHH3C. Concordance determined a weighted κ statistic. Median survival across each category Kaplan-Meier methods.Of 110 patients, majority had gastrointestinal primaries 1 or 2 tumors. Rates discordance 29% cases KPI versus MC (κW = 0.26), 32%...
Objectives: To identify factors associated with the minimum necessary information to determine an individual's eligibility for lung cancer screening (ie, sufficient risk factor documentation) and characterize clinic-level variability in documentation. Study Design: Cross-sectional observational study using electronic health record data from academic system 2019. Methods: We calculated relative of documentation by patient-, provider-, system-level variables Poisson regression models,...