A5000645208- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- RNA modifications and cancer
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Inflammatory Bowel Disease
- Reproductive System and Pregnancy
- 3D Printing in Biomedical Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Cells and Metastasis
- Graphene and Nanomaterials Applications
- Endometrial and Cervical Cancer Treatments
- Cancer-related gene regulation
- Genetic diversity and population structure
- Ferroptosis and cancer prognosis
- MRI in cancer diagnosis
- Management of metastatic bone disease
- Helicobacter pylori-related gastroenterology studies
- Bone Tissue Engineering Materials
- Forensic Anthropology and Bioarchaeology Studies
- Forecasting Techniques and Applications
- Advanced Radiotherapy Techniques
- Immunotherapy and Immune Responses
- Supply Chain and Inventory Management
Jilin University
2009-2025
Hebei Medical University
2017-2024
Fourth Hospital of Hebei Medical University
2017-2024
Union Hospital
2015-2021
Union Hospital
2016-2017
First Affiliated Hospital of Xinjiang Medical University
2016
Xinjiang Medical University
2016
Abstract Northern China harbored the world’s earliest complex societies based on millet farming, in two major centers Yellow (YR) and West Liao (WLR) River basins. Until now, their genetic histories have remained largely unknown. Here we present 55 ancient genomes dating to 7500-1700 BP from YR, WLR, Amur (AR) regions. Contrary stability AR, YR WLR profiles substantially changed over time. The populations show a monotonic increase time affinity with present-day southern Chinese Southeast...
Abstract 3D scaffolds are essential as they serve extracellular matrix (ECM)‐like platforms to provide cells with mechanical support and facilitate their attachment for bone regeneration. As an emerging personalized treatment technology, printing has been applied treat irregular large‐area defects caused by diseases such tumors trauma. However, traditional methods cannot control the microstructure of tissue engineering (BTE). Meanwhile, commercial materials often cause rejection reactions,...
Background and Aims:Ulcerative colitis (UC) is characterized by Th2-polarized, B cell responses. However, neither size, composition, nor activity of the Breg compartment in active UC has been evaluated.
// Ziqiang Tian 1 , Shiwang Wen Yuefeng Zhang Xinqiang Shi Yonggang Zhu Yanzhao Xu Huilai Lv and Guiying Wang 2 Department of Thoracic Surgery, The Fourth Hospital Hebei Medical University, Shijiazhuang, China Second Correspondence to: Wang, email: tizq12@vip.163.com Keywords: TNM I stage, lung adenocarcinoma, long non-coding RNA, microRNA, RNA-sequencing Received: December 29, 2016 Accepted: May 06, 2017 Published: June 16, ABSTRACT Lung adenocarcinoma (LUAD) is the primary subtype in...
B-cell immunity participates in the pathogenesis of ulcerative colitis (UC). The immune balance between follicular regulatory T (TFR) cells and helper (TFH) is important regulating responses. However, alteration TFR/TFH UC remains unclear. Peripheral blood from 25 patients 15 healthy controls was examined for frequencies circulating TFR, TFH, (Treg) by flow cytometry. Levels serum cytokines were measured using cytometric bead array (CBA). Disease activity evaluated Mayo Clinic Score....
Background: Long noncoding RNA (lncRNA) deleted in lymphocytic leukemia 1 (DLEU1) was reported to be involved the development and progression of multiple cancers. However, accurate expression pattern, biological function potential molecular mechanism DLEU1 glioma are not yet known. The present study investigated role DLEU glioma, as well played by glioma. Materials methods: levels DLEUI tissues cell lines were examined using quantitative real-time PCR. effects on proliferation, mobility,...
Abstract Humoural immunity is crucial for the pathogenesis of ulcerative colitis ( UC ), but precise perturbation B cell poorly understood. This study aimed at evaluating numbers different subsets circulating memory cells, plasmablasts, and levels serum immunoglobulin in patients. Total 23 patients with active 14 healthy controls HC ) were examined cells plasmablasts before after treatment mesalazine 8–12 weeks by flow cytometry. Disease activity was evaluated Mayo clinic score. The...
Abstract Esophageal squamous cell carcinoma (ESCC) is the predominant form with highest incidence. We aimed to find metastasis‐related differentially expressed long noncoding RNAs (lncRNAs), microRNAs (miRNAs), and messenger RNA (mRNAs) in ESCC. first obtained lncRNAs, miRNAs, mRNAs profiles. The were obtained, followed by functional annotation. Then interaction networks of miRNA‐mRNA, lncRNA‐mRNA coexpression, lncRNA‐miRNA, lncRNA‐miRNA‐mRNA constructed. In addition, systematic expression...
Abstract Objective Long noncoding RNA 00460 (LINC00460) has been reported to contribute tumorigenesis in multiple types of human malignancies. However, the biological role and underlying molecular mechanism LINC00460 glioma remain unclear. The aim this study was investigate clinical value, function, potential glioma. Methods expression level tissues cell lines examined by quantitative real‐time polymerase chain reaction (qRT‐PCR). Cell Counting Kit‐8, flow cemetery, wound healing, transwell...
Long noncoding RNA (LncRNA) SBF2-AS1 was reportedly to function as an oncogene in several types of cancers, such hepatocellular carcinoma, nonsmall cell lung cancer, glioma, and colorectal cancer. However, the biological roles regulatory mechanisms gastric cancer (GC) are unknown.The expression miR-545 were examined GC tissues lines via real-time quantitative PCR. The relationship with verified dual-luciferase reporter gene assay immunoprecipitation. influences on proliferation, migration,...
Contents Although clear advances have been made in understanding of gene transcriptional regulation the corpous luteum (CL) during oestrous cycle, little is known about involvement microRNAs (miRNAs) this physiological process. In present study, expression miR‐126‐3p was preliminarily detected bovine CL throughout while middle or late stages significantly more abundant (p < 0.01) than that early regressed stages. Localization subsequently observed large and small luteal cells cycle...
In the random requirement environment, safety stock is necessary to maintain a certain customer service level. High will increase cost of storage. The influence factors are level, average and standard deviation lead time, in time. We know that relates closely time through analyzing model. model analysis showed extent various : When fixed, with level increases, increases sharply while higher than 0.95. random, changing, levels change, but ranges different.
Long non-coding RNA (lncRNA) U731166 and microRNA (miR)-3607-3p are two ncRNAs with critical roles in cancer biology, while their involvement esophageal squamous-cell carcinomas (ESCC) is unclear. We predicted that miR-3607-3p might interact each other. This study aimed to investigate role interaction ESCC. was therefore conducted explore the of ESCC, a focus on between them. Paired ESCC non-tumor tissue samples were recruited from 72 patients. By RT-Qpcr, level paired tissues measured....
Objective To compare target volume and dosimetry between computed tomography(CT)-and magnetic resonance imaging(MRI)-guided three-dimensional(3D)conformal brachytherapy for locally advanced cervical cancer, to provide evidence optimization of the image-guided approach improvement treatment regimen. Methods Thirteen patients with cancer who were treated radical radiotherapy in our hospital 2014 enrolled as subjects. All received MRI-guided 3D conformal intracavitary/interstitial...
Objective To explore the correlation between dose measured in rectum and reference three-dimensional brachytherapy (3DBT) for cervical cancer, to evaluate significance of rectum. Methods Fifty patients receiving radiotherapy cancer were selected, 3DBT was performed after pelvic external beam radiotherapy. According rectal monitoring method recommended report ICRU38, vivo applied obtain rectum, point (DICRU), D2 cm3, planned obtained from planning system. The differences these values...