A5001944531- Global Maternal and Child Health
- Malaria Research and Control
- Mosquito-borne diseases and control
- Substance Abuse Treatment and Outcomes
- Child Nutrition and Water Access
- Homelessness and Social Issues
- Child and Adolescent Psychosocial and Emotional Development
- Community Health and Development
- Prenatal Substance Exposure Effects
- Health Policy Implementation Science
- Global Health and Epidemiology
- Pressure Ulcer Prevention and Management
- Chronic Lymphocytic Leukemia Research
- COVID-19 Impact on Reproduction
- Autoimmune and Inflammatory Disorders Research
- Iron Metabolism and Disorders
- Rheumatoid Arthritis Research and Therapies
- Mental Health Treatment and Access
- Youth Development and Social Support
- Maternal Mental Health During Pregnancy and Postpartum
- HIV/AIDS Impact and Responses
- Complement system in diseases
- Hemoglobinopathies and Related Disorders
- Healthcare Systems and Reforms
University of Bergen
2021-2025
Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with dihydroartemisinin-piperaquine reduces this risk. We developed mathematical model describing the daily incidence uncomplicated requiring among 0-5-year old children hospitalised SMA. fitted to multicentre clinical PDMC using Bayesian methods modelled potential impact across...
Severe malaria poses a significant challenge to under-five children in Malawi, leading high rates of hospitalization and mortality. The World Health Organization has recently recommended post-discharge chemoprevention (PDMC) as preventive strategy for with severe anaemia malaria-endemic regions. In response this recommendation, Malawi's Ministry (MoH) plans implement PDMC nationwide. To facilitate effective implementation, the MoH partnered Training Research Unit Excellence (TRUE) conduct...
Background The provision of post-discharge malaria chemoprevention (PMC) in children recently admitted with severe anemia reduces the risk death and re-admissions endemic countries. main objective this trial was to identify most effective method delivering dihydroartemesinin-piperaquine recovering from anemia. Methods This a 5-arm, cluster-randomized among under-5 hospitalized at Zomba Central Hospital Southern Malawi. Children were randomized receive three day treatment doses monthly...
Abstract Background Infections are one of the leading causes death in neonatal period. This trial aims to evaluate if provision alcohol-based hand rub (ABHR) pregnant women for postnatal household use prevents severe infections (including sepsis, diarrhoea, pneumonia, or death) among infants during first three months. Methods Through a cluster-randomised eastern Uganda, 72 clusters randomised 2-arm design with rural villages as units randomisation. We estimate include total 5932 at 34 weeks...
Abstract Background Mental and neuropsychological disorders make up approximately 14% of the total health burden globally, with 80% affected living in low- middle-income countries (LMICs) whom 90% cannot access mental services. The main objective TREAT INTERACT study is to adapt, implement, evaluate impact a novel, intersectoral approach prevent, identify, refer, treat problems children through user centred task-sharing implementation intervention, inspired by World Health Organization (WHO)...
Background Following a finding of alcohol use among children aged 5–8 years old in Mbale, Uganda, this project investigates the magnitude and substance ged 6–13 related household, community, school, health system clinical factors. Methods The includes four larger work packages (WPs). WP1 comprises management, WP2 3 include scientific components WP4 integration results, dissemination, policy implementation advice. This protocol presents planned research WP 2 3. adaptation validation screening...
<title>Abstract</title> Background Mental and neuropsychological disorders make up approximately 14% of the total health burden globally, with 80% affected living in low- middle-income countries (LMICs) whom 90% cannot access mental services. The main objective TREAT INTERACT study is to adapt, implement, evaluate impact a novel, intersectoral approach prevent, identify, refer, treat problems children through user centered task-sharing implementation intervention, inspired by World Health...
<title>Abstract</title> adolescents are affected through own or other’s drinking. Schools have an opportunity to address this issue. While curriculum-based alcohol education is a widely used educational approach, there limited research on its delivery and effectiveness in Ugandan primary schools. This study aimed explore the teachers’ learners’ perspectives teaching methods <bold>Methods:</bold> was qualitative which enrolled six schools from Mbale, Eastern Uganda. We conducted twelve key...
Chemoprevention with antimalarials is a key strategy for malaria control in sub-Saharan Africa. Three months of postdischarge chemoprevention (PDMC) reduces malaria-related mortality and morbidity pre-school children recently discharged from hospital following recovery severe anemia. Research on adherence to preventive scarce. We aimed investigate the predictors caregivers' three courses monthly PDMC Malawi. used data cluster randomized implementation trial Malawi (n = 357). Modified Poisson...
ABSTRACT To evaluate the cost effectiveness of six disease modifying anti-rheumatic drug (DMARD) treat-to-target treatment strategies for patients with rheumatoid arthritis in Zanzibar. A Markov model was used to calculate cost-effectiveness various DMARD over a three-year period. health-provider perspective and only outpatient costs were considered. The Clinical Disease Activity Index (CDAI) utilized measurement efficacy values obtained from literature. Quality Adjusted Life Years (QALYs)...
Abstract Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) reduces this risk. We developed mathematical model describing the daily incidence uncomplicated requiring among 0-5 year-old children hospitalised SMA. fitted to multicentre clinical PDMC using Bayesian methods. then modelled potential impact across malaria-endemic African...