A5101696855- Malaria Research and Control
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Ophthalmology and Eye Disorders
- Liver Disease and Transplantation
- Signaling Pathways in Disease
- Antibiotic Resistance in Bacteria
- Drug-Induced Hepatotoxicity and Protection
- Plant and animal studies
- Endodontics and Root Canal Treatments
- Ocular Disorders and Treatments
- Connective tissue disorders research
- Foreign Body Medical Cases
- Pediatric Hepatobiliary Diseases and Treatments
- Breast Cancer Treatment Studies
- Educational Challenges and Innovations
- COVID-19 epidemiological studies
- Complement system in diseases
- Diverse Scientific Research Studies
- Ethnobotanical and Medicinal Plants Studies
- Nanocomposite Films for Food Packaging
- Comparative Animal Anatomy Studies
- Coal and Its By-products
- Medical Malpractice and Liability Issues
- Neurological Complications and Syndromes
Government Medical College
2023-2025
Nanyang Technological University
2020-2024
Manubhai Patel Dental College and Hospital
2024
New York University
2022
Sardar Patel Medical College
2018-2021
International Centre for Genetic Engineering and Biotechnology
2017
Kothiwal Dental College and Research Centre
2016
International Centre for Genetic Engineering and Biotechnology
2013-2015
Jawaharlal Nehru University
2015
National Botanical Research Institute
2014
Intercellular adhesion molecules (ICAMs) belong to the immunoglobulin superfamily and participate in diverse cellular processes including host–pathogen interactions. ICAM-1 is expressed on various cell types macrophages, whereas ICAM-4 restricted red blood cells. Here we report identification of an 11-kDa synthetic protein, M5, that binds human ICAM-4, as shown by vitro interaction studies, surface plasmon resonance immunolocalization. M5 greatly inhibits invasion macrophages erythrocytes...
Southeast Asia has been the hotbed for development of drug-resistant malaria parasites, including those with resistance to artemisinin combination therapy. While mutations in kelch propeller domain (K13 mutations) are associated resistance, a range evidence suggests that other factors critical establishment and subsequent transmission field. Here, we perform quantitative analysis DNA damage repair parasite Plasmodium falciparum find strong link between enhanced resistance. This experimental...
Tuberculosis (TB) is one of the most prevalent infectious diseases affecting millions worldwide. The currently available anti-TB drugs and vaccines have proved insufficient to contain this scourge, necessitating an urgent need for identification novel drug targets therapeutic strategies. disruption crucial protein-protein interactions, especially those that are responsible virulence in Mycobacterium tuberculosis – example ESAT-6:CFP10 complex a worthy pursuit direction. We therefore sought...
Invasion of human erythrocytes by Plasmodium falciparum merozoites involves multiple interactions between host receptors and their merozoite ligands. Here we report Cyclophilin B as a receptor for PfRhopH3 during invasion. Localization binding studies show that is present on the binds strongly to merozoites. We demonstrate RBCs treatment with Cyclosporin A prevents also multi-protein complex involving Basigin, well PfRh5 aids Furthermore, identification de novo peptide CDP3 blocks invasion...
Concerns about adverse reactions and the development of antibiotic resistance have prompted an alternative treatment strategy that utilizes traditional medicinal herbs.
ABSTRACT Strabismus fixus convergens is a condition in which both eyes become fixed extreme adduction. It can be congenital or acquired. We report case of strabismus high myope with primary amyloidosis localized to the lateral rectus muscle. To our knowledge, this first secondary amyloidosis.
Background The search for molecules against Mycobacterium tuberculosis is urgent. mechanisms facilitating the intra-macrophage survival of are as yet not entirely understood. However, there evidence showing involvement host cell cytoskeleton in every step establishment and persistence mycobacterial infection. Methodology/Principal Findings Here we show that expression ARPC4, a subunit Actin related protein 2/3 (Arp2/3) complex, severely affects pathogen's growth. TEM studies display shedding...
Practicing wheat-maize cropping system by the farmers of Himachal Pradesh is less economical viable as compared to pulses. Besides this, pulses have high potential soil improvement through nitrogen fixation. Hence, experiment was premeditated evaluate carbon stock and economic profitability cereals under Harar Aonla based agroforestry systems in low hill zone Pradesh. The conducted with nine treatment combinations four replications RBD. Highest biomass (77.80 t ha-1) (38.05 were recorded...
Tuberculosis (TB) is a huge global burden, with new and resistant strains emerging at an alarming rate, necessitating urgent need for class of drug candidates. Here, we report that SL3, novel 33-amino acid peptide, causes debilitating effects on mycobacterial morphology. Treatment SL3 drastically inhibits the growth Mycobacterium tuberculosis in vitro as well pre-clinical mouse model M.tb infection. Microarray analysis SL3-expressing strain demonstrates wide-scale transcriptional disruption...
In the buffalo carotid body is located in periarterial connective tissue of occipital artery immediately cranial to bifurcation common artery. The lobulated and does not appear contain chromaffin tissue. Nerve terminals have been seen close relation glomus cells. A quantitative study fibre content nerve has also made. myelinated fibres range from 278 473, with a mean 386 ± 39 fibres. histogram distinctly unimodal. Of population, 55.4% diameters 2 <i>µ</i>m, 34.1% 4 9.5% 6...
The chairless chair is a kind of ergonomical product which actually that based on exoskeleton support. primary work behavior workers who have been listed as prolonged occupational standing reported the worst health outcomes. A small study concluded there stands higher chance significant and lower limb muscle fatigue while five hours or more than day. This might increase risk for long-term back pain musculoskeletal disorders. In mean time, researchers found people primarily stand at are...
Multiple canals in the root are part of normal morphology tooth. A canal may sometimes be overlooked, however, and this lead to failure treatment. The first step successful endodontic treatment, therefore, is gaining access pulp chamber locating all canals. In order achieve goal, practitioners need familiar with possible variations morphology, should thoroughly explore roots ensure that identified, debrided, obturated. Here, we report diagnosis, treatment planning, management a maxillary...
Malaria is the most prevalent infectious diseases in world. This study aims to assess correlation of hepatorenal dysfunction malaria patients pediatric age group.This was conducted on admitted Department Paediatrics, PBM hospital, Bikaner (Rajasthan), during resurgence various outbreaks year 2011 and 2012. The diagnosis confirmed by examination thick thin smear/optimal test; malarial hepatic renal were included study.The mean with and/or 5-10 years preponderance males. Association between...