A5101972529- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Anesthesia and Neurotoxicity Research
- Biochemical effects in animals
- Peroxisome Proliferator-Activated Receptors
- Lipid metabolism and biosynthesis
- Hydrogen's biological and therapeutic effects
- Food Waste Reduction and Sustainability
- Protein Hydrolysis and Bioactive Peptides
- Pharmacological Effects of Natural Compounds
- Agriculture Sustainability and Environmental Impact
- Animal Genetics and Reproduction
- Biomarkers in Disease Mechanisms
- Inflammatory Bowel Disease
- Cytokine Signaling Pathways and Interactions
- Insect-Plant Interactions and Control
- Monoclonal and Polyclonal Antibodies Research
- Ginger and Zingiberaceae research
- Gastrointestinal motility and disorders
- Ruminant Nutrition and Digestive Physiology
- Ginseng Biological Effects and Applications
- S100 Proteins and Annexins
- Insect Utilization and Effects
- Seaweed-derived Bioactive Compounds
- Enhanced Recovery After Surgery
Yanbian University
2014-2025
Luye Pharma (China)
2022
Chungbuk National University
2021
Hebei University
2019-2020
To investigate the anti-inflammatory effects of collagen peptides, peptides from cod skin were prepared to assess their in vitro and vivo efficacy against ulcerative colitis. The results show that demonstrated by inhibiting secretion pro-inflammatory cytokines reducing oxidative stress vitro. In vivo, significantly reduced colonic tissue damage, modulated serum cytokine balance, increased expression tight junction proteins ZO-1, Occludin, Claudin-1 colon tissue, enhanced abundance beneficial...
Genetic polymorphisms have a great impact on enhancing quantitative traits in cattle. In this study, Fatty acid synthase (FASN) g. 16024 (A>G), Stearoyl-CoA desaturase (SCD) 10329 (C>T), and pleomorphic adenoma gene (PLAG1) 25003338 (C>G) genotypic allelic were evaluated, along with their associations fatty composition, adipogenic expression, carcass characteristics (carcass weight, yield grade, backfat thickness, marbling score) Hanwoo steers. A total of 128 steers selected for...
Constipation arising from the poor bowel movement is a rife enteric health problem. Shouhui Tongbian Capsule (SHTB) traditional Chinese medicine (TCM) which effectively improve symptoms of constipation. However, mechanism has not been fully evaluated. The purpose this study was to evaluate effect SHTB on and intestinal barrier mice with Our data showed that improved constipation induced by diphenoxylate, confirmed shorter first defecation time, higher internal propulsion rate fecal water...
Although advanced gastric cancer has many limitations and response rate is marginal in chemotherapy. Overexpression of human epidermal growth factor receptor 2(HER-2/neu) gene its protein are associated with increased cell division a high tumor have been reported several malignancies. Especially, approximately 30% breast patients overexpression HER-2/neu the metastasize faster, induces resistance chemotherapy down-regulate function estrogen receptor. Recombinant humanized anti-HER2 antibody...
Intramuscular fat (IMF) is closely related to the tenderness, juiciness, and flavor of beef, an important indicator for beef quality assessment internationally. The main components skeletal intramuscular are phospholipids triacylglycerols (TAG), final step TAG biosynthesis catalyzed by diacylglycerol acyltransferase 2 (DGAT2). To explore effect DGAT2 on differentiation bovine muscle satellite cells (BSCs) its role in signaling pathway lipid metabolism, adenovirus overexpression interference...
Triacylglycerol (TGA) is the primary component of intramuscular fat. Expression diacylglyceryl transferase (DGAT) determines polyester differentiation ability precursor adipocytes. The two DGAT isoforms (DGAT1 and DGAT2) play different roles in TAG metabolism. This study investigates DGAT1 DGAT2 signaling pathways related to lipid metabolism Yanbian bovine preadipocytes. sh-DGAT1 (sh-1), sh-DGAT2 (sh-2), + (sh-1 2) were prepared using short interfering RNA (siRNA) interference technique...
Background: Hydrogen has been shown to exert a bioactive effect on the myocardium. This study examined signalling pathways for hydrogen attenuating ischaemia-reperfusion injury. Methods: In total, 20 male Wistar rats were evaluated effects of hydrogen-rich water in hearts. Left ventricular tissue was taken screening and analysis active protein factors by chip technology. The enrichment KEGG pathway obtained using Gene Ontology (GO) principle. expression JAK2, STAT1, STAT3, p-STAT1, p-JAK2,...
The effects of hydrogen-rich water on PI3K/AKT-mediated apoptosis were studied in rats subjected to myocardial ischemia-reperfusion injury (MIRI). Methdos: Sixty divided randomly into a group and control group. hearts removed fixed Langendorff device. Hearts from the perfused with K-R solution, was solution + water. two treatment groups then pre-ischemic period, ischemic period reperfusion groups(10 per group), which reverse perfusion for 10 min, normal 20 respectively. mRNA protein...
Abstract This study investigated the effects of dietary exogenous glucose oxidase (GOD) and/or catalase (CAT) on intestinal antioxidant capacity and barrier function in piglets under oxidative stress. Sixty pigs assigned randomly to five treatment groups—CON: basal diet; DIQ: GOD: diet + 40‐U GOD/kg CAT: 50‐U CAT/kg GC: diet—were analyzed. On Day 14, CON group was injected with saline, others were treated diquat. The results showed that diquat‐treated piglets, supplementation GOD CAT...
Poor quality straw can be made more digestible and palatable through delignification using white rot fungi as a biological treatment in SSF. The decomposition of organic matter by is improved when carbon source added. Reducing the fermentation cycle also help retain nutrients feed. To increase rumen digestibility nutrient utilization, corn rice were subjected to SSF with (Phanerochaete chrysosporium) for 21 days. type (glucose, sucrose, molasses, or soluble starch) was optimized, composition...
Objective: To develop an efficient method for extracting gelatin from Yanbian cattle skin and to study its anti‐inflammatory effects. Methods: Gelatin was extracted using enzymatic hydrolysis water extraction techniques. The basic structures of the prepared were analyzed Fourier transform infrared spectroscopy (FT‐IR), ultraviolet (UV) spectroscopy, amino acid analysis, scanning electron microscopy (SEM), matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF...
Triacylglycerols (TAGs) are a major component of intramuscular fat. Diacylglycerol O-acyltransferase 2(DGAT2) expression determines the rate TAG synthesis. The purpose this study was to investigate role DGAT2 in differentiation Yanbian cattle preadipocytes and lipid metabolism-related signalling pathways. Bovine were infected with overexpression interfering adenovirus vectors DGAT2. effects on examined using molecular transcriptomic techniques, including differentially expressed genes (DEGs)...
Skeletal muscle satellite cells have the ability to differentiate into various under different conditions. This study aimed investigate effects of concentrations oleic acid (50, 100, and 200 µmol/L) on process lipogenic transdifferentiation in Yanbian bovine cells, as well its molecular regulatory mechanism. After inducing differentiation with for 96 h, it was observed that addition resulted formation lipid droplets triglyceride content showed a dose-dependent relationship concentration OA....
We hypothesized that the unsaturated fatty acid palmitoleic (POA) could promote expression of adipogenic/lipogenic genes in bovine skeletal muscle satellite cells (BSCs). The BSCs were cultured a growth medium containing 10% fetal serum. When reached 80%–90% confluence, we used differentiation with 5% horse serum for 96 h. contained 50 µM, 100 µM and 200 POA. Control BSC only media. Compared control BSC, POA significantly up-regulated paired box 3 (Pax3) 7 (Pax7) down-regulated myogenin gene...
Background: The differentially expressed proteins (DEPs) involved in the effect of hydrogen-rich water on myocardial ischemia reperfusion injury (MIRI) and their biological processes signaling pathway were analyzed. Methods: 20 Wistar rats randomly equally divided into a control group. Hearts removed fixed Langendorff device. group was perfused with K-R solution, solution + water. Protein extracted from ventricular tissues, GSR-CAA-67 used to identify DEPs between two groups. analyzed...
Ciglitazone is a member of the thiazolidinedione family, and specifically binds to peroxisome proliferator-activated receptor-γ (PPARγ), thereby promoting adipocyte differentiation. We hypothesized that ciglitazone as PPARγ ligand in absence an differentiation cocktail would increase adiponectin adipogenic gene expression bovine satellite cells (BSC). Muscle-derived BSCs were isolated from six, 18-month-old Yanbian Yellow Cattle. The BSC cultured for 96 h medium containing 5 µM (CL), 10...
Cell-cultured meat, as a new type of meat food, can effectively mitigate the negative effects conventional animal husbandry on environment, health and welfare. Muscle stem cells are main seed for production cell-cultured but their weak proliferative capacity in vitro severely limits large-scale low-cost meat. There is growing evidence that L-ascorbic acid (AA) has ability to increase efficiency muscle cell proliferation differentiation vitro. However, role AA Yanbian bovine skeletal...