A5100773841- Glycosylation and Glycoproteins Research
- Neuroscience and Neuropharmacology Research
- Polysaccharides and Plant Cell Walls
- Mast cells and histamine
- Cancer, Hypoxia, and Metabolism
- Liver Disease Diagnosis and Treatment
- Neurotransmitter Receptor Influence on Behavior
- Pain Mechanisms and Treatments
- Ion channel regulation and function
- COVID-19 Clinical Research Studies
- Caveolin-1 and cellular processes
- Lung Cancer Treatments and Mutations
- Hepatitis B Virus Studies
- Horticultural and Viticultural Research
- Wine Industry and Tourism
- Galectins and Cancer Biology
- Receptor Mechanisms and Signaling
- Seaweed-derived Bioactive Compounds
- Neuropeptides and Animal Physiology
- Phytochemical Studies and Bioactivities
- Fermentation and Sensory Analysis
- Sperm and Testicular Function
- Pharmaceutical Practices and Patient Outcomes
- Food Allergy and Anaphylaxis Research
- Polysaccharides Composition and Applications
Daping Hospital
2023-2025
Army Medical University
2023-2025
Shaanxi Normal University
2012-2025
Ministry of Agriculture and Rural Affairs
2021-2025
Chinese Academy of Fishery Sciences
2014-2025
Guangdong Academy of Medical Sciences
2025
Southern Medical University
2025
Guangdong Provincial People's Hospital
2025
Huazhong University of Science and Technology
2009-2024
National Institutes of Health
2016-2024
On March 11, 2020, the World Health Organization declared its assessment of coronavirus disease 2019 (COVID-19) as a global pandemic. However, specific anti-severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) drugs are still under development, and patients managed by multiple complementary treatments. We performed retrospective analysis to compare evaluate effect low molecular weight heparin (LMWH) treatment on progression. For this purpose, clinical records laboratory indicators...
Drought is one of the most severe abiotic factors restricting plant growth and yield. Numerous genes functioning in drought response are regulated by abscisic acid (ABA) dependent independent pathways, but knowledge interplay between two pathways still limited. Here, we integrated transcriptome sequencing network analyses to explore interplays ABA-dependent ABA-independent responding stress Arabidopsis thaliana. We identified 211 differentially expressed (DEGs) 1,118 DEGs under stress....
Summary Background On March 11, 2020, the World Health Organization declared its assessment of COVID-19 as a global pandemic. However, specific antiviral drugs are still unavailable, and pateints managed by multiple complementary treatments. Methods The electronic medical records patients where basic information, complete blood count, coagulation profile, inflammatory cytokines serum biochemical indicators in 42 with (21 whom were treated low molecular weight heparin (LMWH), 21 without LMWH)...
The purpose of this work was to ameliorate the yield polysaccharides from Kangxian flowers (PKFs) using ultrasonic-assisted extraction (UAE) and explore structural features cosmetic potential PKFs obtained under optimized UAE. According response surface methodology, optimal UAE for were liquid-to-solid ratio 59: 1 mL/g, ultrasonic power 404 W, time 48 min, temperature 66℃, which reached 26.8 ± 1.76 %, 2.6-folds higher than hot-water extraction. By comparing microstructures, it can be seen...
Introduction The precise detection of weeds in the field is premise implementing weed management. However, similar color, morphology, and occlusion between wheat pose a challenge to weeds. In this study, CSCW-YOLOv7 based on an improved YOLOv7 architecture was proposed identify five types complex fields. Methods First, dataset constructed for that are commonly found, namely, Descurainia sophia , thistle, golden saxifrage, shepherd’s purse herb, Artemisia argyi . Second, model called achieve...
Understanding the diversity and evolution of microorganisms during wine fermentation is essential for controlling its production. However, flavors profiles associated with microbiota changes spontaneous have not yet been described in detail. In this study, we explored correlations between microbial community physicochemical properties flavor components Cabernet Sauvignon wine. Microbial at different stages was identified using high-throughput sequencing, volatile compounds were through...
To discover novel antioxidants and anticoagulants for the prevention treatment of cardiovascular diseases remains ongoing concern. Sagittaria trifolia is a commonly consumed aquatic vegetable with highly nutritious value wide planting area in China. Polysaccharides are major bioactive constituents, but little information available on anticoagulant potential. In this work, polysaccharide from S. (PST) was modified by sulfation to produce four sulfated derivatives (SPST-1 ∼ 4), their...
The dynamic interplay between tyrosine kinase inhibitors (TKIs) and the tumor immune microenvironment (TME) plays a crucial role in therapeutic trajectory of non-small cell lung cancer (NSCLC). Understanding functional dynamics resistance mechanisms TKIs is essential for advancing treatment NSCLC.
Abstract Acquired resistance to osimertinib (Osi) remains a major obstacle in the treatment of patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). AXL elevation is known key mechanism Osi‐resistance, and therapeutic strategies remain scarce. Emerging evidence reveals that an increased intracellular glutathione (GSH) level induces Osi resistance. In this study, new identified by which GSH regulates expression via peroxidase 4 (GPX4) Osi‐resistant cells. A multifunctional covalent...
Abstract Soft-shelled turtles, or Trionychia, are an enigmatic and fascinating group due to their specific morphological features ecological adaptations. Based on mitochondrial DNA (mtDNA) and/or nuclear markers, previous studies showed the incongruent phylogenetic topologies within Trionychia (e.g., Palea its closely related species). In order resolve equivocal relationships obtain some “genome-level” common evolutionary characters of soft-shelled in this study, we assembled annotated...
ABSTRACT Purpose This study employed a two‐sample Mendelian randomization (MR) approach to investigate the bidirectional relationship between brain‐derived neurotrophic factor (BDNF) and major depressive disorder (MDD), addressing gaps left by prior observational studies. Methods We utilized Genome‐Wide Association Study (GWAS) datasets, including MDD information from Psychiatric Genomics Consortium (PGC) UK Biobank ( N = 500,199), along with plasma BDNF measurements FinnGen 619). In...