Fan Zhang

ORCID: 0000-0003-3095-2507
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About
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Research Areas
  • Plant Disease Resistance and Genetics
  • Plant Pathogens and Resistance
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Plant Virus Research Studies
  • Adsorption and biosorption for pollutant removal
  • GABA and Rice Research
  • Microbial Metabolism and Applications
  • Legume Nitrogen Fixing Symbiosis
  • Photosynthetic Processes and Mechanisms
  • Pharmacological Effects of Natural Compounds
  • Silicon Effects in Agriculture
  • Nanomaterials for catalytic reactions
  • Rice Cultivation and Yield Improvement
  • Yeasts and Rust Fungi Studies
  • Plant Molecular Biology Research
  • Protist diversity and phylogeny
  • Biomarkers in Disease Mechanisms
  • Identity, Memory, and Therapy
  • Neurological Disorders and Treatments
  • Plant and Fungal Interactions Research
  • Veterinary medicine and infectious diseases
  • Covalent Organic Framework Applications
  • China's Socioeconomic Reforms and Governance

Nanjing Agricultural University
2011-2025

Sichuan Agricultural University
2022-2025

China Agricultural University
2020-2024

Jilin University
2022-2024

Yunnan Academy of Agricultural Sciences
2023

Peking University
2023

Soochow University
2023

Chinese Academy of Agricultural Sciences
2012-2022

Sun Yat-sen University
2022

China University of Geosciences
2022

In plants and animals, nucleotide-binding leucine-rich repeat (NLR) proteins are intracellular immune sensors that recognize eliminate a wide range of invading pathogens. NLR-mediated immunity is known to be modulated by environmental factors. However, how pathogen recognition NLRs influenced factors such as light remains unclear. Here, we show the agronomically important NLR Rpi-vnt1.1 requires confer disease resistance against races Irish potato famine Phytophthora infestans secrete...

10.1073/pnas.2002759117 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2020-04-13

Intercellular communication via gap junctions, comprised of connexin (Cx) proteins, allow for between astrocytes, which in turn is crucial maintaining CNS homeostasis. The expression Cx43 decreased post-mortem brains from patients with major depression. A potentially novel mechanism tricyclic antidepressants to increase the and functioning junctions astrocytes.The effect amitriptyline on junction intercellular (GJIC) rat primary cultured cortical astrocytes was investigated. We also...

10.1111/bph.12614 article EN British Journal of Pharmacology 2014-02-24

Filamentous plant pathogen genomes often display a bipartite architecture with gene-sparse, repeat-rich compartments serving as cradle for adaptive evolution. The extent to which this two-speed genome is associated genome-wide DNA modifications unknown. We show that the oomycetes Phytophthora infestans and sojae possess functional adenine N6-methylation (6mA) methyltransferases modulate patterns of 6mA marks across genome. In contrast, 5-methylcytosine could not be detected in these species....

10.1186/s13059-018-1564-4 article EN cc-by Genome biology 2018-10-31

Late blight, caused by the oomycete plant pathogen Phytophthora infestans, is a destructive disease that leads to significant yield loss in potatoes and tomatoes. The introgression of resistance (R) genes, which encode nucleotide-binding domain leucine-rich repeat-containing receptors (NLRs), into cultivated potatoes, highly effective controlling late blight. Here, we generated transgenic 2R 3R potato lines stacking R genes Rpi-blb2/Rpi-vnt1.1 Rpi-vnt1.1/RB/R8, respectively, susceptible cv....

10.1111/jipb.13892 article EN Journal of Integrative Plant Biology 2025-03-24

The color of the walnut seed coat is a critical determinant its market value; however, research into mechanisms responsible for formation yet to be determined. Using two clones with contrasting pale-yellow and light purple coats, we characterized pigmentation, particularly anthocyanin content, using spectrophotometry. We then conducted integrated transcriptomic metabolomic analyses identify molecular pathways underlying their formation. content in clone was significantly greater than that...

10.3390/f16040691 article EN Forests 2025-04-16

Sensitivities of Phytophthora capsici to fluopicolide were investigated in vitro, with results showing that had strong inhibitory activities on each development stage P. capsici, particular the motility zoospore. The potential resistance risk for was evaluated. baseline sensitivities 146 isolates obtained from 28 provinces China initially determined, and 50% inhibition mycelial growth (EC50) distribution a unimodal curve mean 0.17 μg/ml. A series fluopicolide-resistant mutants by fungicide...

10.3389/fmicb.2020.00185 article EN cc-by Frontiers in Microbiology 2020-03-03

Late blight, caused by the oomycete Phytophthora infestans, is a major constraint on production of potatoes and tomatoes as well constant threat to global food security. An early diagnostic tool important for effective management late blight in field. Here, combination with simplified DNA extraction method, we developed lateral flow strip-based recombinase polymerase amplification (LF-RPA) assay rapid, equipment-free detection P. infestans. This targets Ras-related protein (Ypt1) gene can be...

10.1094/pdis-01-20-0203-sc article EN other-oa Plant Disease 2020-05-12

10.1016/j.jtice.2016.05.019 article EN Journal of the Taiwan Institute of Chemical Engineers 2016-05-29

Histone acetylation is a dynamic modification process co-regulated by histone acetyltransferases (HATs) and deacetylases (HDACs). Although HDACs play vital roles in abiotic or biotic stress responses, their members Triticumaestivum response to plant viruses remain unknown. Here, we identified characterized 49 T. aestivumHDACs (TaHDACs) at the whole-genome level. Based on phylogenetic analyses, TaHDACs could be divided into 5 clades, protein spatial structure was integral conserved....

10.3390/plants10010019 article EN cc-by Plants 2020-12-24

Oomycetes are a group of filamentous microorganisms that include some the biggest threats to food security and natural ecosystems. However, much molecular basis pathogenesis development in these organisms remains be learned, largely due shortage efficient genetic manipulation methods. In this study, we developed modified transformation methods for two important oomycete species, Phytophthora infestans Plasmopara viticola , bring destructive damage agricultural production. As part established...

10.1371/journal.ppat.1011346 article EN cc-by PLoS Pathogens 2023-04-21

ABSTRACT The pervasive use of social media among adolescents has been linked to various aspects their development, encompassing both beneficial and detrimental effects. However, the precise mechanisms through which influences adolescent development remain underexplored. This study seeks elucidate associations between flourishing Chinese adolescents, employing a strength‐based perspective that integrates comparison theory identity theory. In this research, 786 aged 11–19 years participated by...

10.1111/cfs.13232 article EN Child & Family Social Work 2024-09-19

Phytophthora infestans, the causal agent of Irish Potato Famine in 1840s, is one most destructive crop pathogens that threaten global food security. Host resistance (R) genes may help to control disease, but recognition by through gene products can be evaded newly emerging isolates. Such isolates are dangerous as they cause disease outbreaks under favorable conditions. However, our lack knowledge about adaptation these jeopardizes an apt response breakdown. Here we performed genome and...

10.1094/phyto-05-20-0208-fi article EN other-oa Phytopathology 2020-10-07

Using data from the China Health and Nutrition Survey (CHNS) dated 1991 to 2015, we assess impact of public bus expansion into villages on income mobility rural household, particularly, with low income. This paper finds that low-income households is suffered buses in areas. Due ‘crowding out’ effect, families are excluded non-agricultural employment brought by expansion, which nevertheless does not improve agricultural production structure. can explain why group has been marginalized during...

10.1080/00036846.2023.2216438 article EN Applied Economics 2023-05-24

To reduce the fermentation cost for industrialization of chlorothalonil hydrolytic dehalogenase (Chd), agro-industrial wastewaters including molasses, corn steep liquor (CSL) and wastewater were used to substitute expensive carbon nitrogen sources fresh water lab preparation.The results showed that molasses CSL could replace 5% source 100% organic respectively maintain same level. Re-fermentation from raffinate ultra-filtered achieve 61.03% initial Chd activity reach 96.39% when cultured in...

10.1002/jsfa.8079 article EN Journal of the Science of Food and Agriculture 2016-10-13

Background: The antigens encoded by human leukocyte antigen (HLA) genes are primary in immunological response of transplantation, and genotypes HLA-A, B DRB1 must be determined on donors recipients before the transplantation is carried out. In this study, oligonucleotide microarray for HLA-AB genotyping was prepared evaluated. Methods: Oligonucleotide probes were designed based sequence different HLA-A fixed silylated glass slides to form a microarray. Fluorescence-labeled target DNA...

10.2217/14622416.7.7.973 article EN Pharmacogenomics 2006-10-01

Abstract NHC‐stabilized dichlorosilaimine ArN=Si(I i Pr)Cl 2 ( ) (Ar = 2,6‐ Pr C 6 H 3 , I 1,3‐diisopropyl‐4,5‐dimethylimidazol‐2‐ylidene) and disilane LSiHCl‐SiCl L (L=ArNSiMe could be synthesized from the reaction of aminodichlorosilane ArN(SiMe )SiHCl 1 with under different conditions. This represents first route to generation donor‐stabilized substituted chlorosilane in presence an NHC via dehydrosilylation.

10.1002/cjoc.201600719 article EN Chinese Journal of Chemistry 2017-03-05

Abstract Filamentous plant pathogen genomes often display a bipartite architecture with gene sparse, repeat-rich compartments serving as cradle for adaptive evolution. However, the extent to which this “two-speed” genome is associated genome-wide epigenetic modifications unknown. Here, we show that oomycete pathogens Phytophthora infestans and sojae possess functional adenine N6- methylation (6mA) methyltransferases modulate patterns of 6mA marks across genome. In contrast, 5-methylcytosine...

10.1101/217646 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2017-11-11
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