A5067499963- Genetics, Bioinformatics, and Biomedical Research
- Protein Structure and Dynamics
- Enzyme Structure and Function
- Bioinformatics and Genomic Networks
- vaccines and immunoinformatics approaches
- Advanced Proteomics Techniques and Applications
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- Machine Learning in Bioinformatics
- Computational Drug Discovery Methods
- Biomedical and Engineering Education
- Monoclonal and Polyclonal Antibodies Research
- Animal Behavior and Welfare Studies
- SARS-CoV-2 detection and testing
- Primate Behavior and Ecology
- Mosquito-borne diseases and control
- HER2/EGFR in Cancer Research
- Genomics and Phylogenetic Studies
- Digital Storytelling and Education
- Wildlife Ecology and Conservation
- Scientific Computing and Data Management
- 3D Printing in Biomedical Research
- Bacteriophages and microbial interactions
- COVID-19 epidemiological studies
Worldwide Protein Data Bank
2015-2025
TD Bank
2020-2025
Universidade Federal de Mato Grosso
2025
Rutgers, The State University of New Jersey
2014-2024
University of Kent
2024
Scripps Research Institute
2021
Rutgers Sexual and Reproductive Health and Rights
2020
University of California, San Diego
2014
San Diego Supercomputer Center
2014
Kyoto University
2014
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), the US data center global PDB archive and a founding member of Worldwide partnership, serves tens thousands depositors in Americas Oceania makes 3D macromolecular structure available at no charge without restrictions to millions RCSB.org users around world, including >660 000 educators, students members curious public using PDB101.RCSB.org. include structural biologists crystallography,...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center global PDB archive, serves thousands of Depositors in Americas and Oceania makes 3D macromolecular structure available at no charge without usage restrictions to more than 1 million rcsb.org Users worldwide 600 000 pdb101.rcsb.org education-focused around globe. include structural biologists using crystallography, nuclear magnetic resonance spectroscopy electron microscopy....
The Protein Data Bank (PDB) is the single global archive of experimentally determined three-dimensional (3D) structure data biological macromolecules. Since 2003, PDB has been managed by Worldwide (wwPDB; wwpdb.org), an international consortium that collaboratively oversees deposition, validation, biocuration, and open access dissemination 3D macromolecular data. Core Archive houses atomic coordinates more than 144 000 structural models proteins, DNA/RNA, their complexes with metals small...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, http://rcsb.org), the US data center global PDB archive, makes freely available to all users, from structural biologists computational and beyond. New tools resources have been added RCSB web portal in support of a 'Structural View Biology.' Recent developments improved User experience, including high-speed NGL Viewer that provides 3D molecular visualization any browser, file download enhanced organization...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide (wwPDB), is US data center open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB also responsible security. Annually, serves >10 000 depositors three-dimensional (3D) biostructures working on all permanently inhabited continents. delivers from its research-focused RCSB.org web portal to many millions consumers based in virtually every United Nations-recognized...
Abstract Analyses of publicly available structural data reveal interesting insights into the impact three‐dimensional (3D) structures protein targets important for discovery new drugs (e.g., G‐protein‐coupled receptors, voltage‐gated ion channels, ligand‐gated transporters, and E3 ubiquitin ligases). The Protein Data Bank (PDB) archive currently holds > 155,000 atomic‐level 3D biomolecules experimentally determined using crystallography, nuclear magnetic resonance spectroscopy, electron...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, Institutes of Health, and Department Energy, has served structural biologists (PDB) data consumers worldwide since 1999. RCSB PDB, a founding member Worldwide (wwPDB) partnership, is center global PDB archive housing biomolecular structure data. also responsible security data, as wwPDB-designated Archive Keeper. Annually, serves tens thousands three-dimensional...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) provides open access to experimentally-determined three-dimensional (3D) structures of biomolecules. RCSB PDB RCSB.org research-focused web portal is used annually by many millions users around the world. They biostructure information, run complex queries utilizing various search services (e.g., full-text, structural and chemical attribute, chemical, sequence, structure similarity searches), visualize...
The Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank (PDB) supports scientific research and education worldwide by providing access to annotated information about three-dimensional (3D) structures of macromolecules (e.g., nucleic acids, proteins), associated small molecules drugs, cofactors, inhibitors) in the PDB archive. Researchers, educators, students use RCSB resources study shape interactions biological their implications molecular biology, medicine,...
The Research Collaboratory for Structural Bioinformatics (RCSB) Molecule of the Month series provides a curated introduction to 3-D biomolecular structures available in Protein Data Bank archive and tools that are at RCSB website accessing exploring them. A variety educational materials, such as articles, videos, posters, hands-on activities, lesson plans, curricula, build on this use settings general key topics, enzyme action, protein synthesis, viruses. associated materials freely www.rcsb.org.
The Protein Data Bank (PDB) archive is a rich source of information in the form atomic-level three-dimensional (3D) structures biomolecules experimentally determined using macromolecular crystallography, nuclear magnetic resonance (NMR) spectroscopy, and electron microscopy (3DEM). Originally established 1971 as resource for protein crystallographers to freely exchange data, today PDB data drive research education across scientific disciplines. In 2011, online portal PDB-101 was launched...
Abstract Now in its 52nd year of continuous operations, the Protein Data Bank (PDB) is premiere open‐access global archive housing three‐dimensional (3D) biomolecular structure data. It jointly managed by Worldwide (wwPDB) partnership. The Research Collaboratory for Structural Bioinformatics (RCSB PDB) funded National Science Foundation, Institutes Health, and US Department Energy serves as data center wwPDB. RCSB PDB also responsible security role wwPDB‐designated Archive Keeper. Every...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, RCSB.org), the US Worldwide (wwPDB, wwPDB.org) data center global PDB archive, provides access to via its RCSB.org research-focused web portal. We report substantial additions tools and visualization features available at RCSB.org, which now delivers more than 227000 experimentally determined atomic-level three-dimensional (3D) biostructures stored in archive alongside 1 million Computed Structure Models...
Understanding the molecular evolution of SARS-CoV-2 virus as it continues to spread in communities around globe is important for mitigation and future pandemic preparedness. Three-dimensional structures proteins those other coronavirusess archived Protein Data Bank were used analyze viral proteome during first 6 months COVID-19 pandemic. Analyses spatial locations, chemical properties, structural energetic impacts observed amino acid changes >48 000 isolates revealed how each one 29 have...
Abstract Three-dimensional structures of SARS-CoV-2 and other coronaviral proteins archived in the Protein Data Bank were used to analyze viral proteome evolution during first six months COVID-19 pandemic. Analyses spatial locations, chemical properties, structural energetic impacts observed amino acid changes >48,000 sequences showed how each one 29 study have undergone changes. Structural models computed for every unique sequence variant revealed that most substitutions map protein...
In addition to providing open access >220,000 experimentally-determined three-dimensional (3D) structures of biological macromolecules stored in the Protein Data Bank archive (PDB), Research Collaboratory for Structural Bioinformatics (RCSB PDB) research-focused web portal (RCSB.org) serves >1 million Computed Structure Models (CSMs, predicted protein structures) generated using AlphaFold2 (from AlphaFold DB) or RoseTTAFold2/AlphaFold2 ModelArchive). All PDB and CSMs made...
Two illustrations integrate current knowledge about severe acute respiratory syndrome (SARS) coronaviruses and their life cycle. They have been widely used in education outreach through free distribution as part of a coronavirus-related resource at Protein Data Bank (PDB)-101, the portal RCSB PDB. Scientific sources for creation examples dissemination response are presented.
Abstract Summary: The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) resource provides tools query, analysis and visualization of the 3D structures in PDB archive. As mobile Web is starting to surpass desktop laptop usage, scientists educators are beginning integrate devices into their research teaching. In response, we have developed RCSB Mobile app iOS Android platforms enable fast convenient access data services. Using app, users from general public...
Knowledge about the structure and function of biomolecules continues to grow exponentially, enabling us “see” structural snapshots biomolecular interactions functional assemblies. At PDB-101, educational portal RCSB Protein Data Bank, we have taken a storytelling approach make this body knowledge accessible comprehensible wide community students, educators, general public. For over 20 years, Molecule Month series has utilized traditional illustrated that is regularly adapted for classroom...
Abstract The Protein Data Bank (PDB) was established in 1971 as the first open-access digital data resource biology. Beginning with only seven protein structures, PDB archive has ballooned to >170,000 structures of proteins, DNA, and RNA (totaling >1 billion atoms). Today, is universally regarded a core science fundamental importance wider life-science community long-term preservation machine-readable biological data. are molecules life. Knowledge 3D (shapes) biomolecules, how they evolve...
Molecular origami offers an offline way to explore the 3D structures of biology. Visit PDB101.rcsb.org download free paper models DNA, green fluorescent protein, viruses, and more. Structural studies provide unique windows into biological world, revealing at atomic level molecular mechanisms that orchestrate processes life. Biomolecular structure can be daunting, however, with its incredible complexity. The Research Collaboratory for Bioinformatics Protein Data Bank (RCSB PDB,...
Abstract The Asian tapir Tapirus indicus is the only species in Southeast Asia. It declining across its range and categorized as Endangered on IUCN Red List. forests of Sumatra are critical to conservation they contain some last remaining populations species, yet efforts hindered by a lack information habitat suitability. We collated camera-trap data from nine landscapes 69,500 km 2 Sumatran rainforest help predict suitable for tapirs island. Predictions Bayesian occupancy models...
Abstract Communication and collaboration are key science competencies that support sharing of scientific knowledge with experts non‐experts alike. On the one hand, they facilitate interdisciplinary conversations between students, educators, researchers, while on other improve public awareness, enable informed choices, impact policy decisions. Herein, we describe an undergraduate course focused using data from various bioinformatics resources to explore molecular underpinnings diabetes...