A5102758560- Cannabis and Cannabinoid Research
- GABA and Rice Research
- Cholinesterase and Neurodegenerative Diseases
- Biological Activity of Diterpenoids and Biflavonoids
- Psoriasis: Treatment and Pathogenesis
- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Allergic Rhinitis and Sensitization
- Phytochemicals and Antioxidant Activities
- Education, Psychology, and Social Research
- Dermatology and Skin Diseases
- Botanical Research and Chemistry
- Urinary Bladder and Prostate Research
- Computational Drug Discovery Methods
- Monoclonal and Polyclonal Antibodies Research
- Phytochemistry and Biological Activities
- Cutaneous lymphoproliferative disorders research
- Pharmacology and Obesity Treatment
- Sinusitis and nasal conditions
- Bioactive Natural Diterpenoids Research
- Pharmacogenetics and Drug Metabolism
- Nicotinic Acetylcholine Receptors Study
- Nuts composition and effects
- Advanced Biosensing Techniques and Applications
- Plant Parasitism and Resistance
University of Ljubljana
2012-2025
Institute of Oncology Ljubljana
1996
Rutin is an antioxidant with many interesting pharmacological effects. It can also be found in buckwheat (Fagopyrum esculentum Moench). UV radiation stimulates the activity of enzymes phenylpropanoid pathway and there some evidence that it influences rutin content plants. The aim present research was (1) to examine influence different levels UV‐B on (2) compare results obtained by three analytical methods. plants were grown under levels: reduced, ambient enhanced, simulating 17% ozone...
Abstract Lipids are important components in human nutrition; however, their increased intake contributes to the development of obesity and can lead multiple long‐term complications. Pancreatic lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is a key enzyme for absorption dietary triglycerides. Interference with fat hydrolysis results reduced utilization ingested lipids, therefore inhibition lipases decreases absorption. Extracts from 106 species medicinal plants, vegetables fruits were...
Hemp (Cannabis sativa L.) cannabinoids and terpenoids have therapeutic effects on human animal health. Cannabis plants can often a relatively high heterogeneity, which leads to different phenotypes that chemical profiles despite being from the same variety. Little information exists about cannabinoid terpenoid in hemp within For this study, 11 three varieties (“Carmagnola” selected (CS), “Tiborszallasi” (TS), “Finola” selection (FS)) were analyzed. The components of essential oil (29)...
The popularity of herbal medicine continues to increase in modern health care practices; therefore, it is imperative recognize and address potential risks associated with its everyday use. Asteraceae family one the most extensively utilized medicinal plant families due abundance diversity bioactive secondary metabolites. aim this article review current understanding allergic significant species belonging family. This various search engines, including PubMed Central, Cochrane Google Scholar,...
The 74 samples of six HYPERICUM species (H. PERFOROTUM, H. HIRSUTUM, MACULATUM, TETRAPTERUM, MONTANUM, AND HUMIFUSUM) were collected around Slovenia and analysed for the content ten substances (rutin, hyperoside, isoquercetin, quercitrin, quercetin, I3,II8-biapigenin, amentoflavone, pseudohypericin, hypericin, hyperforin). flowers separately from green parts plants (herbs). highest most was found in PERFOROTUM. Among herbal (without flowers), MONTANUM HIRSUTUM contained significantly higher...
Quality control of dried plant material in assessments suitability herbal medicinal products is extreme importance. Commonly used procedures for identification species are time consuming and expensive. The development multivariate statistical methods has enabled application vibrational spectroscopy establishing membership.To determine which infrared mode gives most informative spectra identification.Different modes were applied investigation differences among Epilobium Hypericum species:...
Abstract Cannabidiol (CBD) is a pharmacologically active ingredient for use in medical, cosmetic, and food products. CBD forms from cannabidiolic acid (CBDA) with the process of decarboxylation by heating cannabis ( Cannabis sativa L.) material. During production CBD-rich material, should be performed precise conditions regarding temperature time. The experiments were hemp samples at 100, 110, 120, 130, 140 °C 180 min. Materials sampled every 20 min cannabinoid content was analyzed using...
Discovery and development of new antibiotics is still very important because the constant appearance drug-resistant pathogenic bacteria. The broth microdilution test was applied for screening antibacterial activity in extracts higher endophytic fungi. Among tested extracts, three possessed significant activity: mushrooms Amanita virosa. (Fr.) Bertill. (Amanitaceae) Cortinarius praestans. Cordier (Cortinariaceae) against Pseudomonas aeruginosa. Staphylococcus aureus., respectively, extract...
Acetylcholinesterase (AChE) is responsible for the hydrolysis of acetylcholine in neuromuscular junction and other cholinergic synapses. Insight into mechanisms controlling AChE expression skeletal muscle important understanding formation, plasticity, various dysfunctions junction. We have investigated decreased activity fast rat sternomastoideus after chronic glucocorticoid treatment. Under such conditions muscles become atrophic loose 30−40 % their activity. In order to establish at which...
The aim of this study was to test the extract from silver fir wood (Belinal) on reduction blood glucose concentrations after consumption a standard meal. 31 healthy participants consumed 100 g white bread 4 times (with 1 week washout period, consequently) concomitantly with capsule Belinal, chestnut extract, placebo or acarbose (active control). Glucose and insulin in were measured before area under curve concentration meal 35 % lower when Belinal added compared group (p = 0.019). Acarbose...
Rocket is a popular salad vegetable used all over the world and it has many health benefits. However, like with plant material, there exists danger of contamination toxic substances. In case rocket, groundsel occurred. Groundsel common weed in rocket crops, contains very pyrrolizidine alkaloids. our study infrared spectroscopy was to distinguish samples from leaves. Infrared simple analytical technique; however, some specific conditions are more easily implemented industrial environment than...
Silver fir (Abies alba) bark extract contains a mixture of bioactive polyphenols. We tested their effectiveness in the treatment psoriasis order to further investigate potential topical anti-inflammatory activity polyphenols by means randomized, double-blind, placebo-controlled add-on clinical trial, after having examined ability downregulate expression IL-1β cytokine monocyte/macrophage primary cell culture. 61 patients with mild met inclusion criteria and were willing comply protocol...
The article presents the recommendations for managing patients with rhinitis in Slovenia. It covers treatment of allergic and non-allergic rhinitis, as well rhinosinusitis or without nasal polyps. also addresses allergy management, use allergen immunotherapy, its effect on symptom reduction. national are based international guidelines offer a comprehensive overview pharmacological non-pharmacological options these conditions. emphasizes importance clinical decision-making, patient healthcare...
Hemp (Cannabis sativa L., subsp. sativa) contains cannabinoids that are of increasing scientific interest, the most known among them cannabidiol (CBD) and (-)-trans-Δ9-tetrahydrocannabinol (Δ9-THC) with therapeutic activities [1]. Fifteen varieties common hemp from 'Common catalogue agricultural plant species' were analyzed: Fedora 17, KC Dora, Monoica, USO 3, Helena, Santhica 27, Tisza, Tiborszallasi, Antal, Carmagnola, Finola, Kompolti hibrid TC, Ferimon, Novosadska, Marina. Contents...