A5055974508- Analytical Chemistry and Chromatography
- Phase Equilibria and Thermodynamics
- Traditional Chinese Medicine Analysis
- Spectroscopy and Chemometric Analyses
- Chromatography in Natural Products
- Natural product bioactivities and synthesis
- Spectroscopy Techniques in Biomedical and Chemical Research
- Metabolomics and Mass Spectrometry Studies
- Fungal Biology and Applications
- Essential Oils and Antimicrobial Activity
- Plant biochemistry and biosynthesis
- Pharmacological Effects of Natural Compounds
- Ginger and Zingiberaceae research
- Phytochemicals and Antioxidant Activities
- Advanced Chemical Sensor Technologies
- Proteins in Food Systems
- Biological and pharmacological studies of plants
- Food Quality and Safety Studies
- Cancer Treatment and Pharmacology
- Mesoporous Materials and Catalysis
- Eicosanoids and Hypertension Pharmacology
- Reproductive Biology and Fertility
- Microencapsulation and Drying Processes
- Polymer Foaming and Composites
- Alkaloids: synthesis and pharmacology
Nanjing University
2025
Nanjing General Hospital of Nanjing Military Command
2025
Sun Yat-sen University
2015-2024
Center for High Pressure Science and Technology Advanced Research
2019-2023
Guangdong Pharmaceutical University
2020
Industrial Research Institute
1997
Oocyte aging is closely related to a decline in female fertility, accompanied by increased reactive oxygen species levels and changes protein posttranslational modifications. However, the role of palmitoylation oocyte has not been investigated. In present study, new association between redox oocytes was found. We found that level palmitoyl-protein thioesterase 1 (PPT1), depalmitoylation enzyme, maternally aged mice follicular fluid (age >35 years) patients with decreased ovarian reserve...
Gastrodia elata (G. elata) Blume is widely used as a health product with significant economic, medicinal, and ecological values. Due to variations in the geographical origin, soil pH, content of organic matter, levels physiologically active ingredient contents G. from different origins may vary. Therefore, rapid methods for predicting origin these ingredients are important market. This paper proposes visible-near-infrared (Vis-NIR) spectroscopy technology combined machine learning. A variety...
Antimicrobial medicine and food packages based on bio-based film containing essential oils have attracted great attention worldwide. However, the controlled release of from these nanocomposites is still a big challenge. In this study, long-term antibacterial nanocomposite composed zein cinnamon oil (CEO) loaded MCM-41 silica nanoparticles was prepared. The CEO into particles via modified supercritical impregnation efficiently with high drug load (>40 wt%). morphologies prepared were...
Biocompatible skin wound dressing materials with long-term therapeutic windows and anti-infection properties have attracted great attention all over the world. The cooperation between essential oil non-toxic or bio-based polymers was a promising strategy. However, inherent volatility chemical instability of most ingredients in oils make sustained pharmacological activity oil-based biomaterials challenge. In this study, kind film nanocomposite loaded patchouli (PEO-FNC) fabricated. PEO-loaded...
Diabetes is a chronic metabolic disease, whereas α-glucosidases are key enzymes involved in the metabolism of starch and glycogen. There long history use mulberry leaf (the Morus alba) as an antidiabetic herb China, we found that chalcomoracin, one specific Diels-Alder adducts leaf, had prominent α-glucosidase inhibitory activity has potential to be substitute for current hypoglycemic drugs such acarbose, which have severe gastrointestinal side effects. In this study, chalcomoracin was...
It is still controversial whether poor aqueous solubility the most primary reason for low oral bioavailability of insoluble drugs. Therefore, in this study, berberine-loaded solid polymeric particles (BPs) varied dissolution profiles with β-cyclodextrin (β-CD) as carrier were fabricated using solution-enhanced dispersion by supercritical fluids (SEDS), and relationship between berberine (BBR) was evaluated. Dissolution property controlled via particle morphology manipulation, which achieved...
Sexual problems are widespread and adversely affect the interpersonal relationships quality of life. Currently, synthetic drugs improving sexual function available, but expenditures for such agents extremely high. To discover relatively inexpensive, widely available effective natural drugs, we identified a combined extracts from Lepidium meyenii (maca) root Allium tuberosum Rottl. (Chinese chive) seed, assessed effects this on erectile dysfunction, explored its potential mechanisms. The were...
A rapid quantitative analytical method for three components of Lonicerae Japonicae Flos solution (Lonicera Japonica Thumb.) extracted by water was developed using near-infrared (NIR) spectroscopy and the partial least-squares (PLS) method. The NIR spectra 81 samples collected from a production line were obtained. concentrations secologanic acid, chlorogenic acid galuteolin determined high-performance liquid chromatography-diode array detection as reference Several pretreatment methods used...
Supercritical fluid extraction (SFE) with high-speed countercurrent chromatography (HSCCC) was successfully used for the and isolation of ethyl p-methoxycinnamate (EPMC) cinnamate (EC) from Kaempferia galanga L. The SFE parameters including temperature, pressure entrainer volume were optimized by central composite design (CCD). Then crude extract separated HSCCC a two-phase solvent system composed n-hexane:ethyl acetate:methanol:water (7:3:8:2, v/v/v/v) in one-step within 60 min. As result,...
The kinetics of the extraction tea seed oil with supercritical CO2was studied. A kinetic model using CO2 was developed on basis differential mass balance to simulate process. could distribution solute concentration in inside bed as a function time and height bed. also at outlet extractor time. effects parameters such pressure temperature yield process were investigated through model. This satisfactorily an error between simulation data experimental less than 10%.
In this study, four sterols were isolated from the Ganoderma lucidum spores oil obtained via supercritical CO2 extraction. Four chemical constituents ganoderin A (1), chaxine B (2), ergosterol, (3) and stellasterol (4). All separated ingredients characterized using spectral data interpretation by comparing with reported data. Noticeably, both firstly was shown to bear an unprecedented skeleton.
Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection (SLGI) was made of miltiorrhiza Bge., glucose, glycerin. There were many kinds monosaccharide components in SLGI, which might be from the raw material Bge. Separation performed on a Phenomenex Luna C18 analytical column (250 mm × 4.6 i.d., 5 μm, AccuStandard Inc., USA) at 30°C. The mobile phase consisted two solvents: 0.1 mol/L phosphate-buffered saline (pH 6.7) (solvent A) acetonitrile B) with gradient elution. flow...