A5075134614- Analytical Methods in Pharmaceuticals
- Drug Solubulity and Delivery Systems
- 3D Printing in Biomedical Research
- Advanced Drug Delivery Systems
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Antibiotics Pharmacokinetics and Efficacy
- Advancements in Transdermal Drug Delivery
- Hepatitis C virus research
- Natural Antidiabetic Agents Studies
- Pharmaceutical studies and practices
- HIV/AIDS drug development and treatment
- Spaceflight effects on biology
- Digestive system and related health
- Pharmacogenetics and Drug Metabolism
- Biosimilars and Bioanalytical Methods
- Food composition and properties
- Polysaccharides Composition and Applications
- Lipoproteins and Cardiovascular Health
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 and COVID-19 Research
- Inhalation and Respiratory Drug Delivery
- Food and Agricultural Sciences
- Biochemical and Molecular Research
- Analytical Chemistry and Sensors
Kanya Maha Vidyalaya
2023
Nirma (India)
2013-2020
Acharya Nagarjuna University
2014-2019
Guntur Medical College
2013-2018
Indian Institute of Technology Kharagpur
2014-2015
Al Zawiya University
2013-2015
Creative Research Enterprises (United States)
2015
University of Malaya
2015
Netaji Subhas University of Technology
2015
In recent times solvent evaporation techniques have gained prominence in microencapsulation process. Solvent are broadly classified into emulsification solvent- and extraction methods. Several variations been developed recently based on this technology. Using methods we can regulate microsphere morphology other characteristics to the desired level for targeted delivery of bioactives like peptides vaccines using various biomaterials as carriers. evaporation, core coat materials used, emulsion...
A simple, sensitive and specific liquid chromatography–tandem mass spectrometry method was developed for simultaneous quantification of ezetimibe simvastatin in rat plasma. The deuterium isotopes: d4 d6 were used as internal standards simvastatin, respectively. MS/MS detection involved a switch electron spray ionization mode from negative to positive at retention time 3.01 min. Samples extracted plasma by liquid–liquid extraction using tertiary butyl methyl ether. Chromatographic separation...
A new simple, precise, accurate and selective RP - HPLC method has been developed validated for simultaneous es timation of cinnarizine (CIN ) d omperidone (DOM) in tablet dosage form. The was carried out on a C 18 (250mm × 4.6mm i.d, 5µm) column with mobile phase consisting m ethanol cetonitrile the ratio (70:30 v/v) flow rate 1.0 mL min 1 . detection at 270 nm. retention time CIN DOM were f ound to be 3.389 4.793 respectively. followed linearity concentration range o 40 160 μg 45 105 r 2 =...
Ciprofloxacin, commonly used in India as an anti-microbial for prolonged use chronic and non-specific indications, may affect the bioavailability of drug. The drug prescribed is taken with multivitamins, calcium milk. A simple reliable analytical methodology obtaining a correlation vivo urinary excretion studies using UV HPLC vitro dissolution (IVIVC) has shown significant increase elimination rate ciprofloxacin co-administered Appreciable IVIVC results proved that could serve alternative to...
Design of experiment (DOE) approach reinforces the robustness method being developed. This was employed for UV-visible (200-400 nm and 400-800 respectively) RP-HPLC development using C<SUB>18</SUB> inertsil column optimization variables ambrisentan (ABN) estimation in bulk formulations. A two-level full factorial design assisted a visible spectroscopic based on principle oxidation coupling reaction ABN with 3-methyl-2-benzothiazolinone hydrazone (MBTH reagent) presence FeCl<SUB>3</SUB> to...
Despite tremendous strides in modern medicine stringent control over insulin resistance or restoration of normoglycemia has not yet been achieved.With the growth molecular biology, omics technologies, docking studies, and silico pharmacology, modulators
The current research aims to formulate Venlafaxine Sustained Release (VHL-SR) tablets using hydrophilic-hydrophobic polymers combination blends by melt granulation technique which highlights the novelty. selected for present study have matrix forming properties. Results of FTIR studies shown that there were no interactions between used and drug VHL. Various formulations VHL- SR (F1-F16) different combinations hydrophilic hydrophobic viz. Carbopol 71G, HPMC K15M, PEO, sodium CMC, Eudragit...
The world has witnessed growing complexities in disease scenario influenced by the drastic changes host-pathogen- environment triadic relation. Pharmaceutical R&Ds are constant search of novel therapeutic entities to hasten transition drug molecules from lab bench patient bedside. Extensive animal studies and human pharmacokinetics still "gold standard" investigational new research bio-equivalency studies. Apart cost, time ethical issues on experimentation, burning questions arise relating...
Objectives: This review provides a detailed of the treatment obesity with natural products that are formulated as phytosomes. When novel drug delivery technology is used instead traditional in herbal medicine, side effects reduced while safety and efficacy improved.This article information about along its special emphasis on phytosomes, their preparation evaluation application obesity. Methods: A comprehensive search electronic databases such Medline, Embase, Cochrane Library, Google, Google...
The severe acute respiratory syndrome coronavirus 2, well known as COVID-19 has become the current health distress to entire world. In pandemic scenario research on rapid development of new drug molecules is highly risky and tedious process. emergency demands an urgent possible strategies protect people at high risk infection hence repurposing became emerging approach fight COVID-19. This review summarizes update various therapeutic with special attention drugs against SARS-CoV-2 worldwide....
Present study aims at comparative evaluation of drug release and permeability diclofenac sodium loaded ethylcellulose (EC), cellulose acetate (CA) eudragit (EU) microspheres. Microspheres EC, CA EU containing were prepared by an emulsification-solvent evaporation (oil-in-oil, o/o) method investigated for a various parameters. The microspheres found discrete, free flowing, multinucleate, monolithic spherical. About 5560% all in the size range -20+30 (715 m) mesh size. encapsulation...
Abstract The aim of the present study was to synthesize potato starch (PS) derivatives tartaric acid (TA) under semi‐dry conditions and evaluate physicochemical properties as per official compendia requirements. Starch tartrate (ST) synthesized by reacting PS (St–OH) TA in condition using sodium hypophosphite (SHP) a catalyst. Further we have applied its use disintegrant directly compressed telmisartan tablets. microscopic, spectroscopic (FTIR), thermal (DSC) crystallographic (XRD) studies...
Abstract Background The study aims to develop a chemometrics optimized D-optimal mixture design approach assisted RP- HPLC method for the determination of pesticide residues metsulfuron-methyl, chlorantraniliprole, and chlorimuron-ethyl in stems Oryza sativa . Chromatographic separation was achieved on C18 column using mobile phase consisting pH 3.5 phosphate buffer acetonitrile ratio 85:15. Results gave sharp resolution chlorantraniliprole at retention time 2.599 min, 3.805 min 4.661...