A5073146833- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Nutritional Studies and Diet
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Screening and Detection
- Health disparities and outcomes
- Breastfeeding Practices and Influences
- Medical Imaging and Pathology Studies
- Estrogen and related hormone effects
- Systemic Lupus Erythematosus Research
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Dementia and Cognitive Impairment Research
- Breast Cancer Treatment Studies
- Sensory Analysis and Statistical Methods
- Breast Lesions and Carcinomas
- Metabolism, Diabetes, and Cancer
- Endometrial and Cervical Cancer Treatments
- Eating Disorders and Behaviors
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Infant Nutrition and Health
Tohoku University
2013-2024
Ibarakihigashi National Hospital
2016-2024
National Hospital Organization
2016-2024
International Association for the Study of Lung Cancer
2024
Osaki Citizen Hospital
2018-2023
Miyagi Prefectural Hospital Organization
2006-2022
Tochigi Cancer Center
1995-2019
Chuo University
2018-2019
Nichia Corporation (Japan)
2017-2019
University of Tsukuba Hospital
2000-2016
During recent decades, breast cancer incidence has been increasing in Japan. According to the latest reports from several registries Japan, become leading site female incidence. To analyze trend of detail, we summarized Miyagi Prefecture, Japan during 1959-1997, and evaluated period cohort effect on using age-period-cohort model. Age-specific age-standardized rates have increased over successive calendar periods. Around 1980, an accelerated increase these took place. A full model including...
Objective: To examine the predictive power of self‐rated health, activities daily living (ADL), and ambulatory activity for different causes death in a representative sample older persons. Design: Three‐year prospective cohort study. Setting: Sendai City, Japan. Participants: 2,552 persons 65 years at baseline 1988. Measurements: Independent variables (measured by self‐report participants) were age, sex, ADL, level, use medical care. Dependent mortalities from cancer, stroke, heart disease....
The role of adult weight change in breast cancer (BC) risk is unclear Japanese women. A total 10 106 postmenopausal women aged 40–64 years (the Miyagi Cohort) were followed from 1990 to 2003, and 108 BC cases identified. Hazard ratios (HRs) estimated according body mass index (BMI) at the current age 20 years, since years. Higher BMI was associated with an increased (P for trend=0.02), whereas higher inversely this trend=0.002). There a significant association between trend=0.0086). Compared...
Since the eight edition of Union for International Cancer Control and American Joint Committee on TNM classification system, primary tumor pT stage is determined basis presence size invasive components. The aim this study was to identify histologic features in tumors with lepidic growth pattern which may be used establish criteria distinguishing from noninvasive areas.A Delphi approach two rounds blinded anonymized analysis resected nonmucinous lung adenocarcinoma cases presumed components,...
Body mass index (BMI) may be an important factor affecting breast cancer outcome. Studies conducted mainly in Western countries have reported a relationship between higher BMI and risk of all-cause death or cancer-specific among women with cancer, but only few studies been Japan so far. In the present prospective study, we investigated associations patients overall by menopausal status hormone receptor status. The study included 653 admitted to single hospital Japan, 1997 2005. was assessed...
To assess the relation of lifestyle factors, personality and some biologic markers to cancer incidence, evaluate effectiveness screening, a cohort study was conducted among all residents aged 40 64 years in 14 municipalities Miyagi Prefecture, Japan. The baseline survey consisted self-completed questionnaires concerning (Eysenck Personality Questionnaire-Revised), serum samples collected from part subjects. proportion subjects who appropriately responded questionnaire (response rate) 91.7%...
Although cigarette smoking is a well‐known risk factor of lung cancer, associations with the other sites have not been fully elucidated in Japan. To simultaneously evaluate risks cancers stomach, lung, colon, and rectum, which leading cancer recent years Miyagi Prefecture, Japan, we conducted hospital‐based case‐control study. Study subjects consisted 614 515 324 164 rectal cases 2444 hospital controls admitted to single Prefecture from 1997 2001. Information on habit lifestyle factors was...
During recent decades, colorectal cancer incidence rates have been rapidly increasing in Japan. To investigate trends rates, we analyzed data during 39 years between 1959 and 1997 Miyagi Prefecture, Japan.Using age-period-cohort models, evaluated the effects of time period cohort on colon rectal incidence. Model fitting was based eleven 5-year age groups (30-34 to 80-84), eight periods, 18 overlapping birth cohorts 10 each.The analysis found a significant (p=0.04) upward effect female...
During recent decades, the incidence of gynecologic cancers, i.e., cancers cervix, endometrium and ovary, has increased in Japan. However, risk factors have not been fully clarified To investigate common site-specific among we conducted a hospital-based case-control study. The cases, 151 cervical, 103 endometrial 141 ovarian cancer cases controls (n = 2016) were selected from female patients aged 30 over, who admitted to single hospital Miyagi Prefecture 1997 2003. Information on...
Dietary factors may affect the prognosis of digestive tract cancer, but evidence has been sparse. We investigated association between pretreatment intake 6 Japanese foods (including soy food, miso [soybean paste] soup and seaweed) risk death among patients with histologically confirmed major cancers (stomach, 1931; colon, 793; rectum, 510) diagnosed during 1997-2013 at a single institution in Japan. Pretreatment dietary was assessed using food frequency questionnaire, were followed until...
Although cigarette smoking is a well‐known risk factor for lung cancer, histology‐specific has not been fully clarified in Japan. This case‐control study evaluated the associations between and cancer according to sex histologic type. From among patients aged 30 years over admitted single hospital Japan 1997 2009, 1670 cases 5855 controls were selected. History of smoking, quantity duration passive from spouses assessed using self‐administered questionnaire. Odds ratios (ORs) 95% confidence...
Background: Intakes of selected vitamins and dietary fiber may influence the clinical course systemic lupus erythematosus (SLE). Using a cohort study method, we investigated associations intake vitamin B6 B12, folate, with risk active disease atherosclerotic vascular events in SLE.Methods: The included female SLE patients Miyagi Lupus Cohort, which was founded 1995. Dietary nutrients at baseline were estimated by semiquantitative food frequency questionnaire. association each nutrient 216...
Family history and nutritional status may affect the long-term prognosis of stomach cancer, but evidence is insufficient inconsistent. To clarify prognostic factors we conducted a prospective study 1,033 Japanese patients with histologically confirmed cancer who were admitted to single hospital between 1997 2005. pretreatment body mass index (BMI) assessed using self-administered questionnaire. Clinical data retrieved from hospital-based registry. All completely followed up until December,...
Abstract An association of cigarette smoking with breast cancer risk has been hypothesized. However, results from previous studies have inconsistent. This case-control study investigated the in terms estrogen-receptor/progesterone-receptor (ER/PgR) status. From among female patients aged 30 years and over admitted to a single hospital Japan between 1997 2011, 1,263 cases (672 ER+/PgR+, 158 ER+/PgR-, 22 ER-/PgR+, 308 ER-/PgR- 103 missing) 3,160 controls were selected. History (ever, never),...
Cigarette smoking and alcohol drinking may affect the prognosis of stomach cancer, but evidence has been inconsistent. We investigated associations between pretreatment risk all‐cause cancer death among 1,576 patients with histologically confirmed diagnosed during 1997–2010 at a single hospital in Japan. Histories were assessed using self‐administered questionnaire. The followed until December 31, 2013. Cox proportional hazards model was used to estimate hazard ratios (HRs) 95% confidence...
Background The interactive effect of personal factors and social upon suicide risk is unclear. We conducted prospective cohort study to investigate whether the impact economic crisis in 1997–1998 differed according Neuroticism Psychoticism personality traits. Methods Miyagi Cohort Study Japan with a follow-up for 19 years from 1990 2008 has 29 432 subjects aged 40–64 at baseline who completed questionnaire about various health habits Japanese version Eysenck Personality Questionnaire –...
The associations between menstrual and reproductive factors breast cancer risk in relation to estrogen/progesterone receptor ( ER / P g R ) status have been unclear J apanese women. This case‐control study evaluated these associations, overall separately, by menopausal status. A total of 1092 cases 3160 controls were selected from among female patients aged 30 years over admitted a single hospital M iyagi refecture 1997 2009. distribution the (missing: 8.4%) was 571 +/ +, 133 −, 24 −/ + 271...
Previous studies indicated that serum β-carotene levels were low among smokers and drinkers. However these findings may result from the strong relationship between smoking drinking. Data collected 1902 males randomly selected participants of a cohort study. The effects on assessed according to drinking status (non-drinker, ex-drinker current drinker), those (non-smoker, ex-smoker smoker) using general linear model including other factors (age, intake green-yellow vegetables, carrot or...