A5006058334- Prenatal Screening and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Congenital Diaphragmatic Hernia Studies
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Cerebrospinal fluid and hydrocephalus
- Parvovirus B19 Infection Studies
- Maternal and Neonatal Healthcare
- Genetic and Kidney Cyst Diseases
- Renal and related cancers
- Neonatal Health and Biochemistry
- Cleft Lip and Palate Research
- Congenital Heart Disease Studies
- Tumors and Oncological Cases
- Ureteral procedures and complications
- Teratomas and Epidermoid Cysts
- Thyroid Disorders and Treatments
- Maternal and fetal healthcare
- Renal and Vascular Pathologies
- Thyroid Cancer Diagnosis and Treatment
- Genetic Syndromes and Imprinting
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2005-2024
Universidade de São Paulo
2000-2023
Aarhus University Hospital
2017
Sheffield Teaching Hospitals NHS Foundation Trust
2017
Universitair Ziekenhuis Brussel
2017
Vrije Universiteit Brussel
2017
Albany Molecular Research (United Kingdom)
2017
Tel Aviv University
2017
Hospital Universitário da Universidade de São Paulo
2005-2006
Hospital São Paulo
2005-2006
This study presents 18 cases of prenatally diagnosed congenital cystic adenomatoid malformation (CCAM) to identify potential factors that could predict prognosis. Comparisons prenatal parameters were made between fetuses survived and those died perinatally. It was found microcystic lesion, bilateral lung involvement hydrops each highly correlated with poor prognosis, while neither polyhydramnios nor mediastinal shift significantly associated had outcome. Fetal interventions indicated only in...
Fetuses with trisomy 21 typically present subtle facial abnormalities, including a hypoplastic nasal bone. The aim of this study was to provide reference range for the length fetal bone and test its value in second-trimester ultrasound screening 21.A established from cross-sectional data on 1923 consecutive singleton pregnancies scanned at 16-24 weeks' gestation women older than 35 years. Screening prospectively studied using measurement lengths smaller 5(th) percentile as cut-off...
Abstract Objective To report the experience with fetal cystoscopy and laser fulguration of posterior urethral values (PUV) for severe lower urinary tract obstruction (LUTO). Methods Between July 2006 December 2008, was offered to 23 patients whose fetuses presented LUTO, favorable analysis gestational age <26 weeks. Fetal biochemistry evaluated before after cystoscopy. All infants were followed 6–12 months birth. Abnormal renal function defined when serum creatinine higher than 50 µmol/L...
The purpose of this study was to estimate the Down syndrome detection and false-positive rates for second-trimester sonographic prenasal thickness (PT) measurement alone in combination with other markers.Multivariate log Gaussian modeling performed using numerical integration. Parameters PT distribution, multiples normal gestation-specific median (MoM), were derived from 105 1385 unaffected pregnancies scanned at 14 27 weeks. data included a new series 25 cases 535 controls combined 4...
To evaluate the perinatal results for neonates with congenital diaphragmatic hernia diagnosed prenatally.We reviewed data from 38 cases of prenatally January 1995 to December 2003 in Fetal Medicine Unit Department Obstetrics and Gynecology, São Paulo University Medical School. The main analyzed were gestational age at diagnosis, fetal karyotyping, side defect, presence associated structural malformations, hepatic herniation, severe mediastinal shift. Perinatal outcomes obtained by reviewing...
Final assessment on the outcome of fetal obstructive uropathy is a challenging matter. Ultrasonography, urine electrolytes, and beta 2 microglobulin are postulated as being useful in many cases. For cases which renal function remains unclear, ultrasound-guided kidney biopsy may be used order to detect histologic features distinctive dysplasia. We present preliminary results aimed at studying feasibility possible risks. Biopsies were initially performed 11 severely malformed fetuses, three...
<i>Background/Aims:</i> To present a protocol of immediate surgical repair myelomeningocele (MMC) after birth (‘time zero’) and compare this outcome with the surgery performed newborn’s admission to nursery before operation. <i>Methods:</i> Data from medical files 31 patients MMC that underwent at (group I) were compared group 23 admitted prospectively followed, who immediately – ‘at time zero’ II). <i>Results:</i> The preoperative rupture occurred more...
Objective. The purpose of this study was to assess the agreement between 3-dimensional ultrasonography (3DUS) and magnetic resonance imaging (MRI) for lung volumetry in fetuses with without abnormalities associated hypoplasia. Methods. Fifty-nine singleton pregnancies were evaluated. Cases separated into groups 1 2, according presence or absence malformations hypoplasia, respectively. Fetal volume calculated by Virtual Organ Computer-Aided Analysis (VOCAL) program 3DUS MRI. In both groups,...
The object of this study was to explore the role folate in pathophysiology neural tube defects (NTD). Maternal and fetal serum red blood cell were assayed 14 cases NTDs compared with controls other malformations matched for gestational age (range 18–36 weeks). In mothers NTD fetuses, (5.2 ng/ml), (294 ng/ml) methylation rate (65%) significantly lower than (6.6 399 ng/ml, respectively, 77%). However, status similar controls. group, metabolism altered but not fetuses. Therefore, a normal...
This study presents 30 cases of fetal isolated spina bifida aperta (SBA) to identify prenatal ultrasound findings that could predict the prognosis. Comparisons between surviving patients who had normal (group 1) and abnormal 2) post-natal neurological outcomes were made for three different signs, is, site vertebral lesion, presence degree ventriculomegaly talipes. The lesion was most significant outcome predictor, as high spinal dysraphisms observed in 2 (2/7-28.6%) group 1 15 (15/19-79.0%)...
Myelomeningocele (MMC) is a neural tube defect disease. Antenatal repair of fetal MMC an alternative to postnatal repair. Many agents can be used as tocolytics during the in utero such β2-agonists and oxytocin receptor antagonists, with possible maternal repercussions. This study aims compare arterial blood gas analysis between terbutaline or atosiban, tocolytic agents, intrauterine
A fenda facial sempre intrigou a sociedade por ser uma malformação que estigmatiza seus portadores. Os poucos dados relacionados à observação ultrassonográfica pré-natal dessa malformação, no Brasil, incentivaram o seu estudo Setor de Medicina Fetal do departamento ginecologia e obstetrícia hospital das clínicas da faculdade medicina universidade São Paulo (DOG, HCFMUSP). Métodos objetivos: O foi desenvolvido maneira descritiva, sendo selecionados 97 fetos portadores diagnosticada ao...
Objectives To evaluate whether fetal urinary sodium and chloride provide clinically useful information in addition to ultrasound bilateral obstructive uropathy. Methods Sonographic features concentrations of were evaluated fetuses with After a minimum 12 months postnatal follow-up, cases that developed increased serum creatinine (greater than 50 µmol/L) compared those did not. Results Of the studied, 16/35 died perinatally, all showing anamnios markedly elevated electrolytes. survivors, ten...
<b>Purpose</b> To evaluate the precision of both two- and three-dimensional ultrasonography in determining vertebral lesion level (the first open vertebra) patients with spina bifida. <b>Methods</b> This was a prospective longitudinal study comprising fetuses bifida who were treated fetal medicine division department obstetrics Hospital das Clínicas Universidade de São Paulo between 2004 2013. Vertebral established by using 50 (two examiners each method). The neonatal period radiological...
Abstract A case of Meckel—Gruber syndrome was diagnosed by embryoscopy at 10 menstrual weeks, allowing for early termination pregnancy. Post‐mortem examination confirmed the presence polydactyly and bilateral cystic lesions mesonephros metanephros. Both forming nephrons collecting ducts were involved in formation renal cysts.
Abstract We report a case of congenital splenic cyst that was identified by prenatal sonography at 25 gestational weeks. Serial scans demonstrated an increase in size during the period but after birth progressively decreased until its complete regression 6 months age. Copyright © 2001 International Society Ultrasound Obstetrics and Gynecology
Abstract Neuroblastoma is the most frequent extracranial solid tumor in childhood, but it seldom diagnosed prenatally. We report a case of adrenal neuroblastoma identified at 39 weeks' menstrual age and successfully treated by postnatal surgery chemotherapy. Sonography revealed hyperechoic mass right upper quadrant fetal abdomen associated with hydramnios hydronephrosis. Two days after delivery, was resected. No metastasis identified. The infant received 6 cycles chemotherapy, 2 years she...
Objetivos: avaliar casos de fenda facial fetal quanto ao tipo lesão, associação com outras malformações e aneuploidias. Métodos: as fendas faciais foram estudadas a idade materna antecedentes, gestacional no diagnóstico, lado da presença associadas e/ou aneuploidias, mortalidade seguimento pós-natal. Resultados: em 40 fetos fenda, lesão era labial pura 18 (45%), labiopalatina 19 (47,5%) palatina 3 (7,5%). Em 10 isolada (25%), todas unilaterais. No grupo associadas, aneuploidia esteve...
We report two cases of exencephaly diagnosed by transvaginal ultrasonography at 8 weeks 4 days and 9 3 gestation. Both presented an irregular cephalic pole, and, in the case seen days, brain vesicles were also absent, whereas midline echo was indistinguishable with disorganized choroid plexuses. In both cases, anencephaly evident 11 12 weeks' gestation postmortem confirmed diagnosis. Copyright © 2005 John Wiley & Sons, Ltd.