A5000500230- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Neurosurgical Procedures and Complications
- Blood Pressure and Hypertension Studies
- Sodium Intake and Health
- Intracerebral and Subarachnoid Hemorrhage Research
- Nutritional Studies and Diet
- Wildlife-Road Interactions and Conservation
- Head and Neck Surgical Oncology
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular Health and Disease Prevention
- Image Processing and 3D Reconstruction
- Cardiac Arrest and Resuscitation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cleft Lip and Palate Research
- Glioma Diagnosis and Treatment
- Nerve Injury and Rehabilitation
- Vascular Malformations Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Peripheral Nerve Disorders
- Neurological and metabolic disorders
- Moyamoya disease diagnosis and treatment
- Genetic and Kidney Cyst Diseases
Royal Hospital for Children
2024-2025
Universidade de São Paulo
2011-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2013-2024
Hospital de Santo António
2024
Universidade Federal do Maranhão
2023
Hospital San Borja Arriarán
2023
Beneficência Portuguesa de São Paulo
2022
Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2011-2021
Hospital Universitário da Universidade de São Paulo
2007-2020
Hospital do Servidor Público Estadual
2009-2019
Objective: To determine prevalence, awareness, treatment and control of hypertension the 24-h sodium excretion (24h-UNa) in Portuguese adult population to examine their changes from a similar study done 2003. Design setting: A population-based cross-sectional survey conducted 2011–2012. Methods: multistage-stratified (by age sex) sampling method was used select representative sample 18–90-year-old yielding 3720 participants (52.6% women, 97.1% Caucasians). Hypertension defined as SBP at...
Currently, the most common treatment for idiopathic normal pressure hydrocephalus (INPH) is a ventriculoperitoneal shunt (VPS), generally with programmable valve implantation. Endoscopic third ventriculostomy (ETV) another option, and it does not require prosthesis implantation.To compare functional neurological outcome in patients after 12 months of INPH by using 2 different techniques: ETV or VPS.Randomized, parallel, open-label trial involving study 42 positive response to tap test, from...
Background and objectives: The SBP values to be achieved by antihypertensive therapy in order maximize reduction of cardiovascular outcomes are unknown; neither is it clear whether patients with a previous event, the optimal lower than low-to-moderate risk hypertensive patients, or more cautious blood pressure (BP) should obtained. Because uncertainty ‘the better’ ‘J-curve’ hypothesis correct, European Society Hypertension Chinese League have promoted randomized trial comparing treatment...
The aim of this study was to assess the validity estimation 24-h urinary sodium (UNa) and potassium (UK) excretion obtained through four formulae based on occasional urine samples.We analysed 2399 individuals (51% females) aged 18 96 years representatives Portuguese population. Tanaka, Kawasaki, INTERSALT NHANES were used predict UNa UK excretions from spot morning samples (OUrS). We compared it with validated real (VUrS) (24-h UNa: 4052 ± 1432 mg/day, = 2928 1004 mg/day). observed vs....
Background Studies on the implantation of care routines showed reduction EVD catheter-related infections rates; however zero tolerance is difficult to be achieved. The objective this study was assess impact an educational intervention maximal rates EVD-related infections. Methodology/Principal Findings quasi-experimental (before-after intervention) occurred in two phases: pre-intervention, from April 2007 July 2008, and intervention, August 2008 2010. Patients were followed for 30 days after...
Normal pressure hydrocephalus (NPH) is characterized by gait disturbance, dementia and/or urinary incontinence associated with dilation of ventricular system normal opening cerebrospinal fluid pressure. Wide scientifical evidence confirms association between NPH and psychiatric symptoms. We selected 35 patients idiopathic from January 2010 to 2012 in a Brazilian tertiary hospital performed formal evaluation identify disorders. Psychiatric disorders were present 71% these patients, especially...
The filum terminale (FT) is a fibrovascular band involved in the pathophysiology of tethered cord syndrome (TCS). Its morphological and ultrastructural properties remain largely unknown even though they are thought to play role generation TCS adult patients with normal level conus medullaris.Twenty fresh human cadavers had their fila measured removed. Transversal longitudinal sections proximal, middle, distal thirds FT were submitted light microscopy analysis four different techniques. Five...
Cerebral hemiatrophy or Dyke-Davidoff-Masson syndrome is a condition characterized by seizures, facial asymmetry, contralateral hemiplegia hemiparesis, and mental retardation. These findings are due to cerebral injury that may occur early in life utero. The radiological features unilateral loss of volume associated compensatory bone alterations the calvarium, like thickening, hyperpneumatization paranasal sinuses mastoid cells elevation petrous ridge. authors describe three cases. Classical...
The devastating effects of hypotension on head-trauma-related mortality are well known. This study evaluates the systemic and cerebral hemodynamic responses to volume replacement with 3% hypertonic saline (HSS) or lactated Ringer's solution (LR), during acute phase hemorrhagic shock (HS) associated traumatic brain injury (TBI).Fifteen dogs were assigned one three groups (n = 5, each) according protocol, infused after TBI (brain fluid percussion, 4 atm) epidural balloon an intracranial...
Idiopathic normal pressure hydrocephalus (iNPH) is characterized by gait disturbance, dementia and /or urinary incontinence, dilation of the ventricular system opening cerebrospinal fluid pressure. Shunt surgery standard treatment iNHP. Diversions with programmable valves are recommended, once drainage can be changed. However, well-defined protocols still lack guiding steps to attain proper for each patient. Methods: In our study, we reported experience shunting 24 patients iNPH using...
Departamento de Hipertensao Arterial da Sociedade Brasileira Cardiologia, Rio Janeiro, RJ - Brazil
Chronic meningitis caused by Sporothrix sp. is occasionally described in immunosuppressed patients. We report the challenges diagnosing and managing 2 nonimmunocompromised patients with hydrocephalus chronic brasiliensis. This more virulent species appears to contribute atypical severe cases than other related species.
To evaluate the intradural anatomic features of filum terminale (FT) in fresh human cadavers, analyzing morphological parameters relevant for diagnosis tethered cord syndrome.Forty-one cadavers were dissected, and following evaluated: cadaver height, weight, age, FT length, diameters at initial point midpoint, topographic relationships fusion points to adjacent vertebrae.The mean length was 156.44 mm (range, 112.8-211.1 mm), diameter 1.38 0.4-2.5 midpoint 0.76 0.1-1.55 mm). Four specimens...
Guyon's canal syndrome, an ulnar nerve entrapment at the wrist, is a well-recognized entity. The most common causes that involve wrist are compression from ganglion, occupational traumatic neuritis, musculotendinous arch and disease of artery. We describe two cases syndrome discuss anatomy, aetiology, clinical features, anatomical classification, diagnostic criteria treatment. It emphasized knowledge both surgical technique anatomy very important for satisfactory result.