Xinxin Li

ORCID: 0000-0003-3197-576X
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About
Contact & Profiles
Research Areas
  • Ophthalmology and Visual Impairment Studies
  • Retinal Imaging and Analysis
  • Retinal Diseases and Treatments
  • Intraocular Surgery and Lenses
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Blood Pressure and Hypertension Studies
  • Muscle activation and electromyography studies
  • Adsorption and biosorption for pollutant removal
  • Antifungal resistance and susceptibility
  • Intracranial Aneurysms: Treatment and Complications
  • Meningioma and schwannoma management
  • Vascular Malformations Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Minerals Flotation and Separation Techniques
  • Cardiovascular Health and Disease Prevention
  • Muscle metabolism and nutrition
  • Plasma Applications and Diagnostics
  • Ocular Surface and Contact Lens
  • Management of metastatic bone disease
  • Coronary Interventions and Diagnostics
  • Coronary Artery Anomalies
  • Ocular Infections and Treatments
  • Ocular and Laser Science Research

Beijing Sport University
2025

Central South University
2011-2024

National Institute of Measurement and Testing Technology
2023

First Affiliated Hospital of Zhengzhou University
2023

Chinese University of Hong Kong
2023

Creative Commons
2022

He Eye Hospital
2022

First Hospital of China Medical University
2022

China Medical University
2022

Centre de Recherche des Cordeliers
2019

Abstract Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections. Here we report that treatment with the oral mineralocorticoid receptor (MR) antagonist spironolactone reduces signs CNV treatment. In animal models AMD, pharmacological inhibition MR pathway or endothelial-specific deletion inhibits through VEGF-independent mechanisms, part...

10.1038/s41467-018-08125-6 article EN cc-by Nature Communications 2019-01-21

To evaluate the effectiveness of intraoperative neuromonitoring (IONM) during arteriovenous malformation (AVM) surgery, we retrospectively analyzed neurologic dysfunction in patients who underwent AVM surgery with (IONM group) and without IONM (non-IONM group). The sensitivity specificity short-term were calculated group. parameters obtained all patients. There was no significant difference between non-IONM groups. hemiplegia ratio among grade III group significantly lower than for...

10.1097/md.0000000000008054 article EN cc-by-nc Medicine 2017-09-01

This study evaluates if there is an association between lifestyle changes and the risk of small vessel disease (SVD) as measured by cerebral white matter hyperintensities (WMH) estimated automatic retinal image analysis (ARIA) method. We recruited 274 individuals into a community cohort study. Subjects were assessed at baseline annually with Health-Promoting Lifestyle Profile II Questionnaire (HPLP-II) underwent simple physical assessment. Retinal images taken using non-mydriatic digital...

10.3390/ijerph20043530 article EN International Journal of Environmental Research and Public Health 2023-02-16

Introduction: This is a report of cataract surgery in post–small-incision lenticule extraction (SMILE) patient with low myopia. Patient and clinical findings: A 49-year-old man underwent bilateral SMILE 18 months previously, the visual acuity both eyes recovered to 20/20. The noticed gradual reduction his left eye blurring for 3 months. corrected distance (CDVA) was 20/67 eye. Diagnosis, intervention, outcomes: slitlamp examination revealed an anterior subcapsular cataract. intraocular lens...

10.1097/j.jcro.0000000000000071 article EN Journal of Cataract and Refractive Surgery Online Case Reports 2022-02-23

Fluctuating anterior chamber depth and reverse pupillary block are the most common problems encountered during phacoemulsification following pars plana vitrectomy in cases of cataracts. The sudden deepening makes surgical procedure more cumbersome increases risk intraoperative complications. To solve this problem, we describe a method balancing pressure posterior by using syringe with flushing needle to inject balanced salt solution into via gap between iris capsule lens. This technique is...

10.1177/1120672120940192 article EN European Journal of Ophthalmology 2020-07-03

To the Editor: The prevalence of high myopia (HM) has been increasing globally, particularly in young Chinese population.[1] Most early investigations on ocular biometric parameters myopic individuals focused primarily children, adolescents, and elderly with cataracts, leaving a dearth research among adults HM. Additionally, associations between axial length (AL) HM are unclear.[2,3] Therefore, understanding characteristics their correlations AL is crucial. Ocular serve as fundamental basis...

10.1097/cm9.0000000000003323 article EN cc-by-nc-nd Chinese Medical Journal 2024-11-06

To evaluate the therapeutic effect of incorporating continuous administration voriconazole in treatment recalcitrant fungal keratitis.In this prospective case study, 5 consecutive patients (5 eyes) with keratitis were treated a standard protocol after failing maximal conventional medical treatment. The involved lavage ulcer 1% through an irrigator for 2 h, twice day, combined local and systemic antifungals. Visual acuity, slit lamp findings ulcer, hyphae density by confocal microscope...

10.1177/11206721211068628 article EN European Journal of Ophthalmology 2021-12-17

Abstract Purpose To explore the accuracy of improved SRK/T-Li formula in eyes following implantation intraocular lens (IOL) less than 10 D as calculated by using SRK/T Chinese. Methods A total 489 from patients with cataracts were included this study. These divided into a training set (271 patients) and testing (218 patients). The IOL power was D. We evaluated modified (P = P × 0.8 + 2 implanted power; SRK/T)). mean absolute error (MAE), percentage prediction (PE) within ± 0.25, 0.50, 1.00...

10.21203/rs.3.rs-2854552/v1 preprint EN cc-by Research Square (Research Square) 2023-04-27

Outside Front Cover: Microwave atmospheric pressure plasma jet generated from substrate integrated waveguide resonator by Chaoxia Zhao et al (e2200230).

10.1002/ppap.202370011 article EN Plasma Processes and Polymers 2023-06-01

Objective: To investigate the effects of application a low addition refractive multifocal intraocular lens (IOL) using micromonovision design in non-dominant eye with different degrees preset myopia on visual acuity, function and quality after bilateral cataract surgery. Methods: In this randomized controlled trial, patients who were proposed to undergo phacoemulsification combined rotational asymmetric IOL (MF15 IOL) implantation at First Affiliated Hospital Zhengzhou University between...

10.3760/cma.j.cn112142-20230220-00060 article EN PubMed 2023-12-11

Objective To investigate the clinical significance of 18F-FDG PET/CT in assessment Tomita score spinal metastases. Methods From October 2012 to 2015, a total 77 patients (38 males, 39 females; average age: 56.5 years) with suspicious metastasis tumors underwent scan and were included this retrospective study. Spinal confirmed by pathology. Each patient was evaluated scoring system according grade malignancy primary lesions organs bones PET/CT. Results Seventy-two osteolytic...

10.3760/cma.j.issn.2095-2848.2017.01.008 article EN Zhonghua heyixue yu fenzi yingxiang zazhi 2017-01-25

Optical coherence tomography angiography (OCTA) is a new imaging technology that allows the non-invasive and rapid reconstruction of three-dimensional structure retinal choroidal vascularization. Importantly, blood flow signals within vessels can be derived from consecutive scans selected areas. OCTA show vascular consistent with conventional angiography, although it cannot yet calculate filling time evaluate function blood-retinal barrier. reveal deep capillary networks better than ever...

10.3760/cma.j.issn.1674-845x.2017.10.001 article EN Chinese Journal of Optometry & Ophthalmology 2017-10-25

Abstract AIM To estimate the efficacy of oral spironolactone in patients with chronic central serous chorioretinopathy (CSC). METHODS This was a pilot study consisting who were diagnosed for at least 6-month duration. included 75 eyes 74 treated (20 mg orally, twice daily) 8 weeks. The best corrected visual acuity (BCVA), subretinal fluid (SRF), macular thickness (CMT) and subfoveal choroidal (SFCT) each measured baseline, 4 weeks RESULTS In our study, (49 men 25 women) included. mean BCVA...

10.21203/rs.2.11867/v1 preprint EN cc-by Research Square (Research Square) 2019-07-25
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