- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- Synthesis and biological activity
- Cancer Cells and Metastasis
- Extracellular vesicles in disease
- Free Radicals and Antioxidants
- Eicosanoids and Hypertension Pharmacology
- Gut microbiota and health
- Cancer, Lipids, and Metabolism
- Immune Cell Function and Interaction
- Angiogenesis and VEGF in Cancer
- Natural product bioactivities and synthesis
- Cancer, Hypoxia, and Metabolism
- Ginseng Biological Effects and Applications
- Genomics, phytochemicals, and oxidative stress
Nanjing University of Chinese Medicine
2021-2024
Aberrant tumor blood vessels are prone to propel the malignant progression of tumors, and targeting abnormal metabolism endothelial cells emerges as a promising option achieve vascular normalization antagonize progression. Herein, we demonstrated that salvianic acid A (SAA) played pivotal role in contributing tumor-bearing mice, thereby improving delivery effectiveness chemotherapeutic agent. SAA was capable inhibiting glycolysis strengthening junctions human umbilical vein (HUVECs) exposed...
At present, tumor metastasis still remains the leading contributor to high recurrence and mortality in cancer patients.There have been no clinically effective therapeutic strategies for treating patients with metastatic cancer.In recent years, a growing body of evidence has shown that pre-metastatic niche (PMN) plays crucial role driving metastasis.Nevertheless, clear detailed understanding formation PMN is lacking given fact involves wealth complicated communications underlying mechanisms...
Objective: The objective of this study was to investigate the mechanism by which total ginseng extract (TGE) inhibits progression lung cancer through network pharmacology and experimentation. Materials Methods: A Lewis carcinomas (LLC) model established injecting cells tail vein administering different doses TGE. infiltrated immune into microenvironment metastasis flow cytometry were evaluated, messenger RNA (mRNA) expression levels various cell-related chemokines determined using...